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Protein Overview: QCR7

General Information:
Name(s) found: QCR7 / YDR529C [SGD]
Description(s) found:
Found 30 descriptions.
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  • Subunit 7 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; oriented facing the mitochondrial matrix; N-terminus appears to play a role in complex assembly [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 127 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    mitochondrial respiratory chain complex III [IDALink to PubMed article]
    Biological Process: respiratory chain complex III assembly [IMPLink to PubMed article]
    mitochondrial electron transport, ubiquinol to cytochrome c [IMPLink to PubMed article]
    aerobic respiration [IMPLink to PubMed article]
    Molecular Function: ubiquinol-cytochrome-c reductase activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPQSFTSIAR IGDYILKSPV LSKLCVPVAN QFINLAGYKK LGLKFDDLIA EENPIMQTAL  60
   61 RRLPEDESYA RAYRIIRAHQ TELTHHLLPR NEWIKAQEDV PYLLPYILEA EAAAKEKDEL 120
  121 DNIEVSK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) COB COR1 CYT1 QCR10 QCR2 QCR6 QCR7 QCR8 QCR9 RIP1
    View Details Ho Y, et al. (2002) QCR7 UBC4 UFD4
    View Details Qiu et al. (2008) AAC1 ATP1 ATP14 ATP15 ATP16 ATP17 ATP18 ATP2 ATP20 ATP3 ATP4 ATP5 ATP6 ATP7 ATP8 COB COR1 COX1 COX12 COX13 COX2 COX3 COX4 COX5A COX5B COX6 COX7 COX8 COX9 CYC2 CYC7 CYT1 INH1 MCR1 OLI1 QCR10 QCR2 QCR6 QCR7 QCR8 QCR9 RIP1 SDH1 SDH2 SDH3 SDH4

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data QCR7 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..127] PSI-BLAST 687.68867 14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquinol-cytochrome-c reductase activity
    		•  11.5736971809848 bayes_pls_golite062009
  • oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
    		•  11.5736971809848 bayes_pls_golite062009
  • oxidoreductase activity, acting on diphenols and related substances as donors
    		•  8.17739656377432 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  5.63908133042525 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  5.48702641896397 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  4.88973324048899 bayes_pls_golite062009
  • oxidoreductase activity
    		•  4.83598965448391 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.64530477348772 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.44988249046834 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  4.04580005556932 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.85284374888084 bayes_pls_golite062009
  • binding
    		•  1.33677693666883 bayes_pls_golite062009
  • protein binding
    		•  0.634460610267232 bayes_pls_golite062009
  • catalytic activity
    		•  0.385153095337306 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle