| Protein: | sgk-1 |
| Organism: | Caenorhabditis elegans |
| Length: | 453 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
|
Region A: Residues: [1-396] |
1 11 21 31 41 51
| | | | | |
1 MVRKDEVTCN VIIGDDKKTV VYALRIGNGP IMQKTFEEYE RFFTTEKDMI PATIFTAPKK 60
61 KFLQADSKFY EKRRVWILVI SQHLVDNNLR SEDVRRFFHL ESPDDDENNV DLGPSERKTA 120
121 TANDFDYLTT IGKGSFGRVY QVRHKETKKI YAMKILSKEH IRKKNEVKHV MAERNVLINN 180
181 FKHPFLVSLH FSFQNKEKLY FVLDHLNGGE LFSHLQREKH FSESRSRFYA AEIACALGYL 240
241 HEKNIIYRDL KPENLLLDDK GYLVLTDFGL CKEDMQGSKT TSTFCGTPEY LAPEIILKKP 300
301 YDKTVDWWCL GSVLYEMIFG LPPFYSKDHN EMYDKIINQP LRLKHNISVP CSELITGLLQ 360
361 KDRSKRLGHR NDFRDIRDHP FFLPVDWDKL LNRELK
|
| Detection Method: |  |
| Confidence: | 54.0 |
| Match: | 2ptkA |
| Description: | CHICKEN SRC TYROSINE KINASE |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| cyclic nucleotide-dependent protein kinase activity | 4.97855712164511 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| cAMP-dependent protein kinase activity | 4.66277812893755 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| calmodulin-dependent protein kinase activity | 4.31938467136214 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 2.8153155526437 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.59526003830791 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 2.54265774272269 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 2.52531786618214 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 2.46424348876434 | bayes_pls_golite062009 |
| signal transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| molecular transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| receptor activity | 2.39311927684508 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 2.37122853419919 | bayes_pls_golite062009 |
| protein binding | 2.276111749106 | bayes_pls_golite062009 |
| tubulin binding | 2.18641675163967 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 2.16831387024372 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.12615078788254 | bayes_pls_golite062009 |
| receptor signaling protein activity | 2.10379226653669 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 1.9016235206634 | bayes_pls_golite062009 |
| microtubule binding | 1.88110801192607 | bayes_pls_golite062009 |
| actin binding | 1.87817875565699 | bayes_pls_golite062009 |
| acetylcholine receptor activator activity | 1.83545227594542 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 1.82515074380651 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.81249386965144 | bayes_pls_golite062009 |
| molecular adaptor activity | 1.81145713371725 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| insulin receptor substrate binding | 1.62657794525303 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 1.6084489855403 | bayes_pls_golite062009 |
| SH3/SH2 adaptor activity | 1.59474164216385 | bayes_pls_golite062009 |
| transcription regulator activity | 1.56748951434625 | bayes_pls_golite062009 |
| JUN kinase kinase kinase kinase activity | 1.55257528159541 | bayes_pls_golite062009 |
| DNA binding | 1.35333135345112 | bayes_pls_golite062009 |
| kinase binding | 1.26086833316556 | bayes_pls_golite062009 |
| ErbB-3 class receptor binding | 1.25765701903393 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| nucleic acid binding | 1.16049201286103 | bayes_pls_golite062009 |
| transporter activity | 1.11833481501707 | bayes_pls_golite062009 |
| transcription factor activity | 1.10928254946881 | bayes_pls_golite062009 |
| protein kinase binding | 1.06030596516506 | bayes_pls_golite062009 |
| cation channel activity | 1.04999722123563 | bayes_pls_golite062009 |
| ErbB-2 class receptor binding | 1.02996109010965 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.97575992765505 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.959360414036299 | bayes_pls_golite062009 |
| growth factor binding | 0.86076618871384 | bayes_pls_golite062009 |
| protein binding, bridging | 0.83823250804321 | bayes_pls_golite062009 |
| MAP kinase activity | 0.81943579965027 | bayes_pls_golite062009 |
| actin filament binding | 0.794152600084 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.705905455086486 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase regulator activity | 0.688047400629641 | bayes_pls_golite062009 |
| vinculin binding | 0.666656406096231 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.612883428421652 | bayes_pls_golite062009 |
| transcription repressor activity | 0.568332175782799 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| enzyme binding | 0.46284745266176 | bayes_pls_golite062009 |
| protein kinase C activity | 0.41587987561486 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 0.35402045013148 | bayes_pls_golite062009 |
| phosphotyrosine binding | 0.311079584914389 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 0.287189255116606 | bayes_pls_golite062009 |
| channel activity | 0.287189255116606 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.267404531445803 | bayes_pls_golite062009 |
| insulin receptor binding | 0.266450215230107 | bayes_pls_golite062009 |
| substrate-specific channel activity | 0.261869836686301 | bayes_pls_golite062009 |
| ion channel activity | 0.241519346930618 | bayes_pls_golite062009 |
| protein complex binding | 0.239339759110451 | bayes_pls_golite062009 |
| insulin receptor activity | 0.237134032032089 | bayes_pls_golite062009 |
| SH2 domain binding | 0.226760162354251 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 0.20643152368029 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 0.20643152368029 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity, type I | 0.0506751594607393 | bayes_pls_golite062009 |
| MAP kinase kinase kinase kinase activity | 0.01826424351081 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.0040394359628233 | bayes_pls_golite062009 |
|
Region A: Residues: [397-453] |
1 11 21 31 41 51
| | | | | |
1 APFIPKVKNA MDTSNISKEF VEIQIDPSSL APQQLAVTHR DHDFENFTFV DTNRVLV
|
| Detection Method: | |
| Confidence: | 93.39794 |
| Match: | 1mrvA |
| Description: | crystal structure of an inactive Akt2 kinase domain |
Matching Structure (courtesy of the PDB): |
|
