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Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. Interacting selectively and non-covalently with cyclosporin A, a cyclic undecapeptide that contains several N-methylated and unusual amino acids. Interacting selectively and non-covalently with diazepam, one of the most widely used benzodiazepine drugs. It is used as an anti-anxiety-hypnotic agent and has the proprietary name Valium. The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease. Interacting selectively and non-covalently with phenylalkylamine or any of its derivatives. Interacting selectively and non-covalently with thienylcyclohexylpiperidine. Interacting selectively and non-covalently with cocaine (2-beta-carbomethoxy-3-beta-benzoxytropane), an alkaloid obtained from dried leaves of the South American shrub Erythroxylon coca or by chemical synthesis. Interacting selectively and non-covalently with N-1-naphthylphthalamic acid, an auxin transport inhibitor. Interacting selectively and non-covalently with a macrolide, any of a large group of structurally related antibiotics produced by Streptomyces species. Interacting selectively and non-covalently with penicillin, any antibiotic that contains the condensed beta-lactamthiazolidine ring system.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: drug binding
Acc: GO:0008144
Aspect: Molecular Function
Desc: Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
Proteins in PDR annotated with:
   This term: 162 [Search]
   Term or descendants: 265 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008144 - drug binding (interactive image map)

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