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View Structure Prediction Details

Protein: SNQ2
Organism: Saccharomyces cerevisiae
Length: 1501 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SNQ2.

Description E-value Query
Range		 Subject
Range
gi|18152891 - gi|18152891|gb|AAK62810.2|AF227914_1 ATP-binding cassette transporter ABC1 [Venturia inaequalis]
 0.0 [17..1496] [61..1520]
CDR4_CANAX - ABC transporter CDR4 OS=Candida albicans GN=CDR4 PE=3 SV=1
 0.0 [12..1480] [4..1480]
gi|23304858, gi|... - gi|23304858|emb|CAC59691.2| ABC-transporter [Filobasidiella neoformans], gi|18478280|emb|CAD21006.1|...
 0.0 [4..1477] [38..1543]
gi|445052, gi|295839 - gi|445052|prf||1908372A SNQ2 gene, gi|295839|emb|CAA47270.1| 169 kDa protein [Saccharomyces cerevisi...
 0.0 [1..1490] [1..1490]
gi|66826585, gi|... - gi|66826585|ref|XP_646647.1| ABC transporter G family protein [Dictyostelium discoideum AX4], gi|604...
ABCGJ_DICDI - ABC transporter G family member 19 OS=Dictyostelium discoideum GN=abcG19 PE=3 SV=1
 0.0 [36..1481] [5..1449]
gi|6175524 - gi|6175524|gb|AAF05069.1|AF109723_1 ATP-binding cassette transporter [Candida glabrata]
 0.0 [1..1484] [1..1495]
gi|14278974 - gi|14278974|dbj|BAB59028.1| ABC transporter PMR5 [Penicillium digitatum]
 0.0 [64..1483] [4..1413]

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Predicted Domain #1
Region A:
Residues: [1-150] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNIKSTQDS SHNAVARSSS ASFAASEESF TGITHDKDEQ SDTPADKLTK MLTGPARDTA  60
   61 SQISATVSEM APDVVSKVES FADALSRHTT RSGAFNMDSD SDDGFDAHAI FESFVRDADE 120
  121 QGIHIRKAGV TIEDVSAKGV DASALEGATF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [151-432] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNILCLPLTI FKGIKAKRHQ KMRQIISNVN ALAEAGEMIL VLGRPGAGCS SFLKVTAGEI  60
   61 DQFAGGVSGE VAYDGIPQEE MMKRYKADVI YNGELDVHFP YLTVKQTLDF AIACKTPALR 120
  121 VNNVSKKEYI ASRRDLYATI FGLRHTYNTK VGNDFVRGVS GGERKRVSIA EALAAKGSIY 180
  181 CWDNATRGLD ASTALEYAKA IRIMTNLLKS TAFVTIYQAS ENIYETFDKV TVLYSGKQIY 240
  241 FGLIHEAKPY FAKMGYLCPP RQATAEFLTA LTDPNGFHLI KP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 125.9897
Match: 1l2tA_
Description: MJ0796
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [433-498] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GYENKVPRTA EEFETYWLNS PEFAQMKKDI AAYKEKVNTE KTKEVYDESM AQEKSKYTRK  60
   61 KSYYTV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [499-633] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SYWEQVKLCT QRGFQRIYGN KSYTVINVCS AIIQSFITGS LFYNTPSSTS GAFSRGGVLY  60
   61 FALLYYSLMG LANISFEHRP ILQKHKGYSL YHPSAEAIGS TLASFPFRMI GLTCFFIILF 120
  121 FLSGLHRTAG SFFTI

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [652-831] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSVCDTLSQA NSISGILMMS ISMYSTYMIQ LPSMHPWFKW ISYVLPIRYA FESMLNAEFH  60
   61 GRHMDCANTL VPSGGDYDNL SDDYKVCAFV GSKPGQSYVL GDDYLKNQFQ YVYKHTWRNF 120
  121 GILWCFLLGY VVLKVIFTEY KRPVKGGGDA LIFKKGSKRF IAHADEESPD NVNDIDAKEQ 180
  181

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 169.9897
Match: 1jsqA_
Description: MsbA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
lipid transporter activity 7.47642599298853 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 5.57844095962502 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 5.57813579764186 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 5.57813579764186 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 5.5689620139321 bayes_pls_golite062009
primary active transmembrane transporter activity 5.55992639965745 bayes_pls_golite062009
active transmembrane transporter activity 5.50005167063544 bayes_pls_golite062009
ATPase activity, coupled 4.98276715440477 bayes_pls_golite062009
ATPase activity 4.69795387297193 bayes_pls_golite062009
nucleoside-triphosphatase activity 4.45923622153365 bayes_pls_golite062009
sterol transporter activity 4.45355165759136 bayes_pls_golite062009
pyrophosphatase activity 4.39781350157199 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 4.38133275795019 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4.38085303582726 bayes_pls_golite062009
transporter activity 3.71239480053329 bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism 3.57926427233638 bayes_pls_golite062009
ion transmembrane transporter activity 3.35436118751376 bayes_pls_golite062009
hydrolase activity 3.14498892233323 bayes_pls_golite062009
transmembrane transporter activity 3.13960906549884 bayes_pls_golite062009
substrate-specific transporter activity 3.1318898376276 bayes_pls_golite062009
cation transmembrane transporter activity 3.08390071341252 bayes_pls_golite062009
iron ion transmembrane transporter activity 3.05511942104215 bayes_pls_golite062009
ATP binding 3.01346604299372 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.00745742755195 bayes_pls_golite062009
drug transmembrane transporter activity 2.97119034312001 bayes_pls_golite062009
adenyl ribonucleotide binding 2.96271391116269 bayes_pls_golite062009
adenyl nucleotide binding 2.91131545957759 bayes_pls_golite062009
metal ion transmembrane transporter activity 2.88476360771975 bayes_pls_golite062009
cholesterol transporter activity 2.72457626066894 bayes_pls_golite062009
purine ribonucleotide binding 2.70262534541085 bayes_pls_golite062009
ribonucleotide binding 2.70178191749524 bayes_pls_golite062009
organic acid transmembrane transporter activity 2.67957846350199 bayes_pls_golite062009
carboxylic acid transmembrane transporter activity 2.67815672695824 bayes_pls_golite062009
purine nucleotide binding 2.6583477492092 bayes_pls_golite062009
nucleotide binding 2.62374702628143 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 2.61311581579476 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 2.40292717311506 bayes_pls_golite062009
amine transmembrane transporter activity 2.29486577878686 bayes_pls_golite062009
amine-transporting ATPase activity 2.26176677225712 bayes_pls_golite062009
2.20174656498665 bayes_pls_golite062009
syntaxin-13 binding 2.15656963765495 bayes_pls_golite062009
apolipoprotein A-I binding 2.15656963765495 bayes_pls_golite062009
apolipoprotein receptor activity 2.15656963765495 bayes_pls_golite062009
apolipoprotein A-I receptor activity 2.15656963765495 bayes_pls_golite062009
proton-transporting ATPase activity, rotational mechanism 1.95782378818812 bayes_pls_golite062009
binding 1.84115074893083 bayes_pls_golite062009
transition metal ion transmembrane transporter activity 1.82177108193332 bayes_pls_golite062009
fluconazole transporter activity 1.75428613304237 bayes_pls_golite062009
azole transporter activity 1.75428613304237 bayes_pls_golite062009
nucleic acid binding 1.62884148289979 bayes_pls_golite062009
amino acid transmembrane transporter activity 1.59627719545436 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 1.58971273330352 bayes_pls_golite062009
DNA binding 1.53176391519962 bayes_pls_golite062009
transcription regulator activity 1.49517431175162 bayes_pls_golite062009
anion transmembrane-transporting ATPase activity 1.41230790551643 bayes_pls_golite062009
peptide-transporting ATPase activity 1.37783759788533 bayes_pls_golite062009
cation channel activity 1.33585529285301 bayes_pls_golite062009
signal recognition particle binding 1.23869719200594 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions 1.23799860254751 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
peptide transporter activity 1.19353064661766 bayes_pls_golite062009
potassium channel activity 1.17288958041707 bayes_pls_golite062009
GTPase activity 1.16964908174651 bayes_pls_golite062009
voltage-gated cation channel activity 1.00384984515681 bayes_pls_golite062009
voltage-gated ion channel activity 0.889208591820696 bayes_pls_golite062009
voltage-gated channel activity 0.871525745291603 bayes_pls_golite062009
0.869999622006359 bayes_pls_golite062009
ion channel activity 0.848261056209476 bayes_pls_golite062009
channel activity 0.806331380134838 bayes_pls_golite062009
passive transmembrane transporter activity 0.806331380134838 bayes_pls_golite062009
substrate-specific channel activity 0.799997700906738 bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity 0.767424210804186 bayes_pls_golite062009
phospholipid transporter activity 0.755445322666929 bayes_pls_golite062009
motor activity 0.677658554107 bayes_pls_golite062009
gated channel activity 0.650050847753837 bayes_pls_golite062009
DNA-dependent ATPase activity 0.62832939629645 bayes_pls_golite062009
branched-chain aliphatic amino acid transmembrane transporter activity 0.442220326523999 bayes_pls_golite062009
anion transmembrane transporter activity 0.43332053110728 bayes_pls_golite062009
catalytic activity 0.368034275052766 bayes_pls_golite062009
transcription factor activity 0.344643343870781 bayes_pls_golite062009
canalicular bile acid transmembrane transporter activity 0.301752323171649 bayes_pls_golite062009
signal transducer activity 0.286367085584159 bayes_pls_golite062009
molecular transducer activity 0.286367085584159 bayes_pls_golite062009
G-protein coupled receptor activity 0.169034229773346 bayes_pls_golite062009
amino acid-transporting ATPase activity 0.147644650870465 bayes_pls_golite062009
microtubule motor activity 0.11674780318211 bayes_pls_golite062009
protein transporter activity 0.104820191623932 bayes_pls_golite062009
cation-transporting ATPase activity 0.0536898657672154 bayes_pls_golite062009
structure-specific DNA binding 0.050232896280066 bayes_pls_golite062009
transcription activator activity 0.0291047953833683 bayes_pls_golite062009
ribonucleoprotein binding 0.0181245554613096 bayes_pls_golite062009
inorganic anion transmembrane transporter activity 0.0122470146764899 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [634-651] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YLFLTMCSEA INGLFEMV

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [832-1101] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FSSESSGAND EVFDDLEAKG VFIWKDVCFT IPYEGGKRML LDNVSGYCIP GTMTALMGES  60
   61 GAGKTTLLNT LAQRNVGIIT GDMLVNGRPI DASFERRTGY VQQQDIHIAE LTVRESLQFS 120
  121 ARMRRPQHLP DSEKMDYVEK IIRVLGMEEY AEALVGEVGC GLNVEQRKKL SIGVELVAKP 180
  181 DLLLFLDEPT SGLDSQSSWA IIQLLRKLSK AGQSILCTIH QPSATLFEEF DRLLLLRKGG 240
  241 QTVYFGDIGK NSATILNYFE RNGARKCDSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 169.9897
Match: 1jsqA_
Description: MsbA
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [1102-1392] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENPAEYILEA IGAGATASVK EDWHEKWLNS VEFEQTKEKV QDLINDLSKQ ETKSEVGDKP  60
   61 SKYATSYAYQ FRYVLIRTST SFWRSLNYIM SKMMLMLVGG LYIGFTFFNV GKSYVGLQNA 120
  121 MFAAFISIIL SAPAMNQIQG RAIASRELFE VRESQSNMFH WSLVLITQYL SELPYHLFFS 180
  181 TIFFVSSYFP LRIFFEASRS AVYFLNYCIM FQLYYVGLGL MILYMSPNLP SANVILGLCL 240
  241 SFMLSFCGVT QPVSLMPGFW TFMWKASPYT YFVQNLVGIM LHKKPVVCKK K

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1393-1501] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELNYFNPPNG STCGEYMKPF LEKATGYIEN PDATSDCAYC IYEVGDNYLT HISSKYSYLW  60
   61 RNFGIFWIYI FFNIIAMVCV YYLFHVRQSS FLSPVSILNK IKNIRKKKQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle