Protein Overview: MHR1

General Information:
Name(s) found:	MHR1 / YDR296W [SGD]
Description(s) found: Found 33 descriptions. SHOW ALL	Protein involved in homologous recombination in mitochondria; required for recombination-dependent mtDNA partitioning; involved in stimulation of mitochondrial DNA replication in response to oxidative stress [SGD]
Organism:	Saccharomyces cerevisiae
Length:	226 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] mitochondrion [IDA ]
Biological Process:	mitochondrial genome maintenance [IDA]
Molecular Function:	transcription regulator activity [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVNHSISRF RPASWFEKTK IIPPQVYIFR NLEYGQVLYS QFPNFSQTQV DKLFVRPNWS  60
   61 NRKPSLRRDI WKCMCVVNLQ NYKQSVHLYQ NLCRLRYLRD VAQRKESDKL RKKDSNGHVW 120
  121 YSGQYRPTYC QEAVADLRES LLKVFENATP AEKQTVPAKK PSIYWEDPWR MGDKDKHWNY 180
  181 DVFNALGLEH KLIQRVGNIA REESVILKEL AKLESHPTEQ TEVSSQ

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		IMG1 IMG2 MHR1 MRP20 MRP49 MRP7 MRPL1 MRPL13 MRPL15 MRPL16 MRPL17 MRPL20 MRPL22 MRPL23 MRPL24 MRPL27 MRPL28 MRPL3 MRPL35 MRPL36 MRPL39 MRPL4 MRPL44 MRPL6 MRPL7 MRPL8 MRPL9 NUG1 RTC6 YML6
View Details	Gavin AC, et al. (2006)		IMG1 MHR1 MRP49 MRPL35 MRPL8 MRPL9 YML6
View Details	Gavin AC, et al. (2002)		ATG26 BEM2 BUD3 COP1 CYR1 HRR25 IMG1 IMG2 IML1 MHR1 MRH4 MRM1 MRP20 MRP49 MRP7 MRPL1 MRPL10 MRPL13 MRPL16 MRPL17 MRPL19 MRPL20 MRPL23 MRPL24 MRPL25 MRPL27 MRPL28 MRPL3 MRPL35 MRPL36 MRPL39 MRPL4 MRPL44 MRPL51 MRPL6 MRPL7 MRPL8 NUG1 PRP43 RET2 ROM2 RTC6 SEC1 SEC26 SEC27 SIN4 SNF2 SWI3 SYP1 TAF5 UTP20 YDR115W YML6
View Details	Qiu et al. (2008)		IMG1 IMG2 MHR1 MNP1 MRP10 MRP20 MRP21 MRP4 MRP49 MRP51 MRP7 MRPL1 MRPL10 MRPL11 MRPL13 MRPL15 MRPL16 MRPL17 MRPL19 MRPL20 MRPL22 MRPL23 MRPL24 MRPL25 MRPL27 MRPL28 MRPL3 MRPL31 MRPL32 MRPL33 MRPL35 MRPL36 MRPL37 MRPL38 MRPL39 MRPL4 MRPL40 MRPL44 MRPL49 MRPL50 MRPL51 MRPL6 MRPL7 MRPL8 MRPL9 MRPS16 MRPS17 MRPS18 MRPS28 MRPS35 MRPS9 NAM9 PET123 RML2 RSM10 RSM24 RSM25 RSM27 RSM7 RTC6 YDR115W YML6

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	CMD1	MHR1	1	Unpublished Fields Lab Data
View Screen	YJR141W	MHR1	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	MHR1	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..226]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2