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null Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate. Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kinase kinase kinase (MAPKKK), resulting in activation of MAPKKK. MAPKKK signaling pathways relay, amplify and integrate signals from the plasma membrane to the nucleus in response to a diverse range of extracellular stimuli. null Catalysis of the phosphorylation and activation of JUN kinase kinase kinases (JNKKKs).

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: MAP kinase kinase kinase kinase activity
Acc: GO:0008349
Aspect: Molecular Function
Desc: Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kinase kinase kinase (MAPKKK), resulting in activation of MAPKKK. MAPKKK signaling pathways relay, amplify and integrate signals from the plasma membrane to the nucleus in response to a diverse range of extracellular stimuli.
Synonyms:
  • MAPKKKK
Proteins in PDR annotated with:
   This term: 5 [Search]
   Term or descendants: 5 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008349 - MAP kinase kinase kinase kinase activity (interactive image map)
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