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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Lap4. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 7 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
AMS1
  • vacuolar membrane
  • carbohydrate metabolic process
  • oligosaccharide catabolic process
  • alpha-mannosidase activity
  • BIK1
  • spindle microtubule
  • cell cortex
  • spindle pole body
  • spindle
  • condensed nuclear chromosome kinetochore
  • kinetochore
  • mitotic spindle elongation
  • mitotic anaphase B
  • mitotic spindle organization in nucleus
  • karyogamy involved in conjugation with cellular fusion
  • microtubule binding
  • CPR1
  • nucleus
  • mitochondrion
  • histone deacetylase complex
  • ascospore formation
  • protein metabolic process
  • peptidyl-prolyl cis-trans isomerase activity
  • HHT1, HHT2
  • nucleus
  • nuclear nucleosome
  • chromosome
  • replication fork protection complex
  • nucleosome
  • mitotic cell cycle spindle assembly checkpoint
  • DNA repair
  • negative regulation of biosynthetic process
  • chromatin assembly or disassembly
  • positive regulation of transcription
  • response to DNA damage stimulus
  • aging
  • DNA packaging
  • nucleosome assembly
  • negative regulation of transposition, RNA-mediated
  • chromosome organization
  • negative regulation of transcription
  • negative regulation of transposition
  • regulation of transposition
  • regulation of transposition, RNA-mediated
  • DNA binding
  • HTB1
  • nuclear nucleosome
  • chromatin assembly or disassembly
  • postreplication repair
  • DNA binding
  • LAP4
  • fungal-type vacuole
  • vacuolar protein catabolic process
  • aminopeptidase I activity
  • VMA4
  • vacuolar proton-transporting V-type ATPase, V1 domain
  • fungal-type vacuole membrane
  • vacuolar acidification
  • proton-transporting ATPase activity, rotational mechanism
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    nuclear nucleosome 6.966E-5 7 12 2 6292
    nucleosome 6.966E-5 7 12 2 6292
    nuclear chromosome part 8.6733E-4 7 190 3 6292
    vacuole 1.1455E-3 7 209 3 6292
    nuclear chromosome 1.4752E-3 7 228 3 6292
    protein-DNA complex 1.6447E-3 7 57 2 6292
    chromosomal part 1.6505E-3 7 237 3 6292
    replication fork protection complex 2.224E-3 7 2 1 6292
    chromosome 2.509E-3 7 274 3 6292
    nuclear chromatin 2.6853E-3 7 73 2 6292
    chromatin 2.9834E-3 7 77 2 6292
    vacuolar membrane 6.3297E-3 7 113 2 6292
    vacuolar part 7.231E-3 7 121 2 6292
    proton-transporting V-type ATPase, V1 domain 8.8705E-3 7 8 1 6292
    vacuolar proton-transporting V-type ATPase, V1 domain 8.8705E-3 7 8 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    chromatin assembly or disassembly 6.2038E-4 7 35 2 6292
    negative regulation of transposition, RNA-mediated 1.1125E-3 7 1 1 6292
    regulation of transposition, RNA-mediated 1.1125E-3 7 1 1 6292
    mitosis 5.3832E-3 7 104 2 6292
    nuclear division 5.5873E-3 7 106 2 6292
    organelle fission 6.3297E-3 7 113 2 6292
    mitotic anaphase B 6.6592E-3 7 6 1 6292
    oligosaccharide catabolic process 7.7654E-3 7 7 1 6292
    anaphase 7.7654E-3 7 7 1 6292
    mitotic anaphase 7.7654E-3 7 7 1 6292
    M phase of mitotic cell cycle 8.0653E-3 7 128 2 6292
    negative regulation of transposition 9.9746E-3 7 9 1 6292
    regulation of transposition 9.9746E-3 7 9 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    alpha-mannosidase activity 1.1125E-3 7 1 1 6292
    aminopeptidase I activity 1.1125E-3 7 1 1 6292
    mannosidase activity 4.4437E-3 7 4 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle