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Protein Overview: BI4

General Information:
Name(s) found: BI4 / Q0120 [SGD]
Description(s) found:
Found 24 descriptions.
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  • Mitochondrial mRNA maturase, forms a complex with Nam2p to mediate splicing of the bI4 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 638 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    Biological Process: Group I intron splicing [IDALink to PubMed article][IMPLink to PubMed article]
    Molecular Function: RNA binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFRKSNVYL SLVNSYIIDS PQPSSINYWW NMGSLLGLCL VIQIVTGIFM AMHYSSNIEL  60
   61 AFSSVEHIMR DVHNGYILRY LHANGASFFF MVMFMHMAKG LYYGSYRSPR VTLWNVGVII 120
  121 FILTIATAFL GYCCVYGQMS HWGATVITNL FSAIPFVGND IVSWLWGGFS VSNPTIQRFF 180
  181 ALHYLVPFII AAMVIMHLMA LHIHGSSNPL GITGNLDRIP MHSYFIFKDL VTVFLFMLIL 240
  241 ALFVFYSPNT LGQNMALLLI TYVINILCAV CWKSLFIKYQ WKIYNKTTYY FIIQNILNTK 300
  301 QLNNFVLKFN WTKQYNKMNI VSDLFNPNRV KYYYKEDNQQ VTNMNSSNTH LTSNKKNLLV 360
  361 DTSETTRTTK NKFNYLLNIF NMKKMNQIIT KRHYSIYKDS NIRFNQWLAG LIDGDGYFCI 420
  421 TKNKYASCEI TVELKDEKML RQIQDKFGGS VKLRSGVKAI RYRLQNKEGM IKLINAVNGN 480
  481 IRNSKRLVQF NKVCILLNID FKEPIKLTKD NAWFMGFFDA DGTINYYYSG KLKIRPQLTI 540
  541 SVTNKYLHDV EYYREVFGGN IYFDKAKNGY FKWSINNKEL HNIFYTYNKS CPSKSNKGKR 600
  601 LFLIDKFYYL YDLLAFKAPH NTALYKAWLK FNEKWNNN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) BI4 CBP6 MRS1 MRS2 MRS3 MRS4 MSS1 MSS116 MSS18 MTF2 NAM2 PET54 TIM10
    View Details Qiu et al. (2008) AI2 BI3 BI4 CBP2 MRS1 MRS3 MSS18 NAM2 PET54

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..371] PSI-BLAST 99.0 Mitochondrial cytochrome b subunit, C-terminal domain; Mitochondrial cytochrome b subunit, N-terminal domain
    2 View Details [372..638] PSI-BLAST 29.522879 The structure and DNA recognition of a bifunctional homing endonuclease and group I intron splicing factor

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity
    		•  9.40961255429881 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  7.91754205622571 bayes_pls_golite062009
  • oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
    		•  7.25948538109776 bayes_pls_golite062009
  • ubiquinol-cytochrome-c reductase activity
    		•  7.25948538109776 bayes_pls_golite062009
  • oxidoreductase activity, acting on diphenols and related substances as donors
    		•  6.7552101145891 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  6.2092870783393 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  5.7873765619132 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  5.68072183887254 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  5.3015608578326 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  5.25342386319285 bayes_pls_golite062009
  • electron carrier activity
    		•  3.68085167315889 bayes_pls_golite062009
  • transporter activity
    		•  3.45764306673522 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.38637995472629 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.37175230596465 bayes_pls_golite062009
  • formate dehydrogenase activity
    		•  2.95356847428734 bayes_pls_golite062009
  • NADH dehydrogenase activity
    		•  2.90322961223579 bayes_pls_golite062009
  • electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity
    		•  2.45338123687772 bayes_pls_golite062009
  • catalytic activity
    		•  1.19342057724506 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  1.03512868485178 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  0.930306906058772 bayes_pls_golite062009
  • binding
    		•  0.774901332897627 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.486633405379917 bayes_pls_golite062009
  • RNA binding
    		•  0.451720554693503 bayes_pls_golite062009
  • protein binding
    		•  0.404482007264961 bayes_pls_golite062009
    2
    Term Confidence Notes
  • hydrogen ion transmembrane transporter activity
    		•  4.86957814307046 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  3.19396515742363 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  3.14137318623419 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  3.13129165629404 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.87584421861632 bayes_pls_golite062009
  • proton-transporting ATPase activity, rotational mechanism
    		•  2.72106737769483 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  2.45692795980719 bayes_pls_golite062009
  • nuclease activity
    		•  1.8823587130277 bayes_pls_golite062009
  • transporter activity
    		•  1.53150861647153 bayes_pls_golite062009
  • cation-transporting ATPase activity
    		•  1.48236450952558 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions
    		•  1.44877785586913 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.3410831520534 bayes_pls_golite062009
  • endonuclease activity
    		•  1.19235582394343 bayes_pls_golite062009
  • hydrolase activity
    		•  1.19000863380989 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.14667639205171 bayes_pls_golite062009
  • catalytic activity
    		•  1.00294942392567 bayes_pls_golite062009
  • binding
    		•  0.947409481120466 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.92351380308588 bayes_pls_golite062009
  • RNA binding
    		•  0.910353314690524 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.861094108940112 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.661074037502297 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.654163274985902 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.641683221108629 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.623124237163431 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.619595196929581 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.619567263202566 bayes_pls_golite062009
  • DNA binding
    		•  0.571084560404215 bayes_pls_golite062009
  • endodeoxyribonuclease activity
    		•  0.49074473960659 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  0.35748048504687 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.320782703157868 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.277037132264983 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.266347160384031 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.263794771362707 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  0.222918604925639 bayes_pls_golite062009
  • ATPase activity
    		•  0.0799898712397951 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle