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The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. The splicing of Group I introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group I introns and involved in determining the locations of the splice sites (there do not appear to be consensus splice site sequences) as well as having a role in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions, generally with exogenous guanosine as the initiating nucleophile. The intron is excised as a linear piece (though it may subsequently circularize). Splicing of RNA via a series of two transesterification reactions. Splicing of RNA via a series of two transesterification reactions with exogenous guanosine as the initiating nucleophile.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: RNA splicing, via transesterification reactions with guanosine as nucleophile
Acc: GO:0000376
Aspect: Biological Process
Desc: Splicing of RNA via a series of two transesterification reactions with exogenous guanosine as the initiating nucleophile.
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 13 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0000376 - RNA splicing, via transesterification reactions with guanosine as nucleophile (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle