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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 4 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
FMP48
  • mitochondrion
    		•
  • biological_process
    		•
  • kinase activity
    		•
    MUC1
  • plasma membrane
    		•
  • cell-cell adhesion
  • filamentous growth
  • pseudohyphal growth
  • invasive growth in response to glucose limitation
  • biofilm formation
    		•
  • molecular_function
    		•
    YKU70
  • nuclear envelope
  • nuclear chromatin
  • nuclear telomeric heterochromatin
    		•
  • double-strand break repair via break-induced replication
  • double-strand break repair via homologous recombination
  • telomere maintenance
  • chromatin assembly or disassembly
  • chromatin silencing
  • double-strand break repair via nonhomologous end joining
    		•
  • RNA binding
  • damaged DNA binding
    		•
    YKU80
  • nuclear chromatin
  • nuclear telomeric heterochromatin
    		•
  • double-strand break repair via homologous recombination
  • telomere maintenance
  • chromatin assembly or disassembly
  • chromatin silencing
  • double-strand break repair via nonhomologous end joining
  • donor selection
    		•
  • DNA binding
  • RNA binding
  • damaged DNA binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    nuclear telomeric heterochromatin 6.3596E-6 4 7 2 6292
    telomeric heterochromatin 6.3596E-6 4 7 2 6292
    nuclear heterochromatin 6.3596E-6 4 7 2 6292
    heterochromatin 6.3596E-6 4 7 2 6292
    nuclear chromosome, telomeric region 7.6359E-5 4 23 2 6292
    chromosome, telomeric region 1.0585E-4 4 27 2 6292
    nuclear chromatin 7.8477E-4 4 73 2 6292
    chromatin 8.7301E-4 4 77 2 6292
    nuclear chromosome part 5.2287E-3 4 190 2 6292
    nuclear chromosome 7.4744E-3 4 228 2 6292
    chromosomal part 8.0617E-3 4 237 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    double-strand break repair via homologous recombination 6.9734E-5 4 22 2 6292
    double-strand break repair via nonhomologous end joining 9.0505E-5 4 25 2 6292
    recombinational repair 9.8027E-5 4 26 2 6292
    non-recombinational repair 1.6892E-4 4 34 2 6292
    chromatin assembly or disassembly 1.7912E-4 4 35 2 6292
    double-strand break repair 4.7822E-4 4 57 2 6292
    negative regulation of gene expression, epigenetic 1.4697E-3 4 100 2 6292
    gene silencing 1.4697E-3 4 100 2 6292
    regulation of gene expression, epigenetic 1.4697E-3 4 100 2 6292
    chromatin silencing 1.4697E-3 4 100 2 6292
    DNA recombination 1.9066E-3 4 114 2 6292
    regulation of biological quality 2.4982E-3 4 551 3 6292
    donor selection 2.5411E-3 4 4 1 6292
    cell-cell adhesion 3.1756E-3 4 5 1 6292
    negative regulation of transcription, DNA-dependent 3.5916E-3 4 157 2 6292
    negative regulation of RNA metabolic process 3.6369E-3 4 158 2 6292
    biofilm formation 3.8098E-3 4 6 1 6292
    negative regulation of transcription 3.9142E-3 4 164 2 6292
    negative regulation of gene expression 3.9142E-3 4 164 2 6292
    negative regulation of macromolecule biosynthetic process 4.4481E-3 4 175 2 6292
    negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 4.7016E-3 4 180 2 6292
    negative regulation of nitrogen compound metabolic process 4.7016E-3 4 180 2 6292
    biological adhesion 5.0773E-3 4 8 1 6292
    cell adhesion 5.0773E-3 4 8 1 6292
    negative regulation of biosynthetic process 5.1748E-3 4 189 2 6292
    negative regulation of cellular biosynthetic process 5.1748E-3 4 189 2 6292
    DNA repair 5.3374E-3 4 192 2 6292
    negative regulation of macromolecule metabolic process 5.3374E-3 4 192 2 6292
    double-strand break repair via break-induced replication 5.7106E-3 4 9 1 6292
    chromatin organization 5.954E-3 4 203 2 6292
    negative regulation of cellular metabolic process 6.3039E-3 4 209 2 6292
    negative regulation of metabolic process 6.3631E-3 4 210 2 6292
    response to DNA damage stimulus 7.9954E-3 4 236 2 6292
    negative regulation of cellular process 8.9471E-3 4 250 2 6292
    negative regulation of biological process 9.1576E-3 4 253 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    damaged DNA binding 1.6642E-5 4 11 2 6292
    DNA binding 9.3704E-3 4 256 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle