| Protein: | FKB65_ARATH |
| Organism: | Arabidopsis thaliana |
| Length: | 578 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FKB65_ARATH.
| Description | E-value | Query Range |
Subject Range |
|
|
394.0 | [0..1] | [578..1] |
|
Region A: Residues: [1-160] |
1 11 21 31 41 51
| | | | | |
1 MEDDFDTQNQ FPEEEPEEMD MDLPDNDEAD SAPYLKIGEE MEIGKSGLKK KLVKECEKWD 60
61 TPENGDEVEV HYTGTLLDGT KFDSSRDRGT PFKFTLGQGH VIKGWDLGIK TMKKGENAIF 120
121 TIPPELAYGE TGSPPTIPPN ATLQFDVELI AWRSVKDICG
|
| Detection Method: |  |
| Confidence: | 50.69897 |
| Match: | 1q1cA |
| Description: | Crystal structure of N(1-260) of human FKBP52 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| ryanodine-sensitive calcium-release channel activity | 10.9968443145942 | bayes_pls_golite062009 |
| intracellular ligand-gated calcium channel activity | 10.9968443145942 | bayes_pls_golite062009 |
| macrolide binding | 7.31599503004442 | bayes_pls_golite062009 |
| FK506 binding | 7.22442625476031 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 6.74926751944787 | bayes_pls_golite062009 |
| calcium channel activity | 6.4374377859142 | bayes_pls_golite062009 |
| cation channel activity | 6.06732269872248 | bayes_pls_golite062009 |
| ion channel activity | 5.45007096522107 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 5.32426176964634 | bayes_pls_golite062009 |
| channel activity | 5.32426176964634 | bayes_pls_golite062009 |
| substrate-specific channel activity | 5.28960420749143 | bayes_pls_golite062009 |
| gated channel activity | 5.28074654906904 | bayes_pls_golite062009 |
| peptidyl-prolyl cis-trans isomerase activity | 4.0615867467963 | bayes_pls_golite062009 |
| cis-trans isomerase activity | 3.99265212272703 | bayes_pls_golite062009 |
| ligand-gated channel activity | 3.34717828007833 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 3.34717828007833 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 2.6566793500337 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 2.61794461605199 | bayes_pls_golite062009 |
| calcium-release channel activity | 2.58969194870156 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 2.47257819150887 | bayes_pls_golite062009 |
| isomerase activity | 2.31710030777753 | bayes_pls_golite062009 |
| transcription regulator activity | 1.85589011277711 | bayes_pls_golite062009 |
| receptor activity | 1.78361575899771 | bayes_pls_golite062009 |
| transmembrane receptor activity | 1.7459556028988 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.68688812199737 | bayes_pls_golite062009 |
| kinase activity | 1.67904764195462 | bayes_pls_golite062009 |
| binding | 1.63170667962375 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.57898291235576 | bayes_pls_golite062009 |
| signal transducer activity | 1.53711974553033 | bayes_pls_golite062009 |
| molecular transducer activity | 1.53711974553033 | bayes_pls_golite062009 |
| protein kinase activity | 1.45320632553313 | bayes_pls_golite062009 |
| drug binding | 1.39643621593407 | bayes_pls_golite062009 |
| transferase activity | 1.34122735969662 | bayes_pls_golite062009 |
| receptor serine/threonine kinase binding | 1.32709321745178 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase binding | 1.32470025150272 | bayes_pls_golite062009 |
| transforming growth factor beta receptor binding | 1.32470025150272 | bayes_pls_golite062009 |
| transporter activity | 1.25197125648774 | bayes_pls_golite062009 |
| protein binding | 1.08765413491791 | bayes_pls_golite062009 |
| SMAD binding | 1.04905381164355 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.03909235910355 | bayes_pls_golite062009 |
| catalytic activity | 0.885282592863018 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.789390402522536 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 0.763739321802433 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 0.763739321802433 | bayes_pls_golite062009 |
| intracellular ligand-gated ion channel activity | 0.727019445105701 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.671059013500415 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.525950701946406 | bayes_pls_golite062009 |
| unfolded protein binding | 0.27473817613726 | bayes_pls_golite062009 |
| activin binding | 0.262691232876501 | bayes_pls_golite062009 |
| transcription elongation regulator activity | 0.0778721788337902 | bayes_pls_golite062009 |
|
Region A: Residues: [161-578] |
1 11 21 31 41 51
| | | | | |
1 DGGVSKKIIV EGEKWEKPKD LDEVYVKYEA RLEDGTIVGK SDGVEFTVKE GHFCPALSKA 60
61 VKTMKRGEKV LLTVKPQYGF GEFGRPASDG LQAAIPPNAT LQIDLELVSW KTVVEVTDDR 120
121 KVIKKILKEG EGYERPNEGA IVKLKLIGKL QDGTTVFVKK GHEEDEEPFE FKIDEEQVIE 180
181 GLEKAVMGMK KGEVALITIS PEYAFGSSES KQELAVIPPN STVYYEVELV SFIKEKESWD 240
241 MNTQERIEAA GKKKEEGNVL FKAGKYARAS KRYERGVKYI EYDSTFDEEE KKKSKDLKIA 300
301 CNLNDAACKL KLKDYKEAAK LSTKVLEMDS RNVKAMYRRA HAYLETADLD LAELDIKKAL 360
361 EIDPDNKEVK IEYKKLKEKV KEYNKKDAKF YSNMLSKMLE PHKGTQKEAQ AMSIDTKA
|
| Detection Method: | |
| Confidence: | 51.221849 |
| Match: | 1kt0A |
| Description: | FKBP51, C-terminal domain; FKBP51, N-terminal domains |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| intracellular ligand-gated calcium channel activity | 10.9968443145942 | bayes_pls_golite062009 |
| ryanodine-sensitive calcium-release channel activity | 10.9968443145942 | bayes_pls_golite062009 |
| macrolide binding | 7.31599503004442 | bayes_pls_golite062009 |
| FK506 binding | 7.22442625476031 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 6.74926751944787 | bayes_pls_golite062009 |
| calcium channel activity | 6.4374377859142 | bayes_pls_golite062009 |
| cation channel activity | 6.06732269872248 | bayes_pls_golite062009 |
| protein phosphatase 2A binding | 6.03345119957353 | bayes_pls_golite062009 |
| ion channel activity | 5.45007096522107 | bayes_pls_golite062009 |
| channel activity | 5.32426176964634 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 5.32426176964634 | bayes_pls_golite062009 |
| substrate-specific channel activity | 5.28960420749143 | bayes_pls_golite062009 |
| gated channel activity | 5.28074654906904 | bayes_pls_golite062009 |
| peptidyl-prolyl cis-trans isomerase activity | 4.0615867467963 | bayes_pls_golite062009 |
| cis-trans isomerase activity | 3.99265212272703 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 3.34717828007833 | bayes_pls_golite062009 |
| ligand-gated channel activity | 3.34717828007833 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 2.6566793500337 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 2.61794461605199 | bayes_pls_golite062009 |
| calcium-release channel activity | 2.58969194870156 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 2.47257819150887 | bayes_pls_golite062009 |
| phosphatase activity | 2.4502869290841 | bayes_pls_golite062009 |
| phosphoric ester hydrolase activity | 2.38923256228405 | bayes_pls_golite062009 |
| ubiquitin-protein ligase activity | 2.35894350869919 | bayes_pls_golite062009 |
| isomerase activity | 2.31710030777753 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 2.12083180880718 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 2.07186557005331 | bayes_pls_golite062009 |
| transcription regulator activity | 1.85589011277711 | bayes_pls_golite062009 |
| receptor activity | 1.78361575899771 | bayes_pls_golite062009 |
| transmembrane receptor activity | 1.7459556028988 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.68688812199737 | bayes_pls_golite062009 |
| kinase activity | 1.67904764195462 | bayes_pls_golite062009 |
| binding | 1.63170667962375 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.57898291235576 | bayes_pls_golite062009 |
| signal transducer activity | 1.53711974553033 | bayes_pls_golite062009 |
| molecular transducer activity | 1.53711974553033 | bayes_pls_golite062009 |
| phosphoprotein phosphatase activity | 1.5101001424727 | bayes_pls_golite062009 |
| protein kinase activity | 1.45320632553313 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 1.4415534360016 | bayes_pls_golite062009 |
| drug binding | 1.39643621593407 | bayes_pls_golite062009 |
| nucleic acid binding | 1.36102432998861 | bayes_pls_golite062009 |
| heat shock protein binding | 1.35268080101836 | bayes_pls_golite062009 |
| transferase activity | 1.34122735969662 | bayes_pls_golite062009 |
| receptor serine/threonine kinase binding | 1.32709321745178 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase binding | 1.32470025150272 | bayes_pls_golite062009 |
| transforming growth factor beta receptor binding | 1.32470025150272 | bayes_pls_golite062009 |
| DNA binding | 1.31957293306432 | bayes_pls_golite062009 |
| steroid hormone receptor binding | 1.26630556032955 | bayes_pls_golite062009 |
| transporter activity | 1.25197125648774 | bayes_pls_golite062009 |
| protein binding | 1.08765413491791 | bayes_pls_golite062009 |
| SMAD binding | 1.04905381164355 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.03909235910355 | bayes_pls_golite062009 |
| catalytic activity | 0.885282592863018 | bayes_pls_golite062009 |
| transcription activator activity | 0.873307397500777 | bayes_pls_golite062009 |
| transcription repressor activity | 0.841959344808827 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.789390402522536 | bayes_pls_golite062009 |
| hormone receptor binding | 0.780875583795532 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | 0.777060600234881 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 0.763739321802433 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 0.763739321802433 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 0.761034574704448 | bayes_pls_golite062009 |
| intracellular ligand-gated ion channel activity | 0.727019445105701 | bayes_pls_golite062009 |
| protein serine/threonine phosphatase activity | 0.683689287992235 | bayes_pls_golite062009 |
| transcription factor activity | 0.672036990681626 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.671059013500415 | bayes_pls_golite062009 |
| transferase activity, transferring hexosyl groups | 0.625352830428438 | bayes_pls_golite062009 |
| procollagen-proline dioxygenase activity | 0.58147873299814 | bayes_pls_golite062009 |
| peptidyl-proline 4-dioxygenase activity | 0.58147873299814 | bayes_pls_golite062009 |
| peptidyl-proline dioxygenase activity | 0.58147873299814 | bayes_pls_golite062009 |
| procollagen-proline 4-dioxygenase activity | 0.58147873299814 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.525950701946406 | bayes_pls_golite062009 |
| signal sequence binding | 0.49295886046194 | bayes_pls_golite062009 |
| enzyme binding | 0.44905827271946 | bayes_pls_golite062009 |
| superoxide-generating NADPH oxidase activity | 0.37588912752498 | bayes_pls_golite062009 |
| unfolded protein binding | 0.27473817613726 | bayes_pls_golite062009 |
| transcription factor binding | 0.273314664611729 | bayes_pls_golite062009 |
| activin binding | 0.262691232876501 | bayes_pls_golite062009 |
| hydrolase activity | 0.172906111259113 | bayes_pls_golite062009 |
| transcription elongation regulator activity | 0.0778721788337902 | bayes_pls_golite062009 |
| peroxisome targeting sequence binding | 0.0468412220974996 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor | 0.0437303095920707 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.0131115480611301 | bayes_pls_golite062009 |
