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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 12 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ASK10
  • cytoplasm
  • DNA-directed RNA polymerase II, holoenzyme
  • response to oxidative stress
  • transcription
  • transcription regulator activity
  • ATG1
  • pre-autophagosomal structure
  • cytosol
  • vesicle organization
  • autophagy
  • protein serine/threonine kinase activity
  • BMH2
  • nucleus
  • ascospore formation
  • DNA damage checkpoint
  • glycogen metabolic process
  • pseudohyphal growth
  • Ras protein signal transduction
  • signal transduction during filamentous growth
  • negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
  • DNA binding
  • protein binding
  • KIC1
  • incipient cellular bud site
  • cellular bud
  • cytoplasm
  • mating projection tip
  • cell morphogenesis during vegetative growth
  • cell morphogenesis
  • cellular cell wall organization
  • kinase activity
  • NTH1
  • cytoplasm
  • cytosol
  • trehalose catabolic process
  • response to stress
  • alpha,alpha-trehalase activity
  • PIK1
  • nucleus
  • Golgi apparatus
  • ascospore formation
  • cytokinesis
  • phosphoinositide phosphorylation
  • post-Golgi vesicle-mediated transport
  • inositol lipid-mediated signaling
  • 1-phosphatidylinositol 4-kinase activity
  • REG1
  • protein phosphatase type 1 complex
  • cytoplasm
  • negative regulation of transcription from RNA polymerase II promoter
  • regulation of carbohydrate metabolic process
  • glycogen metabolic process
  • vacuolar protein catabolic process
  • protein phosphatase type 1 regulator activity
  • RFX1
  • nucleus
  • cytoplasm
  • negative regulation of transcription from RNA polymerase II promoter
  • DNA damage checkpoint
  • specific transcriptional repressor activity
  • SOG2
  • incipient cellular bud site
  • cellular bud
  • cytoplasm
  • mating projection tip
  • cell morphogenesis during vegetative growth
  • signal transduction
  • cytokinetic cell separation
  • molecular_function
  • UBP11
  • cellular_component
  • biological_process
  • ubiquitin-specific protease activity
  • YDR348C
  • cellular bud neck
  • biological_process
  • molecular_function
  • YNR014W
  • cytoplasm
  • biological_process
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    mating projection tip 1.916E-3 12 35 2 6292
    cell projection part 2.752E-3 12 42 2 6292
    incipient cellular bud site 3.1543E-3 12 45 2 6292
    cellular bud 3.3293E-3 12 166 3 6292
    site of polarized growth 3.4443E-3 12 168 3 6292
    cell projection 3.7311E-3 12 49 2 6292
    mating projection 3.7311E-3 12 49 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cell morphogenesis during vegetative growth 1.1916E-4 12 9 2 6292
    DNA damage checkpoint 2.9963E-4 12 14 2 6292
    DNA damage response, signal transduction 2.9963E-4 12 14 2 6292
    signal transduction 5.1943E-4 12 214 4 6292
    signal transmission 5.4769E-4 12 217 4 6292
    signaling process 5.4769E-4 12 217 4 6292
    DNA integrity checkpoint 6.2163E-4 12 20 2 6292
    signaling 9.6423E-4 12 252 4 6292
    anatomical structure morphogenesis 1.0381E-3 12 257 4 6292
    anatomical structure development 1.0844E-3 12 260 4 6292
    cellular developmental process 1.356E-3 12 276 4 6292
    glycogen metabolic process 1.6023E-3 12 32 2 6292
    energy reserve metabolic process 1.6023E-3 12 32 2 6292
    intracellular signaling pathway 2.2194E-3 12 144 3 6292
    developmental process 2.6579E-3 12 331 4 6292
    cellular glucan metabolic process 2.8832E-3 12 43 2 6292
    glucan metabolic process 2.8832E-3 12 43 2 6292
    signaling pathway 4.4543E-3 12 184 3 6292
    cellular polysaccharide metabolic process 4.6816E-3 12 55 2 6292
    negative regulation of macromolecule metabolic process 5.0207E-3 12 192 3 6292
    cell cycle checkpoint 5.1947E-3 12 58 2 6292
    polysaccharide metabolic process 5.5506E-3 12 60 2 6292
    negative regulation of transcription from RNA polymerase II promoter 5.5506E-3 12 60 2 6292
    trehalose catabolic process 5.7116E-3 12 3 1 6292
    negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 5.7116E-3 12 3 1 6292
    negative regulation of protein ubiquitination 5.7116E-3 12 3 1 6292
    negative regulation of ubiquitin-protein ligase activity 5.7116E-3 12 3 1 6292
    negative regulation of ligase activity 5.7116E-3 12 3 1 6292
    negative regulation of cellular metabolic process 6.3656E-3 12 209 3 6292
    negative regulation of metabolic process 6.4509E-3 12 210 3 6292
    glycoside catabolic process 7.6087E-3 12 4 1 6292
    negative regulation of protein modification process 7.6087E-3 12 4 1 6292
    phosphoinositide phosphorylation 9.5026E-3 12 5 1 6292
    regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 9.5026E-3 12 5 1 6292
    lipid phosphorylation 9.5026E-3 12 5 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    trehalase activity 5.7116E-3 12 3 1 6292
    1-phosphatidylinositol 4-kinase activity 5.7116E-3 12 3 1 6292
    alpha,alpha-trehalase activity 5.7116E-3 12 3 1 6292
    kinase activity 7.5284E-3 12 222 3 6292

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