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Protein Overview: GVP36

General Information:
Name(s) found: GVP36 / YIL041W [SGD]
Description(s) found:
Found 29 descriptions.
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  • BAR domain-containing protein that localizes to both early and late Golgi vesicles; required for adaptation to varying nutrient concentrations, fluid-phase endocytosis, polarization of the actin cytoskeleton, and vacuole biogenesis [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 326 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    integral to Golgi membrane [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFNAFASSL SKKLQEISTS VSEKTQELPS LAQSTQRMVQ ERLGQVTDIS QLPREYTELE  60
   61 DKVDTIKLIY NHFLGVTAIY ENGSYDYPKY INESVNEFSR SVASKLTELT HATSASEAQN 120
  121 ILVAPGPIKE PKTLNYALSK VALNSSECLN KMFPTEEQPL ASALLQFSDV QAKIAQARIQ 180
  181 QDTLIQTKFN KNLRERLSFE IGKADKCRKD VHSMRLRYDV ARTNLANNKK PEKEASLRVQ 240
  241 METLEDQFAQ VTEDATVCLQ EVISHANFSE DLKELAKAQA EYFETSAGLM KEFLSNSFAE 300
  301 EPEAKPEVAE EEKPQTAISM NDEDDA

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) CPR7 GBP2 GVP36 HHO1 HPR1 HRB1 MFT1 SUB2 TEX1 THO2 THP2 ULS1 YNL140C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run TOR1 No Comments Reinke A, et al. (2004)
    View Run LST8 No Comments Reinke A, et al. (2004)
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run MLP2 #16 Mitotic-New search criteria Keck JM, et al. (2011)
    View Run None Entered #18 Mitotic Prep4-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data GVP36 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..113] deduced N/A No confident structure predictions are available.
    2 View Details [114..326] ORFEUS 7.91 Arfaptin, Rac-binding fragment

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.2879693624429 bayes_pls_golite062009
  • protein binding
    		•  2.08046860800611 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.02414077739262 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.067852352497379 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.0314833132263769 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.0230779033512197 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.0199119414909105 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle