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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Rfc2. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 7 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

DNA replication factor C complex 1.3864E-7 7 11 3 6292
replication fork 9.504E-6 7 42 3 6292
chromosomal part 1.6505E-3 7 237 3 6292
chromosome 2.509E-3 7 274 3 6292
mitochondrial proton-transporting ATP synthase, central stalk 3.3344E-3 7 3 1 6292
proton-transporting ATP synthase, central stalk 3.3344E-3 7 3 1 6292
proton-transporting ATP synthase complex, catalytic core F(1) 5.552E-3 7 5 1 6292
mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) 5.552E-3 7 5 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

leading strand elongation 3.8158E-7 7 15 3 6292
mismatch repair 2.439E-6 7 27 3 6292
DNA strand elongation 3.7409E-6 7 31 3 6292
DNA strand elongation involved in DNA replication 3.7409E-6 7 31 3 6292
sister chromatid cohesion 4.126E-6 7 32 3 6292
DNA-dependent DNA replication 7.1923E-5 7 82 3 6292
DNA replication 2.4096E-4 7 123 3 6292
chromosome segregation 2.7117E-4 7 128 3 6292
DNA repair 8.9429E-4 7 192 3 6292
response to stress 1.11E-3 7 497 4 6292
regulation of hormone levels 1.1125E-3 7 1 1 6292
hormone metabolic process 1.1125E-3 7 1 1 6292
hormone biosynthetic process 1.1125E-3 7 1 1 6292
spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) 1.1125E-3 7 1 1 6292
auxin biosynthetic process 1.1125E-3 7 1 1 6292
auxin metabolic process 1.1125E-3 7 1 1 6292
cellular component organization 1.3786E-3 7 1582 6 6292
response to DNA damage stimulus 1.6304E-3 7 236 3 6292
organelle organization 2.7877E-3 7 1127 5 6292
cellular response to stress 2.9533E-3 7 290 3 6292
membrane invagination 4.4166E-3 7 94 2 6292
response to stimulus 5.631E-3 7 766 4 6292
cellular response to stimulus 6.3249E-3 7 379 3 6292
microautophagy 6.6592E-3 7 6 1 6292
spliceosomal conformational changes to generate catalytic conformation 9.9746E-3 7 9 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

DNA clamp loader activity 2.9465E-8 7 7 3 6292
protein-DNA loading ATPase activity 2.9465E-8 7 7 3 6292
ATPase activity, coupled 1.0005E-5 7 149 4 6292
DNA-dependent ATPase activity 2.1584E-5 7 55 3 6292
ATPase activity 3.9747E-5 7 211 4 6292
nucleoside-triphosphatase activity 2.2659E-4 7 329 4 6292
hydrolase activity, acting on acid anhydrides 2.9782E-4 7 353 4 6292
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.9782E-4 7 353 4 6292
pyrophosphatase activity 2.9782E-4 7 353 4 6292
purine nucleotide binding 1.3701E-3 7 52 2 6292
nucleotide binding 1.7614E-3 7 59 2 6292
DNA binding 2.0628E-3 7 256 3 6292
Rho guanyl-nucleotide exchange factor activity 4.4437E-3 7 4 1 6292

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