Protein Overview: CBP2

General Information:
Name(s) found:	CBP2 / YHL038C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|729059\|sp\|P03874.2\|CBP2_YEAST RecName: Full=Cytochrome B pre-mRNA-processing protein 2 [NCBI NR] gi\|6321749\|ref\|NP_011825.1\| Mitochondrial protein required for splicing of the group I intron aI5 of the COB pre-mRNA, binds to the RNA to promote splicing; also involved in but not essential for splicing of the COB bI2 intron and the intron in the 21S rR [NCBI NR] pir\|\|BWBY CBP2 protein - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|2289867\|gb\|AAB65050.1\| cytochrome B pre-mRNA processing protein 2 [Saccharomyces cerevisiae] [NCBI NR] Cytochrome B pre-mRNA-processing protein 2 OS=Saccharomyces cerevisiae GN=CBP2 PE=1 SV=2 [Swiss-Prot] CBP2 Apo-cytochrome b pre-mRNA processing protein 2 [mips] Mitochondrial protein required for splicing of the group I intron aI5 of the COB pre-mRNA, binds to the RNA to promote splicing; also involved in but not essential for splicing of the COB bI2 intron and the intron in the 21S rRNA gene [SGD] CBP2, Chr VIII from 23614-25506, reverse complement [yeast_orfs2] Chr VIII from 23614-25506, reverse complement [yeastorf3.fasta] Chr VIII from 25506-23614, reverse complement [yeastorf5.fasta] (P03874) Cytochrome B pre-mRNA processing protein 2 [4932.FASTACCERV.txt] CBP2 SGDID:S0001030, Chr VIII from 25506-23614, reverse complement, Verified ORF [yeastflysequest.fasta] Cbp2p [Saccharomyces cerevisiae]gi\|729059\|sp\|P03874\|CBP2_YEAST Cytochrome B pre-mRNA processing protein 2gi\|625345\|pir\|\|BWBY CBP2 protein - yeast (Saccharomyces cerevisiae)gi\|2289867\|gb\|AAB65050.1\| Cytochrome B pre-mRNA processing protein 2 [Saccharomy [nrdb_11152004_Chlamydomonas] CBP2 SGDID:S000001030, Chr VIII from 25506-23614, reverse complement, Verified ORF, "Mitochondrial protein required for splicing of the group I intron aI5 of the COB pre-mRNA, binds to the RNA to promote splicing; also involved in but not essential for sp [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] cytochrome B pre-mRNA processing protein 2 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Cytochrome B pre-mRNA-processing protein 2 [nr-271106-contam.fasta] Mitochondrial protein required for splicing of the group I intron aI5 of the COB pre-mRNA, binds to the RNA to promote splicing; also involved in but not essential for splicing of the COB bI2 intron and the intron in the 21S rRNA gene; Cbp2p [Saccharomyce [nr-271106-contam.fasta] CBP2 SGDID:S000001030, Chr VIII from 25506-23614, reverse complement, Verified ORF, "Mitochondrial protein required for splicing of the group I intron aI5 of the COB pre-mRNA, binds to the RNA to promote splicing; also involved in but not essential for splicing of the COB bI2 intron and the intron in the 21S rRNA gene" [yeast-bovrabprots.fasta] [chemostatdb.fasta] Cytochrome B pre-mRNA-processing protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CBP2 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] CBP2 SGDID:S000001030, Chr VIII from 25509-23617, Genome Release 64-1-1, reverse complement, Verified ORF, "Mitochondrial protein required for splicing of the group I intron aI5 of the COB pre-mRNA, binds to the RNA to promote splicing; also involved in but not essential for splicing of the COB bI2 intron and the intron in the 21S rRNA gene" [yeast-030211-contam.fasta] CBP2 SGDID:S000001030, Chr VIII from 25509-23617, Genome Release 64-2-1, reverse complement, Verified ORF, "Required for splicing of the group I intron bI5 of the COB pre-mRNA; nuclear-encoded mitochondrial protein that binds to the RNA to promote splicing; also involved in but not essential for splicing of the COB bI2 intron and the intron in the 21S rRNA gene" [20141208_orf_trans.fasta] YHL038C SGDID:S000001030, Chr VIII from 25509-23617, Genome Release 64-1-1, reverse complement, Verified ORF, "Mitochondrial protein required for splicing of the group I intron aI5 of the COB pre-mRNA, binds to the RNA to promote splicing; also involved in but not essential for splicing of the COB bI2 intron and the intron in the 21S rRNA gene" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	630 amino acids
Gene Ontology:
Cellular Component:	mitochondrion [IDA]
Biological Process:	Group I intron splicing [IDA]
Molecular Function:	RNA binding [IDA][IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVNWQTLFMV SLRRQGSSSR YRYKFNMENI THQVFPRCKQ AFKKTNLSYE YCDLEGVLYN  60
   61 ISLTDLQKLL LRDINAPREH AFKIVRTDLT QKSSKKRIQH WERIAPMFDH PLSLYEKLFS 120
  121 EMDEDFKPSF EWQQLIRVRC KDDKLKLQRV IWPKSIFSNF CRGIGVKKST YDRLLEQNNG 180
  181 EVPMFVNPAN AKPLPLFQVS DEAMIGEFDG IGIFPYFVDK HREFFVTEVD KLKTKIASPL 240
  241 CTLNERKRIE KANAGRILAN EEGKPFYLDA NSATTRIAGG NVVTLKQLLE RSVSHKTLWS 300
  301 KQSNKDRTCP GDILRATILS NDFSIRQLRA EFCKNFILYN IFTILQRNKK SIRSFSGNDN 360
  361 APSFQFSWNV WDSYIWKQYQ ETESMKIPTD QASLINYKTK YDSFLHDLQT YSALVISEMK 420
  421 WNQFSIFQND ETTLSRFEHI TLILQTVLTK SKMIRIFQPN LYKFMQDDLR PTLMELVGFT 480
  481 ESINATIEPG FANEQSLQSA NGLKKLANQL LYFEQEIYGE KFRVNRPIQL RPITLSANYK 540
  541 IVILDKKNAI PEIFQTLLKF MTQITTYFVK DLSEVELHGH MHCIDKKMLD KSKFMYLYEE 600
  601 KSNEEVKAAS PQKEKIVDNI IGLLSNDEEH

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	(MIPS) Mewes HW, et al. (2004)		CBP1 CBP2 CBS1 CBS2
View Details	Ho Y, et al. (2002)		CBF5 CBP2 CCM1 CDC33 CIC1 DBP7 DRS1 ENP2 ERB1 GBP2 HAS1 HMO1 HTB1 HTB2 IMD1 IMD3 ISA1 KAP95 KRE33 KRI1 KRR1 MGM101 MNP1 MSS116 NOC2 NOP12 NOP2 NOP58 NOP6 NOP7 NPL3 NUG1 PET127 POL5 PRP43 PUF6 PWP1 RLI1 RPF2 RRP12 RRP5 TIF1, TIF2 TIF4631 TIF6 TRA1 TSR1 URB1 URB2 UTP10 UTP20 YPP1 YRA1 YTM1
View Details	Qiu et al. (2008)		BI4 CBP2

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	TID3	No Comments	Cheeseman IM, et al. (2002)
View Run	MLP2	#12 Mitotic Prep1-TiO2 Flowthrough	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	KAP104	CBP2	1	Unpublished Fields Lab Data
View Screen	PTC4	CBP2	1	Unpublished Fields Lab Data
View Screen	RRB1	CBP2	1	Unpublished Fields Lab Data

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

	PROTEIN(S)	PUBLICATION
View Data	CBP2	Huh WK, et al. (2003)
View Data	CBP2	Huh WK, et al. (2003)

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..630]	ORFEUS	7.95	Reovirus polymerase lambda3

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.85

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2