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Recognition of the intron 5'-splice site by components of the assembling spliceosome. The aggregation, arrangement and bonding together of the spliceosome, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. Recognition of both the 5' and 3'-splice sites and positioning them in the correct alignment with respect to each other so that the second catalytic step of nuclear mRNA splicing can occur. The joining together of exons from one or more primary transcripts of nuclear messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex. The joining together, after removal of an intervening sequence composed of one or more introns, of two segments of the same RNA molecule via spliceosomal catalysis to produce an mRNA composed only of exon sequences that all came from the same primary transcript. Selection of a splice site by components of the assembling spliceosome.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: nuclear mRNA 5'-splice site recognition
Acc: GO:0000395
Aspect: Biological Process
Desc: Recognition of the intron 5'-splice site by components of the assembling spliceosome.
Synonyms:
  • spliceosomal commitment complex biosynthesis
  • U2-type nuclear mRNA 5'-splice site recognition
  • GO:0000369
  • GO:0000368
  • U2-type nuclear mRNA 5' splice site recognition
  • spliceosomal commitment complex formation
  • spliceosomal E complex formation
  • U12-type nuclear mRNA 5' splice site recognition
  • nuclear mRNA 5' splice site recognition
  • spliceosomal CC complex formation
  • U12-type nuclear mRNA 5'-splice site recognition
  • spliceosomal E complex biosynthesis
  • spliceosomal CC complex biosynthesis
Proteins in PDR annotated with:
   This term: 16 [Search]
   Term or descendants: 16 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0000395 - nuclear mRNA 5'-splice site recognition (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle