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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 4 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

CCR4-NOT complex 1.5343E-11 4 14 4 6292
CCR4-NOT core complex 5.3949E-9 4 8 3 6292
transcription factor complex 1.4893E-8 4 71 4 6292
nucleoplasm part 2.2451E-6 4 245 4 6292
nucleoplasm 3.0322E-6 4 264 4 6292
nuclear lumen 2.6539E-5 4 453 4 6292
organelle lumen 1.2008E-4 4 660 4 6292
intracellular organelle lumen 1.2008E-4 4 660 4 6292
membrane-enclosed lumen 1.5203E-4 4 700 4 6292
nuclear part 9.4015E-4 4 1103 4 6292
protein complex 1.0617E-3 4 1137 4 6292
macromolecular complex 4.5471E-3 4 1635 4 6292
Cdc73/Paf1 complex 5.0773E-3 4 8 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

nuclear-transcribed mRNA poly(A) tail shortening 5.3949E-9 4 8 3 6292
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 2.8115E-7 4 27 3 6292
mRNA 3'-end processing 4.3185E-7 4 31 3 6292
nuclear-transcribed mRNA catabolic process 8.0979E-7 4 38 3 6292
RNA elongation from RNA polymerase II promoter 8.7717E-7 4 39 3 6292
RNA 3'-end processing 1.1015E-6 4 42 3 6292
RNA elongation 1.361E-6 4 45 3 6292
regulation of transcription from RNA polymerase II promoter 1.6808E-6 4 228 4 6292
mRNA catabolic process 5.0107E-6 4 69 3 6292
RNA catabolic process 7.847E-6 4 80 3 6292
transcription from RNA polymerase II promoter 7.9001E-6 4 335 4 6292
regulation of transcription, DNA-dependent 1.0315E-5 4 358 4 6292
regulation of RNA metabolic process 1.0906E-5 4 363 4 6292
regulation of transcription 1.367E-5 4 384 4 6292
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.867E-5 4 415 4 6292
regulation of nitrogen compound metabolic process 1.8852E-5 4 416 4 6292
regulation of gene expression 2.4707E-5 4 445 4 6292
regulation of macromolecule biosynthetic process 2.7251E-5 4 456 4 6292
regulation of cellular biosynthetic process 3.1296E-5 4 472 4 6292
regulation of biosynthetic process 3.1563E-5 4 473 4 6292
regulation of macromolecule metabolic process 3.5776E-5 4 488 4 6292
transcription, DNA-dependent 4.0396E-5 4 503 4 6292
RNA biosynthetic process 4.2031E-5 4 508 4 6292
regulation of primary metabolic process 4.4059E-5 4 514 4 6292
regulation of cellular metabolic process 5.2125E-5 4 536 4 6292
regulation of metabolic process 5.655E-5 4 547 4 6292
transcription 5.8652E-5 4 552 4 6292
mRNA processing 5.8733E-5 4 156 3 6292
mRNA metabolic process 1.4924E-4 4 213 3 6292
regulation of cellular process 2.5447E-4 4 796 4 6292
cellular macromolecule catabolic process 2.8637E-4 4 265 3 6292
regulation of biological process 2.9228E-4 4 824 4 6292
macromolecule catabolic process 3.9009E-4 4 294 3 6292
RNA metabolic process 5.2568E-4 4 954 4 6292
RNA processing 8.3529E-4 4 380 3 6292
cellular catabolic process 1.084E-3 4 415 3 6292
cellular macromolecule biosynthetic process 1.2614E-3 4 1187 4 6292
macromolecule biosynthetic process 1.27E-3 4 1189 4 6292
biological regulation 1.3758E-3 4 1213 4 6292
gene expression 1.7224E-3 4 1283 4 6292
catabolic process 1.834E-3 4 496 3 6292
nucleic acid metabolic process 2.5494E-3 4 1415 4 6292
traversing start control point of mitotic cell cycle 3.8098E-3 4 6 1 6292
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.8261E-3 4 1566 4 6292
cellular biosynthetic process 3.8359E-3 4 1567 4 6292
biosynthetic process 4.1907E-3 4 1602 4 6292
cellular nitrogen compound metabolic process 6.2471E-3 4 1770 4 6292
nitrogen compound metabolic process 6.5492E-3 4 1791 4 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

3'-5'-exoribonuclease activity 1.7031E-7 4 23 3 6292
exoribonuclease activity 2.4994E-7 4 26 3 6292
exoribonuclease activity, producing 5'-phosphomonoesters 2.4994E-7 4 26 3 6292
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 5.7469E-7 4 34 3 6292
3'-5' exonuclease activity 6.2849E-7 4 35 3 6292
exonuclease activity 1.4558E-6 4 46 3 6292
ribonuclease activity 5.1173E-5 4 149 3 6292
nuclease activity 1.2179E-4 4 199 3 6292
hydrolase activity, acting on ester bonds 6.0599E-4 4 341 3 6292

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