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Protein Overview: GPG1

General Information:
Name(s) found: GPG1 / YGL121C [SGD]
Description(s) found:
Found 34 descriptions.
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  • Proposed gamma subunit of the heterotrimeric G protein that interacts with the receptor Gpr1p; involved in regulation of pseudohyphal growth; requires Gpb1p or Gpb2p to interact with Gpa2p; overproduction causes prion curing [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 126 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: signal transduction [IPILink to PubMed article]
    Molecular Function: signal transducer activity [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFYLSDIEEE ASAGAEPTYN FWEVLLFSNT QENLVTVVGE LHTLTDRVVH YKIEPESREV  60
   61 TATTLPSLLA LLLEKRNQAR RLYRDVLSMK MSELDWDIDD LFTQLQEELT RTDDTLSMYP 120
  121 RRRFYH

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) GPG1 SIR2 SIR3 SIR4 YLR278C
    View Details Ho Y, et al. (2002) AHA1 AHP1 ARF1 BFA1 CDC55 DCP2 DHH1 GND1 GPG1 HEF3 HTA2 HTB1 LHS1 LSM1 LSM4 LSM7 MGE1 MGT1 MKT1 PAT1 PEX19 PPE1 PPH22 RIP1 RPA135 RPB11 RTS1 RTS3 RVB1 SEC27 SOF1 TAP42 TMA19 TPD3 UBR1 YHR033W

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ZDS1 Sample 2- cpn2 from june 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen TOS8 GPG1 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..126] deduced N/A Confident ab initio structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle