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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 3 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

holo TFIIH complex 2.8918E-9 3 10 3 6292
DNA-directed RNA polymerase II, holoenzyme 6.6801E-7 3 56 3 6292
transcription factor complex 1.3774E-6 3 71 3 6292
nucleoplasm part 5.8345E-5 3 245 3 6292
nucleoplasm 7.3064E-5 3 264 3 6292
nuclear lumen 3.709E-4 3 453 3 6292
organelle lumen 1.1495E-3 3 660 3 6292
intracellular organelle lumen 1.1495E-3 3 660 3 6292
membrane-enclosed lumen 1.3717E-3 3 700 3 6292
nucleotide-excision repair factor 3 complex 3.3344E-3 3 7 1 6292
nuclear part 5.3751E-3 3 1103 3 6292
protein complex 5.8881E-3 3 1137 3 6292
nucleotide-excision repair complex 9.9809E-3 3 21 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

transcription initiation from RNA polymerase II promoter 3.9076E-7 3 47 3 6292
transcription initiation 7.4359E-7 3 58 3 6292
negative regulation of transcription from RNA polymerase II promoter, mitotic 4.2416E-6 3 8 2 6292
regulation of transcription from RNA polymerase II promoter, mitotic 4.2416E-6 3 8 2 6292
regulation of transcription, mitotic 5.4528E-6 3 9 2 6292
negative regulation of transcription, mitotic 5.4528E-6 3 9 2 6292
protein complex biogenesis 1.4668E-5 3 155 3 6292
protein complex assembly 1.4668E-5 3 155 3 6292
regulation of transcription from RNA polymerase II promoter 4.698E-5 3 228 3 6292
macromolecular complex assembly 8.8168E-5 3 281 3 6292
transcription from RNA polymerase II promoter 1.4965E-4 3 335 3 6292
macromolecular complex subunit organization 1.8121E-4 3 357 3 6292
regulation of transcription, DNA-dependent 1.8274E-4 3 358 3 6292
regulation of RNA metabolic process 1.9053E-4 3 363 3 6292
regulation of transcription 2.2565E-4 3 384 3 6292
cellular component assembly 2.2742E-4 3 385 3 6292
negative regulation of transcription from RNA polymerase II promoter 2.6665E-4 3 60 2 6292
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.85E-4 3 415 3 6292
regulation of nitrogen compound metabolic process 2.8707E-4 3 416 3 6292
regulation of gene expression 3.5155E-4 3 445 3 6292
regulation of macromolecule biosynthetic process 3.7833E-4 3 456 3 6292
regulation of cellular biosynthetic process 4.1966E-4 3 472 3 6292
regulation of biosynthetic process 4.2234E-4 3 473 3 6292
regulation of macromolecule metabolic process 4.639E-4 3 488 3 6292
transcription, DNA-dependent 5.081E-4 3 503 3 6292
RNA biosynthetic process 5.2344E-4 3 508 3 6292
regulation of primary metabolic process 5.4224E-4 3 514 3 6292
regulation of cellular metabolic process 6.1504E-4 3 536 3 6292
regulation of metabolic process 6.5376E-4 3 547 3 6292
transcription 6.7188E-4 3 552 3 6292
cellular component biogenesis 1.3367E-3 3 694 3 6292
negative regulation of transcription, DNA-dependent 1.8258E-3 3 157 2 6292
negative regulation of RNA metabolic process 1.849E-3 3 158 2 6292
negative regulation of transcription 1.9912E-3 3 164 2 6292
negative regulation of gene expression 1.9912E-3 3 164 2 6292
regulation of cellular process 2.0181E-3 3 796 3 6292
regulation of biological process 2.2389E-3 3 824 3 6292
negative regulation of macromolecule biosynthetic process 2.2655E-3 3 175 2 6292
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.3959E-3 3 180 2 6292
negative regulation of nitrogen compound metabolic process 2.3959E-3 3 180 2 6292
negative regulation of biosynthetic process 2.6396E-3 3 189 2 6292
negative regulation of cellular biosynthetic process 2.6396E-3 3 189 2 6292
negative regulation of macromolecule metabolic process 2.7234E-3 3 192 2 6292
nucleotide-excision repair, DNA duplex unwinding 2.8585E-3 3 6 1 6292
negative regulation of cellular metabolic process 3.2225E-3 3 209 2 6292
negative regulation of metabolic process 3.2531E-3 3 210 2 6292
RNA metabolic process 3.4763E-3 3 954 3 6292
negative regulation of cellular process 4.5939E-3 3 250 2 6292
negative regulation of biological process 4.7035E-3 3 253 2 6292
cellular macromolecule biosynthetic process 6.7003E-3 3 1187 3 6292
macromolecule biosynthetic process 6.7343E-3 3 1189 3 6292
biological regulation 7.1507E-3 3 1213 3 6292
gene expression 8.4626E-3 3 1283 3 6292
DNA geometric change 9.5071E-3 3 20 1 6292
DNA duplex unwinding 9.5071E-3 3 20 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

general RNA polymerase II transcription factor activity 1.004E-6 3 64 3 6292
RNA polymerase II transcription factor activity 8.6215E-6 3 130 3 6292
transcription regulator activity 1.5509E-4 3 339 3 6292
protein kinase regulator activity 1.5615E-4 3 46 2 6292
kinase regulator activity 1.7737E-4 3 49 2 6292
RNA polymerase II carboxy-terminal domain kinase activity 4.768E-4 3 1 1 6292
cyclin-dependent protein kinase activating kinase activity 9.5344E-4 3 2 1 6292
enzyme regulator activity 3.1616E-3 3 207 2 6292
cyclin-dependent protein kinase activity 3.8101E-3 3 8 1 6292
protein kinase activator activity 4.2857E-3 3 9 1 6292
kinase activator activity 4.7611E-3 3 10 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle