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Protein Overview: SPCC550.03c

General Information:
Name(s) found: SPCC550.03c [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
SHOW ALL
  • RNA helicase involved in mRNA catabolism [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1213 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [ISSLink to PubMed article]
    Ski complex [ISS]
    cytosol [IDALink to PubMed article]
    nucleolus [ISSLink to PubMed article]
    Biological Process: regulation of translation [ISSLink to PubMed article]
    mRNA catabolic process [ISSLink to PubMed article]
    Molecular Function: ATP binding [IEA]
    RNA helicase activity [ISSLink to PubMed article]
    ATP-dependent helicase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSKLVDAIN EVAVSNKDKI ELDGIKDDSF DGHLSITEAT YDVDTFLKPS PALSKDWIRK  60
   61 LQKKWDREIT YKGLYEYPET LARTQIRFQR HGLEGKIMGY KEVPELIEDL NSKNSSSFLR 120
  121 KPSSKNEFVR GSTSNIPFLA DDSDVDAIAG EPSVKMALYG EDGLLQVPPG FSRGLSMTAT 180
  181 STTDNLNDEF DPEKWDTKKV KSSNRNFVTI HELNEHLKNV NSKHSEIDDL LPDKRSIVSL 240
  241 PPSTLNLHKQ PDYAHVVDSS APIENFQQLV PEMALDFPFE LDNFQKEAIY HLEMGDSVFV 300
  301 AAHTSAGKTV VAEYAIALAQ KHMTKAIYTS PIKALSNQKF RDFKHKFEDV GILTGDVQVN 360
  361 PEGSCLLMTT EILRSMLYRG ADLIRDVEFV IFDEVHYVND LERGVVWEEV IIMLPPHVTL 420
  421 ILLSATVPNT KEFASWVGRT KKKNIYVIST LKRPVPLEHY LWVKQNMFKI VDQHGRFLMD 480
  481 GYKSANDALK KPDKPVIAKD NKNSARGRGA ARGRGVQTNM MRGRGSAKSV ERRDANTWVH 540
  541 LIGHLHKQNL LPVIVFVFSK KRCEEYVDTL TNRDLNNHQE KSEVHVVIEK AVARLKKEDR 600
  601 LLPQIGRMRE MLSRGLAVHH GGLLPIIKEI VEILFQRGLV KVLFATETFA MGVNMPAKSV 660
  661 VFSGTQKHDG RNFRDLLPGE YTQCSGRAGR RGLDVTGTVI ILSRSELPDT ASLRHMIMGP 720
  721 SSKLISQFRL TYNMILNLLR VETLRIEDMI KRSFSENVNQ TLVPQHEEKI KSFEEKLSAL 780
  781 KKEMSDVDLK EIKSCLLSSE SFKEYTKKMH FRAITTANGK RIFKDGRVIV FQQLDFTRTV 840
  841 GVLLGTSIRT NASDCTLEVA YLNPQNNLKR PSDLLAFADA FNDVYDNAIF DESNQFKYGL 900
  901 INLSGIERVC NTILRIDSGG IRDRRGGAFR KLSEQFASIK KFSDLLFEEV NWSKVRDFEF 960
  961 CEAFEKRNFL QNKLSGNPII STPNFLTHFA LAYQEYELES NIDNLSSYIS DQNLELLPDY1020
 1021 EQRIKVLQEL GYIDAERTVL LKGRVACEIN STSELVLTEL ILENSLADFS CEETIALLSA1080
 1081 FVFDEKTEVE PTISPHLQKG KEMILSVAEK VNQIQEHYQV LYFNEGNDFE SQPRFGLMEV1140
 1141 CYEWARGMSF NRITDLTDVL EGSIVRTIIR LDEVLRECRG AARVVGDSSM YTKMEECQNL1200
 1201 IRRNIVFCPS LYM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..200] deduced N/A No confident structure predictions are available.
    2 View Details [201..260] PSI-BLAST 60.69897 No description for 2db3A was found.
    3 View Details [261..523] PSI-BLAST 23.0 No description for 2p6rA was found.
    4 View Details [524..588] PSI-BLAST 16.0 No description for 2p6nA was found.
    5 View Details [589..824] PSI-BLAST 7.0 Nucleotide excision repair enzyme UvrB
    6 View Details [825..1126] PSI-BLAST 32.69897 No description for 2q0zX was found.
    7 View Details [1127..1213] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • nucleoside-triphosphatase activity
    		•  2.95079405147356 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.87427509025394 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.85499564954033 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.85178667290149 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • transporter activity
    		•  2.58140740499725 bayes_pls_golite062009
  • hydrolase activity
    		•  2.55157966585974 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.39695871109024 bayes_pls_golite062009
  • ATPase activity
    		•  2.39535714892224 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  2.18396165590908 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.11222585187695 bayes_pls_golite062009
  • DNA binding
    		•  1.7904783386531 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.68903321260301 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.47858140861683 bayes_pls_golite062009
  • RNA helicase activity
    		•  1.42791449104435 bayes_pls_golite062009
  • RNA-dependent ATPase activity
    		•  1.39335733374328 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
    		•  1.36724390116598 bayes_pls_golite062009
  • motor activity
    		•  1.34881124154297 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.29730375126024 bayes_pls_golite062009
  • protein binding
    		•  1.22129154759482 bayes_pls_golite062009
    		• 1.15596552553878 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.929901285538132 bayes_pls_golite062009
  • nucleotide binding
    		•  0.922442819194247 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.920987930180051 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.920926158369519 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.906554174337376 bayes_pls_golite062009
  • structural molecule activity
    		•  0.86514677273731 bayes_pls_golite062009
  • RNA binding
    		•  0.715902454627085 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.712344060953362 bayes_pls_golite062009
  • helicase activity
    		•  0.6191010101321 bayes_pls_golite062009
  • transcription factor activity
    		•  0.603758349693077 bayes_pls_golite062009
  • GTPase activity
    		•  0.437665353870877 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.434775387083003 bayes_pls_golite062009
  • ligase activity
    		•  0.417681194526243 bayes_pls_golite062009
  • ATP binding
    		•  0.41092997612902 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.385813421701492 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.377870145186619 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.355466224802969 bayes_pls_golite062009
  • microtubule motor activity
    		•  0.32730260506261 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  0.29664013896754 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  0.29664013896754 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  0.296406132096546 bayes_pls_golite062009
  • GTP binding
    		•  0.295705904888768 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.294474570607914 bayes_pls_golite062009
  • translation regulator activity
    		•  0.29096092258568 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  0.29028316917561 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.282352478532746 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.274994961137851 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.220608508617331 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.219533217661421 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.219157471322311 bayes_pls_golite062009
  • microfilament motor activity
    		•  0.10236059675512 bayes_pls_golite062009
  • protein transporter activity
    		•  0.0397092337273124 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.0254369227200564 bayes_pls_golite062009
    4 No functions predicted.
    5
    Term Confidence Notes
  • nucleoside-triphosphatase activity
    		•  2.95079405147356 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.87427509025394 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.85499564954033 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.85178667290149 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • transporter activity
    		•  2.58140740499725 bayes_pls_golite062009
  • hydrolase activity
    		•  2.55157966585974 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.39695871109024 bayes_pls_golite062009
  • ATPase activity
    		•  2.39535714892224 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  2.18396165590908 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.11222585187695 bayes_pls_golite062009
  • DNA binding
    		•  1.7904783386531 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.68903321260301 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.47858140861683 bayes_pls_golite062009
  • RNA helicase activity
    		•  1.42791449104435 bayes_pls_golite062009
  • RNA-dependent ATPase activity
    		•  1.39335733374328 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
    		•  1.36724390116598 bayes_pls_golite062009
  • motor activity
    		•  1.34881124154297 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.29730375126024 bayes_pls_golite062009
  • protein binding
    		•  1.22129154759482 bayes_pls_golite062009
    		• 1.15596552553878 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.929901285538132 bayes_pls_golite062009
  • nucleotide binding
    		•  0.922442819194247 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.920987930180051 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.920926158369519 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.906554174337376 bayes_pls_golite062009
  • structural molecule activity
    		•  0.86514677273731 bayes_pls_golite062009
  • RNA binding
    		•  0.715902454627085 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.712344060953362 bayes_pls_golite062009
  • helicase activity
    		•  0.6191010101321 bayes_pls_golite062009
  • transcription factor activity
    		•  0.603758349693077 bayes_pls_golite062009
  • GTPase activity
    		•  0.437665353870877 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.434775387083003 bayes_pls_golite062009
  • ligase activity
    		•  0.417681194526243 bayes_pls_golite062009
  • ATP binding
    		•  0.41092997612902 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.385813421701492 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.377870145186619 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.355466224802969 bayes_pls_golite062009
  • microtubule motor activity
    		•  0.32730260506261 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  0.29664013896754 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  0.29664013896754 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  0.296406132096546 bayes_pls_golite062009
  • GTP binding
    		•  0.295705904888768 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.294474570607914 bayes_pls_golite062009
  • translation regulator activity
    		•  0.29096092258568 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  0.29028316917561 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.282352478532746 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.274994961137851 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.220608508617331 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.219533217661421 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.219157471322311 bayes_pls_golite062009
  • microfilament motor activity
    		•  0.10236059675512 bayes_pls_golite062009
  • protein transporter activity
    		•  0.0397092337273124 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.0254369227200564 bayes_pls_golite062009
    6
    Term Confidence Notes
  • RNA-dependent ATPase activity
    		•  3.40791872038512 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
    		•  3.40070584403887 bayes_pls_golite062009
  • RNA helicase activity
    		•  3.25446655280881 bayes_pls_golite062009
    		• 3.01111645480862 bayes_pls_golite062009
  • binding
    		•  2.65544526722793 bayes_pls_golite062009
  • protein binding
    		•  2.55331587515144 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.00003070639929 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  1.96155856210682 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  1.94268098951022 bayes_pls_golite062009
  • transporter activity
    		•  1.94143938635343 bayes_pls_golite062009
  • ATPase activity
    		•  1.94063929259701 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.93031967085303 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.91231918357992 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.90999409453671 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.89711816247783 bayes_pls_golite062009
  • helicase activity
    		•  1.87693598354249 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  1.87127651162653 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  1.87127651162653 bayes_pls_golite062009
  • cation channel activity
    		•  1.84843298243351 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  1.82318341284761 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  1.81839281588293 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  1.81742923395177 bayes_pls_golite062009
  • potassium channel activity
    		•  1.81257297770622 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.81071289575882 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.76281327097473 bayes_pls_golite062009
  • ion channel activity
    		•  1.70663166559662 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.70274134661261 bayes_pls_golite062009
  • gated channel activity
    		•  1.68818168029572 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.66007375521419 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  1.65899897018442 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  1.65208263051952 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  1.63616928632474 bayes_pls_golite062009
  • channel activity
    		•  1.63616928632474 bayes_pls_golite062009
  • structural molecule activity
    		•  1.59238444054212 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  1.52401313013637 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  1.32367033892557 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  1.32367033892557 bayes_pls_golite062009
  • actin binding
    		•  1.32092343528021 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.24469346535998 bayes_pls_golite062009
  • hydrolase activity
    		•  0.524040950977088 bayes_pls_golite062009
  • inward rectifier potassium channel activity
    		•  0.43450134854604 bayes_pls_golite062009
    7 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle