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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 5 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RAD52
  • nucleus
  • nuclear chromosome
  • meiotic DNA recombinase assembly
  • double-strand break repair via break-induced replication
  • double-strand break repair via single-strand annealing
  • telomere maintenance via recombination
  • double-strand break repair via synthesis-dependent strand annealing
  • DNA recombinase assembly
  • postreplication repair
  • DNA strand annealing activity
  • recombinase activity
  • RFA1
  • chromosome, telomeric region
  • nucleus
  • cytoplasm
  • DNA replication factor A complex
  • DNA strand elongation involved in DNA replication
  • double-strand break repair via homologous recombination
  • DNA recombination
  • nucleotide-excision repair
  • telomere maintenance via recombination
  • DNA unwinding involved in replication
  • postreplication repair
  • DNA replication, synthesis of RNA primer
  • damaged DNA binding
  • single-stranded DNA binding
  • RFA2
  • chromosome, telomeric region
  • DNA replication factor A complex
  • DNA strand elongation involved in DNA replication
  • double-strand break repair via homologous recombination
  • DNA recombination
  • nucleotide-excision repair
  • DNA unwinding involved in replication
  • postreplication repair
  • DNA replication, synthesis of RNA primer
  • DNA binding
  • RFA3
  • chromosome, telomeric region
  • DNA replication factor A complex
  • DNA strand elongation involved in DNA replication
  • double-strand break repair via homologous recombination
  • DNA recombination
  • nucleotide-excision repair
  • DNA unwinding involved in replication
  • postreplication repair
  • DNA replication, synthesis of RNA primer
  • DNA binding
  • RIM1
  • mitochondrion
  • mitochondrial nucleoid
  • mitochondrial genome maintenance
  • single-stranded DNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    DNA replication factor A complex 2.4099E-10 5 3 3 6292
    nuclear replisome 1.9594E-7 5 18 3 6292
    replisome 1.9594E-7 5 18 3 6292
    nuclear replication fork 2.7361E-7 5 20 3 6292
    chromosome, telomeric region 7.0086E-7 5 27 3 6292
    replication fork 2.7408E-6 5 42 3 6292
    protein-DNA complex 6.9607E-6 5 57 3 6292
    nuclear chromosome 8.1644E-6 5 228 4 6292
    chromosome 1.7002E-5 5 274 4 6292
    non-membrane-bounded organelle 8.1528E-5 5 959 5 6292
    intracellular non-membrane-bounded organelle 8.1528E-5 5 959 5 6292
    nuclear chromosome part 2.592E-4 5 190 3 6292
    chromosomal part 4.9889E-4 5 237 3 6292
    nuclear part 4.0435E-3 5 1103 4 6292
    organelle part 6.2578E-3 5 2282 5 6292
    intracellular organelle part 6.2578E-3 5 2282 5 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    postreplication repair 2.3409E-10 5 18 4 6292
    double-strand break repair via homologous recombination 5.5932E-10 5 22 4 6292
    recombinational repair 1.1425E-9 5 26 4 6292
    DNA replication, synthesis of RNA primer 2.4087E-9 5 5 3 6292
    double-strand break repair 3.0068E-8 5 57 4 6292
    DNA unwinding involved in replication 8.7489E-8 5 14 3 6292
    DNA geometric change 2.7361E-7 5 20 3 6292
    DNA duplex unwinding 2.7361E-7 5 20 3 6292
    DNA recombination 5.0423E-7 5 114 4 6292
    DNA strand elongation 1.076E-6 5 31 3 6292
    DNA strand elongation involved in DNA replication 1.076E-6 5 31 3 6292
    nucleotide-excision repair 2.016E-6 5 38 3 6292
    DNA repair 4.1045E-6 5 192 4 6292
    DNA conformation change 7.3387E-6 5 58 3 6292
    response to DNA damage stimulus 9.3706E-6 5 236 4 6292
    DNA-dependent DNA replication 2.0942E-5 5 82 3 6292
    cellular response to stress 2.1316E-5 5 290 4 6292
    telomere maintenance via recombination 6.0363E-5 5 16 2 6292
    cellular response to stimulus 6.1753E-5 5 379 4 6292
    DNA replication 7.0856E-5 5 123 3 6292
    response to stress 1.8041E-4 5 497 4 6292
    mitotic recombination 2.6416E-4 5 33 2 6292
    DNA metabolic process 3.428E-4 5 585 4 6292
    response to stimulus 9.8503E-4 5 766 4 6292
    RNA biosynthetic process 4.6241E-3 5 508 3 6292
    DNA recombinase assembly 4.7604E-3 5 6 1 6292
    meiotic DNA recombinase assembly 4.7604E-3 5 6 1 6292
    double-strand break repair via synthesis-dependent strand annealing 5.552E-3 5 7 1 6292
    double-strand break repair via break-induced replication 7.1338E-3 5 9 1 6292
    double-strand break repair via single-strand annealing 7.1338E-3 5 9 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    DNA binding 1.0737E-7 5 256 5 6292
    single-stranded DNA binding 1.3453E-7 5 16 3 6292
    structure-specific DNA binding 3.1605E-6 5 44 3 6292
    nucleic acid binding 1.3109E-5 5 666 5 6292
    binding 3.6564E-4 5 1294 5 6292
    DNA strand annealing activity 3.1756E-3 5 4 1 6292
    recombinase activity 3.1756E-3 5 4 1 6292
    damaged DNA binding 8.7135E-3 5 11 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle