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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 12 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

U1 snRNP 4.8142E-26 12 17 10 6292
small nuclear ribonucleoprotein complex 3.1217E-19 12 63 10 6292
commitment complex 9.882E-15 12 12 6 6292
U2-type spliceosomal complex 9.882E-15 12 12 6 6292
ribonucleoprotein complex 7.8427E-14 12 514 12 6292
spliceosomal complex 8.4783E-11 12 45 6 6292
nuclear part 8.0153E-10 12 1103 12 6292
macromolecular complex 9.1989E-8 12 1635 12 6292
nucleus 1.3278E-6 12 2041 12 6292
organelle part 5.0851E-6 12 2282 12 6292
intracellular organelle part 5.0851E-6 12 2282 12 6292
nuclear cap binding complex 9.9937E-6 12 3 2 6292
RNA cap binding complex 4.981E-5 12 6 2 6292
membrane-bounded organelle 2.1329E-3 12 3771 12 6292
intracellular membrane-bounded organelle 2.1329E-3 12 3771 12 6292
intracellular organelle 5.3355E-3 12 4070 12 6292
organelle 5.3513E-3 12 4071 12 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

nuclear mRNA splicing, via spliceosome 1.1622E-22 12 99 12 6292
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 1.3207E-22 12 100 12 6292
RNA splicing, via transesterification reactions 3.1165E-22 12 107 12 6292
RNA splicing 4.3877E-21 12 132 12 6292
mRNA processing 3.5331E-20 12 156 12 6292
mRNA metabolic process 1.6695E-18 12 213 12 6292
RNA processing 1.9966E-15 12 380 12 6292
RNA metabolic process 1.3916E-10 12 954 12 6292
gene expression 4.9591E-9 12 1283 12 6292
nucleic acid metabolic process 1.6138E-8 12 1415 12 6292
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 5.4733E-8 12 1566 12 6292
mRNA splice site selection 1.0569E-7 12 6 3 6292
cellular nitrogen compound metabolic process 2.3908E-7 12 1770 12 6292
nitrogen compound metabolic process 2.7555E-7 12 1791 12 6292
spliceosome assembly 4.257E-6 12 18 3 6292
cellular macromolecule metabolic process 5.1661E-6 12 2285 12 6292
macromolecule metabolic process 7.2022E-6 12 2349 12 6292
primary metabolic process 8.9282E-5 12 2896 12 6292
cellular metabolic process 1.5563E-4 12 3033 12 6292
metabolic process 2.5194E-4 12 3157 12 6292
ribonucleoprotein complex assembly 6.0496E-4 12 92 3 6292
nuclear mRNA 5'-splice site recognition 1.9072E-3 12 1 1 6292
cellular macromolecular complex assembly 4.3192E-3 12 182 3 6292
nuclear mRNA cis splicing, via spliceosome 5.7116E-3 12 3 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

RNA binding 1.3066E-15 12 367 12 6292
nucleic acid binding 1.8092E-12 12 666 12 6292
mRNA binding 1.7035E-11 12 35 6 6292
binding 5.4965E-9 12 1294 12 6292
pre-mRNA 5'-splice site binding 1.9072E-3 12 1 1 6292
U1 snRNA binding 1.9072E-3 12 1 1 6292
RNA cap binding 3.811E-3 12 2 1 6292
snRNA binding 9.5026E-3 12 5 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle