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Protein Overview: PET54

General Information:
Name(s) found: PET54 / YGR222W [SGD]
Description(s) found:
Found 30 descriptions.
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  • Mitochondrial inner membrane protein that binds to the 5' UTR of the COX3 mRNA to activate its translation together with Pet122p and Pet494p; also binds to the COX1 Group I intron AI5 beta to facilitate exon ligation during splicing [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 293 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial matrix [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    mitochondrial inner membrane [IDALink to PubMed article]
    Biological Process: Group I intron splicing [IGILink to PubMed article]
    translation [IMPLink to PubMed article]
    Molecular Function: translation regulator activity [IMPLink to PubMed article]
    RNA binding [NASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKASSKAIKL VLDHLKSTGR VLGSVESGNS ATISEKTASV NKQQQLQEKK PSVLQYRSYN  60
   61 PYLVKEDFLS ILPENLYKKR GQFTNELDFQ LMKVRDPKYF QFKDQYYLFF NDYNSLTEYI 120
  121 KLTKHSRINK IRVKMTPLAQ PLPTLLTKLQ RYSKNLYNAF RSSEQYFEGL NEKVDVSGEF 180
  181 TTNQLRSILD SVEEIENKSV LVWNIPTKLR SHDILNYFWF YNIRSSFKIY WDDEMKRNLR 240
  241 FISFENSHDA YRFKRNYHGL LAKELLTLSE KGDAADYSLE MDDSKILIEH LSE

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) AEP1 AEP2 BI4 CBP6 CBS1 CBS2 MRS1 MRS2 MRS3 MRS4 MSS1 MSS116 MSS18 MSS51 MTF2 NAM2 PET111 PET112 PET122 PET309 PET494 PET54 SUV3 TIM10
    View Details Qiu et al. (2008) AEP1 AEP2 BI3 BI4 CBS2 MRS1 MRS2 MSS116 NAM2 PET111 PET122 PET309 PET54 SUV3

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data PET54 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..293] deduced N/A No confident structure predictions are available.
    2 View Details [136..293] FFAS03 1.19 Solution Structure of the RNA recognition motif in RNA-binding region containing protein 1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • nucleic acid binding
    		•  3.6649737847299 bayes_pls_golite062009
  • RNA binding
    		•  3.54132281875185 bayes_pls_golite062009
  • mRNA binding
    		•  3.12096544084441 bayes_pls_golite062009
  • binding
    		•  3.05100551329453 bayes_pls_golite062009
    		• 2.65416081536729 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.20182415212933 bayes_pls_golite062009
  • DNA binding
    		•  1.06738888024145 bayes_pls_golite062009
  • protein binding
    		•  1.05805521997665 bayes_pls_golite062009
  • structural molecule activity
    		•  0.767649718525223 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  0.761573507268535 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  0.470675891495223 bayes_pls_golite062009
  • transcription factor activity
    		•  0.273768131383019 bayes_pls_golite062009
  • translation regulator activity
    		•  0.246220338604608 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.23733335659183 bayes_pls_golite062009
  • transcription factor binding
    		•  0.0848709019823142 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.0127733116412899 bayes_pls_golite062009
  • snRNA binding
    		•  0.00892689194659768 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle