YRC Public Data Repository - Protein Complex GO Analysis

Complex Overview

From Publication:	Mewes, H. W. et al. MIPS: Analysis and annotation of proteins from whole genomes. Nucleic Acids Res. 32, D41-D44
Notes:	MIPS hand-curated complex set. MIPS complex ID: 440.40
Complex Size:	13 proteins

Complex Member Proteins

Protein	GO Cellular Component	GO Biological Process	GO Molecular Function
BI4	mitochondrion	Group I intron splicing	RNA binding
CBP6	mitochondrion	translation	molecular_function
MRS1	mitochondrion	Group I intron splicing	RNA binding endodeoxyribonuclease activity
MRS2	mitochondrion mitochondrial inner membrane	Group II intron splicing mitochondrial magnesium ion transport	magnesium ion transmembrane transporter activity
MRS3	mitochondrion	RNA splicing mitochondrial transport mitochondrial iron ion transport	iron ion transmembrane transporter activity surfactant activity
MRS4	mitochondrion	RNA splicing mitochondrial transport mitochondrial iron ion transport	iron ion transmembrane transporter activity surfactant activity
MSS1	mitochondrion mitochondrial inner membrane	tRNA modification translation	GTP binding
MSS116	mitochondrial matrix mitochondrion	RNA splicing	RNA binding RNA-dependent ATPase activity ATP-dependent RNA helicase activity
MSS18	mitochondrion	Group I intron splicing	molecular_function
MTF2	mitochondrion	mRNA processing translation	RNA binding
NAM2	mitochondrion	leucyl-tRNA aminoacylation Group I intron splicing	leucine-tRNA ligase activity mRNA binding
PET54	mitochondrial matrix mitochondrion mitochondrial inner membrane	Group I intron splicing translation	translation regulator activity RNA binding
TIM10	mitochondrial intermembrane space mitochondrion mitochondrial intermembrane space protein transporter complex	protein import into mitochondrial inner membrane	protein transporter activity unfolded protein binding

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
mitochondrion	1.8026E-10	13	1125	13	6292
cytoplasmic part	5.494E-6	13	2482	13	6292
cytoplasm	5.8578E-4	13	3552	13	6292
membrane-bounded organelle	1.2767E-3	13	3771	13	6292
intracellular membrane-bounded organelle	1.2767E-3	13	3771	13	6292
mitochondrial part	1.8561E-3	13	475	5	6292
mitochondrial envelope	2.9688E-3	13	312	4	6292
intracellular organelle	3.4477E-3	13	4070	13	6292
organelle	3.4587E-3	13	4071	13	6292
mitochondrial inner membrane	4.8459E-3	13	174	3	6292
organelle inner membrane	5.7537E-3	13	185	3	6292
mitochondrial intermembrane space protein transporter complex	8.2408E-3	13	4	1	6292

Biological Process Analysis

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
RNA splicing, via transesterification reactions with guanosine as nucleophile	3.287E-13	13	7	5	6292
Group I intron splicing	3.287E-13	13	7	5	6292
RNA splicing	3.9894E-13	13	132	9	6292
RNA processing	2.3731E-12	13	380	11	6292
RNA splicing, via transesterification reactions	3.2736E-8	13	107	6	6292
gene expression	5.2425E-8	13	1283	12	6292
RNA metabolic process	5.3775E-8	13	954	11	6292
nucleic acid metabolic process	3.5616E-6	13	1415	11	6292
mitochondrial iron ion transport	3.9411E-6	13	2	2	6292
mitochondrial transport	7.3555E-6	13	66	4	6292
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	1.0311E-5	13	1566	11	6292
di-, tri-valent inorganic cation transport	3.3022E-5	13	32	3	6292
cellular nitrogen compound metabolic process	3.6818E-5	13	1770	11	6292
nitrogen compound metabolic process	4.1589E-5	13	1791	11	6292
cellular macromolecule metabolic process	4.4721E-5	13	2285	12	6292
macromolecule metabolic process	6.1467E-5	13	2349	12	6292
metal ion transport	1.9914E-4	13	58	3	6292
iron ion transport	5.9184E-4	13	18	2	6292
translation	6.4023E-4	13	376	5	6292
primary metabolic process	6.6865E-4	13	2896	12	6292
cation transport	8.546E-4	13	95	3	6292
cellular metabolic process	1.1248E-3	13	3033	12	6292
ion transport	1.6828E-3	13	120	3	6292
metabolic process	1.7612E-3	13	3157	12	6292
Group II intron splicing	2.0661E-3	13	1	1	6292
transition metal ion transport	3.3927E-3	13	43	2	6292
mitochondrial magnesium ion transport	4.1283E-3	13	2	1	6292
leucyl-tRNA aminoacylation	4.1283E-3	13	2	1	6292

Molecular Function Analysis

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
surfactant activity	2.3591E-5	13	4	2	6292
di-, tri-valent inorganic cation transmembrane transporter activity	4.3418E-5	13	35	3	6292
RNA binding	4.5706E-5	13	367	6	6292
metal ion transmembrane transporter activity	9.9386E-5	13	46	3	6292
iron ion transmembrane transporter activity	2.571E-4	13	12	2	6292
inorganic cation transmembrane transporter activity	1.0216E-3	13	101	3	6292
nucleic acid binding	1.2273E-3	13	666	6	6292
transition metal ion transmembrane transporter activity	1.4452E-3	13	28	2	6292
binding	1.4925E-3	13	1294	8	6292
cation transmembrane transporter activity	1.6032E-3	13	118	3	6292
ion transmembrane transporter activity	2.9508E-3	13	146	3	6292
substrate-specific transporter activity	3.8874E-3	13	336	4	6292
leucine-tRNA ligase activity	4.1283E-3	13	2	1	6292
magnesium ion transmembrane transporter activity	6.1865E-3	13	3	1	6292
transporter activity	7.5211E-3	13	404	4	6292
obsolete_molecular_function	8.5513E-3	13	69	2	6292

View Protein Complex Details

Complex Overview

Complex Member Proteins

Cellular Component Analysis

Biological Process Analysis

Molecular Function Analysis