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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 6 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
IOC3
  • ISW1 complex
    		•
  • chromatin remodeling
    		•
  • protein binding
    		•
    ISW1
  • ISW1 complex
    		•
  • chromatin remodeling
  • RNA elongation
    		•
  • ATPase activity
    		•
    ITC1
  • chromatin accessibility complex
    		•
  • negative regulation of transcription from RNA polymerase II promoter by pheromones
  • chromatin remodeling
  • chromatin silencing at telomere
    		•
  • molecular_function
    		•
    MOT1
  • mitochondrion
  • nuclear chromosome
  • nuclear outer membrane
    		•
  • transcription of nuclear rRNA large RNA polymerase I transcript
  • regulation of RNA polymerase II transcriptional preinitiation complex assembly
  • regulation of transcription from RNA polymerase II promoter
    		•
  • ATPase activity
  • rDNA binding
  • TATA-binding protein binding
    		•
    RSC8
  • nucleus
  • RSC complex
    		•
  • ATP-dependent chromatin remodeling
  • double-strand break repair via nonhomologous end joining
    		•
  • DNA-dependent ATPase activity
    		•
    VPS1
  • membrane fraction
  • peroxisome
  • cytoplasm
  • mitochondrial outer membrane
    		•
  • protein retention in Golgi apparatus
  • peroxisome organization
  • vacuolar transport
  • protein targeting to vacuole
  • actin cytoskeleton organization
    		•
  • GTPase activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    chromatin remodeling complex 8.4468E-7 6 99 4 6292
    ISWI complex 4.5436E-6 6 4 2 6292
    ISW1 complex 4.5436E-6 6 4 2 6292
    nuclear part 8.4241E-4 6 1103 5 6292
    intracellular organelle part 2.2664E-3 6 2282 6 6292
    organelle part 2.2664E-3 6 2282 6 6292
    chromatin accessibility complex 3.8098E-3 6 4 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    chromatin remodeling 1.842E-7 6 68 4 6292
    chromatin modification 7.0577E-6 6 168 4 6292
    chromatin organization 1.5002E-5 6 203 4 6292
    cellular component organization 2.5085E-4 6 1582 6 6292
    chromosome organization 7.7766E-4 6 555 4 6292
    organelle organization 9.3483E-4 6 1127 5 6292
    RNA polymerase II transcriptional preinitiation complex assembly 9.5359E-4 6 1 1 6292
    regulation of RNA polymerase II transcriptional preinitiation complex assembly 9.5359E-4 6 1 1 6292
    transcription of nuclear rRNA large RNA polymerase I transcript 9.5359E-4 6 1 1 6292
    regulation of transcription initiation from RNA polymerase II promoter 9.5359E-4 6 1 1 6292
    transcriptional preinitiation complex assembly 9.5359E-4 6 1 1 6292
    rRNA transcription 2.8585E-3 6 3 1 6292
    negative regulation of transcription from RNA polymerase II promoter by pheromones 3.8098E-3 6 4 1 6292
    negative regulation of gene-specific transcription from RNA polymerase II promoter 3.8098E-3 6 4 1 6292
    negative regulation of gene-specific transcription 3.8098E-3 6 4 1 6292
    negative regulation of transcription by pheromones 3.8098E-3 6 4 1 6292
    transcription, DNA-dependent 8.4571E-3 6 503 3 6292
    RNA biosynthetic process 8.6959E-3 6 508 3 6292
    gene-specific transcription from RNA polymerase II promoter 9.5019E-3 6 10 1 6292
    regulation of transcription by pheromones 9.5019E-3 6 10 1 6292
    regulation of transcription from RNA polymerase II promoter by pheromones 9.5019E-3 6 10 1 6292
    cellular response to pheromone 9.5019E-3 6 10 1 6292
    regulation of gene-specific transcription from RNA polymerase II promoter 9.5019E-3 6 10 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    nucleoside-triphosphatase activity 1.0128E-4 6 329 4 6292
    hydrolase activity, acting on acid anhydrides 1.3355E-4 6 353 4 6292
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.3355E-4 6 353 4 6292
    pyrophosphatase activity 1.3355E-4 6 353 4 6292
    ATPase activity 6.8999E-4 6 211 3 6292
    TATA-binding protein binding 1.9064E-3 6 2 1 6292
    hydrolase activity 5.1329E-3 6 911 4 6292
    rDNA binding 6.6592E-3 6 7 1 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle