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View Protein Complex Details

Complex Overview

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ACT1
  • cellular bud neck contractile ring
  • NuA4 histone acetyltransferase complex
  • Swr1 complex
  • Ino80 complex
  • actin filament
  • actin cortical patch
  • histone acetyltransferase complex
  • DNA repair
  • contractile ring contraction involved in cell cycle cytokinesis
  • vesicle transport along actin filament
  • response to osmotic stress
  • cellular cell wall organization
  • cytokinesis
  • endocytosis
  • exocytosis
  • protein secretion
  • chronological cell aging
  • regulation of transcription from RNA polymerase II promoter
  • mitochondrion inheritance
  • ascospore formation
  • vacuole inheritance
  • establishment of mitotic spindle orientation
  • response to oxidative stress
  • budding cell isotropic bud growth
  • histone acetylation
  • actin filament reorganization involved in cell cycle
  • structural constituent of cytoskeleton
  • ADH1
  • cytosol
  • fermentation
  • NADH oxidation
  • ethanol biosynthetic process involved in glucose fermentation to ethanol
  • alcohol dehydrogenase (NAD) activity
  • ARP4
  • nucleus
  • nuclear chromatin
  • NuA4 histone acetyltransferase complex
  • Swr1 complex
  • Ino80 complex
  • DNA repair
  • chromatin remodeling
  • regulation of transcription, DNA-dependent
  • histone acetylation
  • chromatin organization
  • regulation of transcription from RNA polymerase II promoter
  • histone acetyltransferase activity
  • ATP-dependent 5'-3' DNA helicase activity
  • chromatin binding
  • ARP8
  • nucleus
  • Ino80 complex
  • biological_process
  • ATP-dependent 5'-3' DNA helicase activity
  • ESC8
  • nucleus
  • chromatin silencing
  • molecular_function
  • IES1
  • nucleus
  • Ino80 complex
  • chromatin remodeling
  • molecular_function
  • IES5
  • nucleus
  • biological_process
  • molecular_function
  • INO80
  • Ino80 complex
  • DNA repair
  • chromatin remodeling
  • transcription from RNA polymerase II promoter
  • ATPase activity
  • ATP-dependent 5'-3' DNA helicase activity
  • IOC3
  • ISW1 complex
  • chromatin remodeling
  • protein binding
  • ISW1
  • ISW1 complex
  • chromatin remodeling
  • RNA elongation
  • ATPase activity
  • ISW2
  • nucleus
  • chromatin accessibility complex
  • negative regulation of transcription from RNA polymerase II promoter by pheromones
  • chromatin remodeling
  • nucleosome positioning
  • chromatin silencing at telomere
  • ATPase activity
  • ITC1
  • chromatin accessibility complex
  • negative regulation of transcription from RNA polymerase II promoter by pheromones
  • chromatin remodeling
  • chromatin silencing at telomere
  • molecular_function
  • MOT1
  • mitochondrion
  • nuclear chromosome
  • nuclear outer membrane
  • transcription of nuclear rRNA large RNA polymerase I transcript
  • regulation of RNA polymerase II transcriptional preinitiation complex assembly
  • regulation of transcription from RNA polymerase II promoter
  • ATPase activity
  • rDNA binding
  • TATA-binding protein binding
  • NHP10
  • nucleus
  • Ino80 complex
  • chromatin remodeling
  • molecular_function
  • NPL6
  • nucleus
  • RSC complex
  • chromatin remodeling
  • protein import into nucleus
  • ATP-dependent chromatin remodeling
  • telomere maintenance
  • response to DNA damage stimulus
  • DNA-dependent ATPase activity
  • RPC40
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • ribosome biogenesis
  • DNA-directed RNA polymerase activity
  • RSC2
  • RSC complex
  • sister chromatid cohesion
  • ATP-dependent chromatin remodeling
  • telomere maintenance
  • double-strand break repair via nonhomologous end joining
  • DNA-dependent ATPase activity
  • RSC4
  • RSC complex
  • ATP-dependent chromatin remodeling
  • DNA-dependent ATPase activity
  • RSC58
  • RSC complex
  • chromatin remodeling
  • molecular_function
  • RSC6
  • RSC complex
  • ATP-dependent chromatin remodeling
  • DNA-dependent ATPase activity
  • RSC8
  • nucleus
  • RSC complex
  • ATP-dependent chromatin remodeling
  • double-strand break repair via nonhomologous end joining
  • DNA-dependent ATPase activity
  • RVB2
  • nucleus
  • Swr1 complex
  • Ino80 complex
  • nuclear outer membrane
  • chromatin remodeling complex
  • chromatin remodeling
  • snoRNA metabolic process
  • regulation of transcription from RNA polymerase II promoter
  • ATPase activity
  • ATP-dependent 5'-3' DNA helicase activity
  • SIN3
  • Sin3 complex
  • histone deacetylase complex
  • negative regulation of transcription from RNA polymerase II promoter
  • chromatin silencing at rDNA
  • telomere maintenance
  • double-strand break repair via nonhomologous end joining
  • histone deacetylation
  • chromatin silencing at silent mating-type cassette
  • positive regulation of transcription from RNA polymerase II promoter
  • chromatin silencing at telomere
  • transcription coactivator activity
  • histone deacetylase activity
  • transcription corepressor activity
  • VPS1
  • membrane fraction
  • peroxisome
  • cytoplasm
  • mitochondrial outer membrane
  • protein retention in Golgi apparatus
  • peroxisome organization
  • vacuolar transport
  • protein targeting to vacuole
  • actin cytoskeleton organization
  • GTPase activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    chromatin remodeling complex 8.6322E-29 24 99 18 6292
    DNA helicase complex 1.4654E-15 24 11 7 6292
    Ino80 complex 1.4654E-15 24 11 7 6292
    nuclear part 3.3731E-12 24 1103 20 6292
    RSC complex 5.8628E-11 24 20 6 6292
    protein complex 1.1338E-10 24 1137 19 6292
    nuclear chromatin 1.406E-10 24 73 8 6292
    chromatin 2.1809E-10 24 77 8 6292
    nucleus 2.1433E-9 24 2041 22 6292
    macromolecular complex 7.3447E-8 24 1635 19 6292
    nuclear chromosome 7.4895E-8 24 228 9 6292
    nuclear chromosome part 2.9E-7 24 190 8 6292
    intracellular organelle part 3.0321E-7 24 2282 21 6292
    organelle part 3.0321E-7 24 2282 21 6292
    chromosome 3.6333E-7 24 274 9 6292
    chromosomal part 1.5704E-6 24 237 8 6292
    Swr1 complex 2.1535E-5 24 15 3 6292
    membrane-bounded organelle 7.6796E-5 24 3771 23 6292
    intracellular membrane-bounded organelle 7.6796E-5 24 3771 23 6292
    chromatin accessibility complex 8.3283E-5 24 4 2 6292
    ISWI complex 8.3283E-5 24 4 2 6292
    ISW1 complex 8.3283E-5 24 4 2 6292
    intracellular organelle 3.9856E-4 24 4070 23 6292
    organelle 4.0066E-4 24 4071 23 6292
    H4/H2A histone acetyltransferase complex 1.234E-3 24 14 2 6292
    NuA4 histone acetyltransferase complex 1.234E-3 24 14 2 6292
    non-membrane-bounded organelle 1.6426E-3 24 959 10 6292
    intracellular non-membrane-bounded organelle 1.6426E-3 24 959 10 6292
    intracellular part 2.9448E-3 24 4938 24 6292
    intracellular 3.5241E-3 24 4975 24 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    chromatin remodeling 7.4872E-25 24 68 15 6292
    chromatin modification 2.322E-22 24 168 17 6292
    chromatin organization 6.4731E-21 24 203 17 6292
    chromosome organization 1.8117E-13 24 555 17 6292
    organelle organization 1.4446E-9 24 1127 18 6292
    ATP-dependent chromatin remodeling 3.2318E-8 24 26 5 6292
    cellular component organization 4.1247E-8 24 1582 19 6292
    transcription, DNA-dependent 7.3152E-7 24 503 11 6292
    RNA biosynthetic process 8.0825E-7 24 508 11 6292
    transcription 1.8587E-6 24 552 11 6292
    cellular response to stimulus 5.5259E-6 24 379 9 6292
    regulation of transcription from RNA polymerase II promoter 1.5285E-5 24 228 7 6292
    response to DNA damage stimulus 1.9146E-5 24 236 7 6292
    transcription from RNA polymerase II promoter 2.0612E-5 24 335 8 6292
    regulation of transcription, DNA-dependent 3.3395E-5 24 358 8 6292
    regulation of RNA metabolic process 3.6916E-5 24 363 8 6292
    regulation of transcription 5.5326E-5 24 384 8 6292
    DNA repair 6.3502E-5 24 192 6 6292
    cellular response to stress 7.2237E-5 24 290 7 6292
    negative regulation of transcription from RNA polymerase II promoter by pheromones 8.3283E-5 24 4 2 6292
    negative regulation of gene-specific transcription from RNA polymerase II promoter 8.3283E-5 24 4 2 6292
    negative regulation of gene-specific transcription 8.3283E-5 24 4 2 6292
    negative regulation of transcription by pheromones 8.3283E-5 24 4 2 6292
    regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 9.6199E-5 24 415 8 6292
    regulation of nitrogen compound metabolic process 9.7853E-5 24 416 8 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.023E-4 24 1566 15 6292
    double-strand break repair via nonhomologous end joining 1.0617E-4 24 25 3 6292
    nucleic acid metabolic process 1.5482E-4 24 1415 14 6292
    regulation of gene expression 1.5729E-4 24 445 8 6292
    regulation of macromolecule biosynthetic process 1.8656E-4 24 456 8 6292
    regulation of cellular biosynthetic process 2.3712E-4 24 472 8 6292
    regulation of biosynthetic process 2.4063E-4 24 473 8 6292
    non-recombinational repair 2.7006E-4 24 34 3 6292
    regulation of macromolecule metabolic process 2.9857E-4 24 488 8 6292
    RNA metabolic process 3.4206E-4 24 954 11 6292
    regulation of primary metabolic process 4.262E-4 24 514 8 6292
    cellular nitrogen compound metabolic process 4.52E-4 24 1770 15 6292
    negative regulation of gene expression, epigenetic 4.9995E-4 24 100 4 6292
    gene silencing 4.9995E-4 24 100 4 6292
    regulation of gene expression, epigenetic 4.9995E-4 24 100 4 6292
    chromatin silencing 4.9995E-4 24 100 4 6292
    nitrogen compound metabolic process 5.1988E-4 24 1791 15 6292
    regulation of cellular metabolic process 5.6658E-4 24 536 8 6292
    gene-specific transcription from RNA polymerase II promoter 6.1594E-4 24 10 2 6292
    regulation of transcription from RNA polymerase II promoter by pheromones 6.1594E-4 24 10 2 6292
    cellular response to pheromone 6.1594E-4 24 10 2 6292
    regulation of gene-specific transcription from RNA polymerase II promoter 6.1594E-4 24 10 2 6292
    regulation of transcription by pheromones 6.1594E-4 24 10 2 6292
    regulation of metabolic process 6.4984E-4 24 547 8 6292
    chromatin silencing at telomere 1.1234E-3 24 55 3 6292
    double-strand break repair 1.2466E-3 24 57 3 6292
    response to stimulus 1.3375E-3 24 766 9 6292
    regulation of gene-specific transcription 1.4205E-3 24 15 2 6292
    negative regulation of transcription from RNA polymerase II promoter 1.4471E-3 24 60 3 6292
    response to stress 1.9423E-3 24 497 7 6292
    cellular macromolecule biosynthetic process 2.2926E-3 24 1187 11 6292
    macromolecule biosynthetic process 2.3252E-3 24 1189 11 6292
    cellular response to organic substance 2.5408E-3 24 20 2 6292
    negative regulation of transcription, DNA-dependent 2.685E-3 24 157 4 6292
    negative regulation of RNA metabolic process 2.7477E-3 24 158 4 6292
    biological regulation 2.7477E-3 24 1213 11 6292
    negative regulation of transcription 3.1454E-3 24 164 4 6292
    negative regulation of gene expression 3.1454E-3 24 164 4 6292
    regulation of RNA polymerase II transcriptional preinitiation complex assembly 3.8144E-3 24 1 1 6292
    regulation of transcription initiation from RNA polymerase II promoter 3.8144E-3 24 1 1 6292
    RNA polymerase II transcriptional preinitiation complex assembly 3.8144E-3 24 1 1 6292
    transcription of nuclear rRNA large RNA polymerase I transcript 3.8144E-3 24 1 1 6292
    transcriptional preinitiation complex assembly 3.8144E-3 24 1 1 6292
    negative regulation of macromolecule biosynthetic process 3.9742E-3 24 175 4 6292
    covalent chromatin modification 4.3268E-3 24 88 3 6292
    histone modification 4.3268E-3 24 88 3 6292
    gene expression 4.3599E-3 24 1283 11 6292
    negative regulation of nitrogen compound metabolic process 4.396E-3 24 180 4 6292
    negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 4.396E-3 24 180 4 6292
    DNA metabolic process 4.9119E-3 24 585 7 6292
    negative regulation of biosynthetic process 5.2303E-3 24 189 4 6292
    negative regulation of cellular biosynthetic process 5.2303E-3 24 189 4 6292
    negative regulation of macromolecule metabolic process 5.5306E-3 24 192 4 6292
    transcription from RNA polymerase I promoter 5.6833E-3 24 30 2 6292
    regulation of cellular process 7.2332E-3 24 796 8 6292
    negative regulation of cellular metabolic process 7.4542E-3 24 209 4 6292
    negative regulation of metabolic process 7.5795E-3 24 210 4 6292
    monohydric alcohol biosynthetic process 7.6148E-3 24 2 1 6292
    vesicle transport along actin filament 7.6148E-3 24 2 1 6292
    actin filament-based movement 7.6148E-3 24 2 1 6292
    ethanol biosynthetic process involved in glucose fermentation to ethanol 7.6148E-3 24 2 1 6292
    ethanol biosynthetic process 7.6148E-3 24 2 1 6292
    histone acetylation 8.1171E-3 24 36 2 6292
    biosynthetic process 8.291E-3 24 1602 12 6292
    regulation of biological process 8.9095E-3 24 824 8 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    DNA-dependent ATPase activity 1.7777E-13 24 55 9 6292
    ATPase activity 2.8148E-12 24 211 12 6292
    nucleoside-triphosphatase activity 2.5654E-11 24 329 13 6292
    hydrolase activity, acting on acid anhydrides 6.2527E-11 24 353 13 6292
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 6.2527E-11 24 353 13 6292
    pyrophosphatase activity 6.2527E-11 24 353 13 6292
    ATPase activity, coupled 1.7767E-9 24 149 9 6292
    ATP-dependent 5'-3' DNA helicase activity 5.657E-9 24 7 4 6292
    5'-3' DNA helicase activity 1.1285E-8 24 8 4 6292
    ATP-dependent DNA helicase activity 4.8092E-7 24 18 4 6292
    hydrolase activity 7.6837E-7 24 911 14 6292
    DNA helicase activity 6.9972E-6 24 34 4 6292
    ATP-dependent helicase activity 2.8329E-5 24 48 4 6292
    purine NTP-dependent helicase activity 2.8329E-5 24 48 4 6292
    helicase activity 2.4468E-4 24 83 4 6292
    catalytic activity 1.1437E-3 24 2150 16 6292
    TATA-binding protein binding 7.6148E-3 24 2 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle