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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.084] [SVM Score: 0.436043521882]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
ISW2
  • nucleus
  • chromatin accessibility complex
    		•
  • negative regulation of transcription from RNA polymerase II promoter by pheromones
  • chromatin remodeling
  • nucleosome positioning
  • chromatin silencing at telomere
    		•
  • ATPase activity
    		•
    ITC1
  • chromatin accessibility complex
    		•
  • negative regulation of transcription from RNA polymerase II promoter by pheromones
  • chromatin remodeling
  • chromatin silencing at telomere
    		•
  • molecular_function
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    chromatin accessibility complex 3.0316E-7 2 4 2 6292
    chromatin remodeling complex 2.4511E-4 2 99 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    negative regulation of transcription from RNA polymerase II promoter by pheromones 3.0316E-7 2 4 2 6292
    negative regulation of gene-specific transcription from RNA polymerase II promoter 3.0316E-7 2 4 2 6292
    negative regulation of gene-specific transcription 3.0316E-7 2 4 2 6292
    negative regulation of transcription by pheromones 3.0316E-7 2 4 2 6292
    regulation of transcription from RNA polymerase II promoter by pheromones 2.2737E-6 2 10 2 6292
    gene-specific transcription from RNA polymerase II promoter 2.2737E-6 2 10 2 6292
    cellular response to pheromone 2.2737E-6 2 10 2 6292
    regulation of transcription by pheromones 2.2737E-6 2 10 2 6292
    regulation of gene-specific transcription from RNA polymerase II promoter 2.2737E-6 2 10 2 6292
    regulation of gene-specific transcription 5.3053E-6 2 15 2 6292
    cellular response to organic substance 9.6001E-6 2 20 2 6292
    chromatin silencing at telomere 7.5032E-5 2 55 2 6292
    negative regulation of transcription from RNA polymerase II promoter 8.9432E-5 2 60 2 6292
    chromatin remodeling 1.151E-4 2 68 2 6292
    response to pheromone 2.3525E-4 2 97 2 6292
    negative regulation of gene expression, epigenetic 2.5011E-4 2 100 2 6292
    chromatin silencing 2.5011E-4 2 100 2 6292
    gene silencing 2.5011E-4 2 100 2 6292
    regulation of gene expression, epigenetic 2.5011E-4 2 100 2 6292
    cellular response to chemical stimulus 2.8654E-4 2 107 2 6292
    response to organic substance 4.7071E-4 2 137 2 6292
    negative regulation of transcription, DNA-dependent 6.1875E-4 2 157 2 6292
    negative regulation of RNA metabolic process 6.2668E-4 2 158 2 6292
    negative regulation of gene expression 6.7534E-4 2 164 2 6292
    negative regulation of transcription 6.7534E-4 2 164 2 6292
    chromatin modification 7.0879E-4 2 168 2 6292
    negative regulation of macromolecule biosynthetic process 7.6927E-4 2 175 2 6292
    negative regulation of nitrogen compound metabolic process 8.1399E-4 2 180 2 6292
    negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 8.1399E-4 2 180 2 6292
    negative regulation of biosynthetic process 8.9766E-4 2 189 2 6292
    negative regulation of cellular biosynthetic process 8.9766E-4 2 189 2 6292
    negative regulation of macromolecule metabolic process 9.2646E-4 2 192 2 6292
    nucleosome positioning 9.5344E-4 2 3 1 6292
    chromatin organization 1.036E-3 2 203 2 6292
    negative regulation of cellular metabolic process 1.0983E-3 2 209 2 6292
    negative regulation of metabolic process 1.1088E-3 2 210 2 6292
    regulation of transcription from RNA polymerase II promoter 1.3075E-3 2 228 2 6292
    negative regulation of cellular process 1.5726E-3 2 250 2 6292
    negative regulation of biological process 1.6107E-3 2 253 2 6292
    transcription from RNA polymerase II promoter 2.8267E-3 2 335 2 6292
    regulation of transcription, DNA-dependent 3.2288E-3 2 358 2 6292
    regulation of RNA metabolic process 3.3198E-3 2 363 2 6292
    cellular response to stimulus 3.6193E-3 2 379 2 6292
    response to chemical stimulus 3.6769E-3 2 382 2 6292
    regulation of transcription 3.7155E-3 2 384 2 6292
    regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 4.3405E-3 2 415 2 6292
    regulation of nitrogen compound metabolic process 4.3615E-3 2 416 2 6292
    regulation of gene expression 4.9915E-3 2 445 2 6292
    regulation of macromolecule biosynthetic process 5.2416E-3 2 456 2 6292
    regulation of cellular biosynthetic process 5.6164E-3 2 472 2 6292
    regulation of biosynthetic process 5.6402E-3 2 473 2 6292
    regulation of macromolecule metabolic process 6.004E-3 2 488 2 6292
    chromatin assembly 6.0308E-3 2 19 1 6292
    transcription, DNA-dependent 6.3792E-3 2 503 2 6292
    RNA biosynthetic process 6.5067E-3 2 508 2 6292
    regulation of primary metabolic process 6.6615E-3 2 514 2 6292
    regulation of cellular metabolic process 7.2445E-3 2 536 2 6292
    regulation of metabolic process 7.5452E-3 2 547 2 6292
    transcription 7.6839E-3 2 552 2 6292
    chromosome organization 7.7677E-3 2 555 2 6292
    nucleosome organization 9.1975E-3 2 29 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
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