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View Structure Prediction Details

Protein: BI4
Organism: Saccharomyces cerevisiae
Length: 638 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BI4.

Description E-value Query
Range		 Subject
Range
gi|12407264 - gi|12407264|dbj|BAB21403.1| cytochrome b [Eleotris oxycephala]
 522.0 [0..2] [378..3]

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Predicted Domain #1
Region A:
Residues: [1-371] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFRKSNVYL SLVNSYIIDS PQPSSINYWW NMGSLLGLCL VIQIVTGIFM AMHYSSNIEL  60
   61 AFSSVEHIMR DVHNGYILRY LHANGASFFF MVMFMHMAKG LYYGSYRSPR VTLWNVGVII 120
  121 FILTIATAFL GYCCVYGQMS HWGATVITNL FSAIPFVGND IVSWLWGGFS VSNPTIQRFF 180
  181 ALHYLVPFII AAMVIMHLMA LHIHGSSNPL GITGNLDRIP MHSYFIFKDL VTVFLFMLIL 240
  241 ALFVFYSPNT LGQNMALLLI TYVINILCAV CWKSLFIKYQ WKIYNKTTYY FIIQNILNTK 300
  301 QLNNFVLKFN WTKQYNKMNI VSDLFNPNRV KYYYKEDNQQ VTNMNSSNTH LTSNKKNLLV 360
  361 DTSETTRTTK N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 99.0
Match: 1ezvC
Description: Mitochondrial cytochrome b subunit, C-terminal domain; Mitochondrial cytochrome b subunit, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity 9.40961255429881 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 7.91754205622571 bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor 7.25948538109776 bayes_pls_golite062009
ubiquinol-cytochrome-c reductase activity 7.25948538109776 bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors 6.7552101145891 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 6.2092870783393 bayes_pls_golite062009
cation transmembrane transporter activity 5.7873765619132 bayes_pls_golite062009
ion transmembrane transporter activity 5.68072183887254 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 5.3015608578326 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 5.25342386319285 bayes_pls_golite062009
electron carrier activity 3.68085167315889 bayes_pls_golite062009
transporter activity 3.45764306673522 bayes_pls_golite062009
substrate-specific transporter activity 3.38637995472629 bayes_pls_golite062009
transmembrane transporter activity 3.37175230596465 bayes_pls_golite062009
formate dehydrogenase activity 2.95356847428734 bayes_pls_golite062009
NADH dehydrogenase activity 2.90322961223579 bayes_pls_golite062009
electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity 2.45338123687772 bayes_pls_golite062009
catalytic activity 1.19342057724506 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 1.03512868485178 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 0.930306906058772 bayes_pls_golite062009
binding 0.774901332897627 bayes_pls_golite062009
nucleic acid binding 0.486633405379917 bayes_pls_golite062009
RNA binding 0.451720554693503 bayes_pls_golite062009
protein binding 0.404482007264961 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [372-638] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KFNYLLNIFN MKKMNQIITK RHYSIYKDSN IRFNQWLAGL IDGDGYFCIT KNKYASCEIT  60
   61 VELKDEKMLR QIQDKFGGSV KLRSGVKAIR YRLQNKEGMI KLINAVNGNI RNSKRLVQFN 120
  121 KVCILLNIDF KEPIKLTKDN AWFMGFFDAD GTINYYYSGK LKIRPQLTIS VTNKYLHDVE 180
  181 YYREVFGGNI YFDKAKNGYF KWSINNKELH NIFYTYNKSC PSKSNKGKRL FLIDKFYYLY 240
  241 DLLAFKAPHN TALYKAWLKF NEKWNNN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.522879
Match: 1p8kZ
Description: The structure and DNA recognition of a bifunctional homing endonuclease and group I intron splicing factor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrogen ion transmembrane transporter activity 4.86957814307046 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 3.19396515742363 bayes_pls_golite062009
cation transmembrane transporter activity 3.14137318623419 bayes_pls_golite062009
ion transmembrane transporter activity 3.13129165629404 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.87584421861632 bayes_pls_golite062009
proton-transporting ATPase activity, rotational mechanism 2.72106737769483 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 2.45692795980719 bayes_pls_golite062009
nuclease activity 1.8823587130277 bayes_pls_golite062009
transporter activity 1.53150861647153 bayes_pls_golite062009
cation-transporting ATPase activity 1.48236450952558 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions 1.44877785586913 bayes_pls_golite062009
transmembrane transporter activity 1.3410831520534 bayes_pls_golite062009
endonuclease activity 1.19235582394343 bayes_pls_golite062009
hydrolase activity 1.19000863380989 bayes_pls_golite062009
substrate-specific transporter activity 1.14667639205171 bayes_pls_golite062009
catalytic activity 1.00294942392567 bayes_pls_golite062009
binding 0.947409481120466 bayes_pls_golite062009
nucleic acid binding 0.92351380308588 bayes_pls_golite062009
RNA binding 0.910353314690524 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.861094108940112 bayes_pls_golite062009
primary active transmembrane transporter activity 0.661074037502297 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.654163274985902 bayes_pls_golite062009
active transmembrane transporter activity 0.641683221108629 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.623124237163431 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.619595196929581 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.619567263202566 bayes_pls_golite062009
DNA binding 0.571084560404215 bayes_pls_golite062009
endodeoxyribonuclease activity 0.49074473960659 bayes_pls_golite062009
deoxyribonuclease activity 0.35748048504687 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.320782703157868 bayes_pls_golite062009
pyrophosphatase activity 0.277037132264983 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.266347160384031 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.263794771362707 bayes_pls_golite062009
ATPase activity, coupled 0.222918604925639 bayes_pls_golite062009
ATPase activity 0.0799898712397951 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle