| Protein: | cdk-4 |
| Organism: | Caenorhabditis elegans |
| Length: | 342 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cdk-4.
| Description | E-value | Query Range |
Subject Range |
|
|
286.0 | [0..13] | [338..237] |
|
Region A: Residues: [1-342] |
1 11 21 31 41 51
| | | | | |
1 MCENLYGEEY KMEILRLQKM MNNMTCGQMA KPLTMKDFQI HQALGKGAYG NVYRVRSLHD 60
61 GKDYALKQIM ISSKNEGIPQ SVLREITVMK HLARKAHPNI ISLKSVFHQL DPVRAILKIN 120
121 MIMERCDWDL HTFLRNIPRG VPEQQAKHVT AQIVRALDFL HTHSIIHRDL KPQNILLNRD 180
181 QTVKLADFGL SKEYSNTTAF TTLVVTLWYR SPEVLLQSYY NSTVDMWALG CIVSEIYCRQ 240
241 PLFVGQNEAE QLTDIFKKMG TPVGKDWPSE SVIARDSFPQ YRPTNLKDLS PQMSKQAIEF 300
301 VQQCLRYDHS KRLSARGALS HPFLKPAVAT KSRVLKQINF NK
|
| Detection Method: |  |
| Confidence: | 75.522879 |
| Match: | 1h1pA |
| Description: | Cyclin-dependent PK, CDK2 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| acetylcholine receptor activator activity | 5.9159846946654 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 5.68265749805481 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 4.62392503670521 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| calmodulin-dependent protein kinase activity | 4.31938467136214 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| structural molecule activity | 3.82327979736517 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 3.41480681854114 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 3.40140621607334 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 2.8153155526437 | bayes_pls_golite062009 |
| telethonin binding | 2.81155575828766 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 2.79505438761262 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| histone kinase activity (H3-S10 specific) | 2.61590507533614 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.59526003830791 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 2.52531786618214 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 2.46424348876434 | bayes_pls_golite062009 |
| signal transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| molecular transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| receptor activity | 2.39311927684508 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 2.37122853419919 | bayes_pls_golite062009 |
| protein binding | 2.276111749106 | bayes_pls_golite062009 |
| tubulin binding | 2.18641675163967 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.12615078788254 | bayes_pls_golite062009 |
| receptor signaling protein activity | 2.10379226653669 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| ubiquitin-protein ligase activity | 1.94085498993561 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| alpha-actinin binding | 1.92962505218614 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 1.9016235206634 | bayes_pls_golite062009 |
| microtubule binding | 1.88110801192607 | bayes_pls_golite062009 |
| actin binding | 1.87817875565699 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.81249386965144 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 1.74206248731815 | bayes_pls_golite062009 |
| fibroblast growth factor 1 binding | 1.66976264488423 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| insulin receptor substrate binding | 1.62657794525303 | bayes_pls_golite062009 |
| JUN kinase kinase kinase activity | 1.60259443694567 | bayes_pls_golite062009 |
| transcription regulator activity | 1.56748951434625 | bayes_pls_golite062009 |
| growth factor binding | 1.53863828216563 | bayes_pls_golite062009 |
| nucleic acid binding | 1.46547714006072 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 1.42275431028856 | bayes_pls_golite062009 |
| DNA binding | 1.35333135345112 | bayes_pls_golite062009 |
| ErbB-3 class receptor binding | 1.34841233233438 | bayes_pls_golite062009 |
| ErbB-2 class receptor binding | 1.33825339298024 | bayes_pls_golite062009 |
| kinase binding | 1.26086833316556 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 1.2266791546014 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| transcription elongation regulator activity | 1.16995153203536 | bayes_pls_golite062009 |
| transcription repressor activity | 1.14496167267281 | bayes_pls_golite062009 |
| transporter activity | 1.11833481501707 | bayes_pls_golite062009 |
| non-membrane spanning protein tyrosine kinase activity | 1.11664317075762 | bayes_pls_golite062009 |
| transcription factor activity | 1.10928254946881 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 1.10045286406485 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 1.10045286406485 | bayes_pls_golite062009 |
| protein kinase binding | 1.06030596516506 | bayes_pls_golite062009 |
| cation channel activity | 1.04999722123563 | bayes_pls_golite062009 |
| transcription activator activity | 0.997272622653026 | bayes_pls_golite062009 |
| PTB domain binding | 0.9900774724568 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.97575992765505 | bayes_pls_golite062009 |
| insulin-like growth factor receptor binding | 0.872782211382796 | bayes_pls_golite062009 |
| fibroblast growth factor binding | 0.870666814073948 | bayes_pls_golite062009 |
| MAP kinase activity | 0.81943579965027 | bayes_pls_golite062009 |
| actin filament binding | 0.794152600084 | bayes_pls_golite062009 |
| fibroblast growth factor receptor activity | 0.75189004129952 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.705905455086486 | bayes_pls_golite062009 |
| beta-catenin binding | 0.693246095477001 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.612883428421652 | bayes_pls_golite062009 |
| JUN kinase kinase kinase kinase activity | 0.546647574638943 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activating kinase activity | 0.529121666062889 | bayes_pls_golite062009 |
| activin binding | 0.510364757301021 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| enzyme binding | 0.46284745266176 | bayes_pls_golite062009 |
| protein kinase C activity | 0.41587987561486 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.401250804041384 | bayes_pls_golite062009 |
| structural constituent of muscle | 0.399773397398032 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| JUN kinase kinase activity | 0.332372116912461 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.318153468064373 | bayes_pls_golite062009 |
| channel activity | 0.287189255116606 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 0.287189255116606 | bayes_pls_golite062009 |
| insulin receptor binding | 0.266450215230107 | bayes_pls_golite062009 |
| substrate-specific channel activity | 0.261869836686301 | bayes_pls_golite062009 |
| RNA binding | 0.245748631571068 | bayes_pls_golite062009 |
| ion channel activity | 0.241519346930618 | bayes_pls_golite062009 |
| protein complex binding | 0.239339759110451 | bayes_pls_golite062009 |
| insulin receptor activity | 0.237134032032089 | bayes_pls_golite062009 |
| SH2 domain binding | 0.226760162354251 | bayes_pls_golite062009 |
| ligase activity, forming carbon-oxygen bonds | 0.149958560815481 | bayes_pls_golite062009 |
| ligase activity, forming aminoacyl-tRNA and related compounds | 0.149958560815481 | bayes_pls_golite062009 |
| aminoacyl-tRNA ligase activity | 0.14842991990838 | bayes_pls_golite062009 |
| peptide binding | 0.118578378753757 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity, type I | 0.0506751594607393 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.0040394359628233 | bayes_pls_golite062009 |
| brain-derived neurotrophic factor binding | 0.00315481858218991 | bayes_pls_golite062009 |
