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Protein Overview: ULS1

General Information:
Name(s) found: ULS1 / YOR191W [SGD]
Description(s) found:
Found 27 descriptions.
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  • RING finger protein involved in proteolytic control of sumoylated substrates; interacts with SUMO (Smt3p); member of the SWI/SNF family of DNA-dependent ATPases; plays a role in antagonizing silencing during mating-type switching [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 1619 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IPILink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed article]
    Biological Process: chromatin assembly or disassembly [IGILink to PubMed article][IMPLink to PubMed article][IPILink to PubMed article]
    mating type switching [IMPLink to PubMed article]
    Molecular Function: DNA-dependent ATPase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAVPTIDLT LADSDNEDIF HSFSSSTSVD KIDIRKENGK LRMAGLEVAQ SNDDAARQAF  60
   61 HVFKTNISNN ETFDTILSKS KTITDSTFNN EKSSNEVKQQ QVLKEETMGS SNDEKKTQES 120
  121 SPSAEMIKLF YENDDVPLSD SFKQKEEGKR INQDEQVKEN ICGISSSYVS KDYDGVEDDF 180
  181 EPNTCQDSNL DFQEEKLNLN NKPSQQQFSD PETKDNSLKS ENKDQIKGVT TTSYRDLPIE 240
  241 SSAFQDSETQ NNSKNTIPNI VNEKRTPALP SNLSSVESSL KNETAKVEGK TTVRLPGLQN 300
  301 NVALLEQEQS ELFKHFSEQP VDISDFGRKI KRKHSGDFAD NKILKRPILP SKNMDHTTHN 360
  361 SHDSEQKNSS IIILSDEDES GAGINDIESP LKVSEPNTAD ALRSSVPEVI SLLDLPNIDL 420
  421 NNSVIKEASG SNSIPTSETD AQSSSSSVLQ GTIMTEQATQ SSQHECNSSL DTLKKNHQKL 480
  481 LKDLNSRESE LRNALSCCKT NSEILRRKLS RREKEVSDAE KHWQLLLTSM ARGGRTISST 540
  541 QQILVDEAEN QLNKLKEKRQ LTKSKLDSIN LKMYNYNEQW KSFVHSKNIN LQKSLAALER 600
  601 SARDSKASAT VNKRNECLAE KEKLDQMLKE GTLSFSTYKQ LTGEIQQKLN DLKLGDQRTT 660
  661 DINSVLPIVR QPLAKRDLFI KSIDTAKDLL AKNTSRTEMT KRILYRHLDN LVSYKNFFED 720
  721 GRSLIDINRR HVAHESAQIL FTNGVKMPIV FETLQDYGIK FSNPAIVNPD RRAQYFKSIE 780
  781 VARDLISKST RSEDAKRKIT RFLNIIEEFR KDIDTGFPPT PLKREGVGKA VVGLRQQGLK 840
  841 MDRLYENLRR YKIPITSEEL LQQSYLFPVN ADQRPPSNWN IVENTEDTSS TANDLSMQDE 900
  901 FHISNMHAAE DQEQIRALLE NVKQSESIID GEALTPEDMT VNLLKHQRLG LHWLLQVENS 960
  961 AKKGGLLADD MGLGKTIQAI ALMLANRSEE SKCKTNLIVA PVSVLRVWKG ELETKVKKRA1020
 1021 KFTTFIFGGS GNGKVKHWRD LARYDAVLVS YQTLANEFKK HWPKKLDGEQ NQLPAVPHIQ1080
 1081 ALNRLKTSNE YYSPFFCNDS TFYRILLDEG QNIKNKNTRA SKACCTINGM YRWVLSGTPI1140
 1141 QNSMDELYSL IRFLRIPPYH KEQRFKLDIG RFFQRNKQYQ YDNEDRKNAL RKVRVLLNAI1200
 1201 MLRRSKADKI DGKPLLELPP KIVEVDESRL KGEELKFYTA LESKNQALAK KLLNNSTRGS1260
 1261 YSSVLTLLLR LRQACCHSEL VVMGEKKAEG TKVANGKSFE DDWLRLYYKI THMSGEAQAQ1320
 1321 VITSMNSMTC FWCMEQLEPE AMSVLTGCGH LICDTCIEPF IEESSMLPQA KKTKGGAFAI1380
 1381 PCKDCQRLTN EKDIVSHKLY DQVINQGFTE EDLHAEYLSE MEKQKIQQKN VYVPNFESLE1440
 1441 PSTKIEQCIQ VIQRVFDESA TEKIIIFSQF TTFFEILEHF LKNKLNFPYL KYIGSMNAQR1500
 1501 RSDVINEFYR DPEKRILLIS MKAGNSGLTL TCANHVVIVD PFWNPYVEEQ AQDRCYRISQ1560
 1561 TKKVQVHKLF IKDSVEDRIS ELQKRKKEMV DSAMDPGKIK EVNSLGRREL GFLFGLNAL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) CPR7 GBP2 GVP36 HHO1 HPR1 HRB1 MFT1 SUB2 TEX1 THO2 THP2 ULS1 YNL140C
    View Details Ho Y, et al. (2002) ATG7 NOP2 TIF6 ULS1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data ULS1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..91] deduced N/A No confident structure predictions are available.
    2 View Details [92..438] PSI-BLAST 40.0 Heavy meromyosin subfragment
    3 View Details [439..631] PSI-BLAST 4.522879 No description for 2dfsA was found.
    4 View Details [632..922] deduced N/A No confident structure predictions are available.
    5 View Details [923..1442] PSI-BLAST 80.522879 Sulfolobus solfataricus SWI2/SNF2 ATPase core in complex with dsDNA
    6 View Details [1443..1619] PSI-BLAST 57.30103 Sulfolobus solfataricus SWI2/SNF2 ATPase C-terminal domain


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle