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Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate. Catalysis of the reaction: ATP + H2O = ADP + phosphate, driving the unwinding of the DNA helix. Catalysis of the unwinding of the DNA helix of DNA containing four-way junctions, including Holliday junctions. Catalysis of the reaction: NTP + H2O = NDP + phosphate to drive the unwinding of a DNA or RNA helix. Catalysis of the unwinding of the DNA helix in the direction 5' to 3'. Catalysis of the unwinding of the DNA helix in the direction 3' to 5'. Catalysis of the reaction: NTP + H2O = NDP + phosphate to drive the unwinding of a DNA helix.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: DNA helicase activity
Acc: GO:0003678
Aspect: Molecular Function
Desc: Catalysis of the reaction: NTP + H2O = NDP + phosphate to drive the unwinding of a DNA helix.
Synonyms:
  • GO:0003679
Proteins in PDR annotated with:
   This term: 101 [Search]
   Term or descendants: 388 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0003678 - DNA helicase activity (interactive image map)

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