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The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6. Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that activates, maintains or increases the rate of ubiquitin ligase activity that contributes to the mitotic cell cycle. Any process that modulates the frequency, rate or extent of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine. Any process that modulates the frequency, rate or extent of the addition of ubiquitin moieties to a protein. Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin ligase activity that contributes to the mitotic cell cycle. Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent. A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. A cell cycle process that modulates the frequency, rate or extent of ubiquitin ligase activity that contributes to the mitotic cell cycle.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
Acc: GO:0051439
Aspect: Biological Process
Desc: A cell cycle process that modulates the frequency, rate or extent of ubiquitin ligase activity that contributes to the mitotic cell cycle.
Synonyms:
  • regulation of ubiquitin-protein ligase activity during mitotic cell cycle
  • mitotic ubiquitin-protein ligase regulator
  • regulation of ubiquitin ligase activity during mitotic cell cycle
  • mitotic ubiquitin ligase regulator
  • mitotic anaphase-promoting complex regulator
  • mitotic SCF complex regulator
  • mitotic APC regulator
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 97 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0051439 - regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle