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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 21 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
BMS1
  • nucleus
  • cytoplasm
  • mitochondrion
  • nuclear outer membrane
  • nucleolus
  • ribosome assembly
  • rRNA processing
  • GTP binding
  • ECM16
  • mitochondrion
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • RNA helicase activity
  • EMG1
  • nucleus
  • cytoplasm
  • nuclear microtubule
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • ENP1
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • preribosome, small subunit precursor
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • IMP3
  • small-subunit processome
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • KRE33
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • MPP10
  • nucleus
  • small-subunit processome
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • NAN1
  • RENT complex
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • NOC4
  • nucleus
  • Noc4p-Nop14p complex
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • NOP1
  • nuclear outer membrane
  • nucleolus
  • ribosome
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • RNA methylation
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • snoRNA 3'-end processing
  • methyltransferase activity
  • NOP14
  • mitochondrion
  • Noc4p-Nop14p complex
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • snoRNA binding
  • SOF1
  • nuclear outer membrane
  • nucleolus
  • small nuclear ribonucleoprotein complex
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • snoRNA binding
  • UTP10
  • mitochondrion
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP15
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP20
  • cytoplasm
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • rRNA processing
  • snoRNA binding
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • UTP30
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • UTP4
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP6
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP7
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • UTP8
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    small nucleolar ribonucleoprotein complex 7.5149E-31 21 72 17 6292
    nuclear outer membrane 4.2261E-20 21 86 13 6292
    nuclear membrane 2.2335E-19 21 97 13 6292
    ribonucleoprotein complex 2.0959E-17 21 514 18 6292
    nucleolus 1.4025E-16 21 211 14 6292
    outer membrane 8.0237E-16 21 178 13 6292
    organelle outer membrane 8.0237E-16 21 178 13 6292
    nuclear envelope 3.4991E-15 21 199 13 6292
    nuclear membrane-endoplasmic reticulum network 2.6178E-14 21 232 13 6292
    nuclear lumen 6.0385E-12 21 453 14 6292
    endomembrane system 2.7453E-11 21 398 13 6292
    envelope 5.5286E-10 21 505 13 6292
    organelle envelope 5.5286E-10 21 505 13 6292
    organelle lumen 9.8957E-10 21 660 14 6292
    intracellular organelle lumen 9.8957E-10 21 660 14 6292
    membrane-enclosed lumen 2.171E-9 21 700 14 6292
    nuclear part 6.0814E-9 21 1103 16 6292
    macromolecular complex 1.5644E-8 21 1635 18 6292
    membrane part 1.5823E-8 21 662 13 6292
    organelle membrane 2.7211E-8 21 692 13 6292
    preribosome 6.4886E-8 21 34 5 6292
    non-membrane-bounded organelle 1.3598E-7 21 959 14 6292
    intracellular non-membrane-bounded organelle 1.3598E-7 21 959 14 6292
    preribosome, small subunit precursor 6.369E-7 21 6 3 6292
    Noc4p-Nop14p complex 1.0611E-5 21 2 2 6292
    membrane 1.7965E-5 21 1198 13 6292
    nucleus 4.8402E-5 21 2041 16 6292
    Noc complex 1.0547E-4 21 5 2 6292
    small-subunit processome 1.5788E-4 21 6 2 6292
    intracellular organelle part 2.2313E-4 21 2282 16 6292
    organelle part 2.2313E-4 21 2282 16 6292
    nucleolar part 4.1557E-4 21 45 3 6292
    90S preribosome 1.4001E-3 21 17 2 6292
    intracellular part 6.1098E-3 21 4938 21 6292
    intracellular 7.149E-3 21 4975 21 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ribosome biogenesis 1.957E-27 21 346 21 6292
    ribonucleoprotein complex biogenesis 1.0515E-26 21 374 21 6292
    rRNA processing 3.2938E-26 21 128 17 6292
    rRNA metabolic process 1.1222E-25 21 137 17 6292
    maturation of SSU-rRNA 8.5614E-25 21 59 14 6292
    ncRNA processing 3.3413E-22 21 215 17 6292
    cellular component biogenesis 5.9672E-21 21 694 21 6292
    ncRNA metabolic process 7.5352E-21 21 257 17 6292
    RNA processing 6.4275E-18 21 380 17 6292
    RNA metabolic process 3.4133E-11 21 954 17 6292
    gene expression 4.3033E-9 21 1283 17 6292
    nucleic acid metabolic process 2.0801E-8 21 1415 17 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.0475E-7 21 1566 17 6292
    cellular nitrogen compound metabolic process 7.2099E-7 21 1770 17 6292
    nitrogen compound metabolic process 8.6688E-7 21 1791 17 6292
    rRNA modification 2.5324E-5 21 18 3 6292
    cellular macromolecule metabolic process 3.6212E-5 21 2285 17 6292
    macromolecule metabolic process 5.4715E-5 21 2349 17 6292
    ribosomal small subunit biogenesis 7.9315E-5 21 26 3 6292
    cellular process 6.1031E-4 21 4426 21 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.0949E-4 21 13 2 6292
    primary metabolic process 1.1355E-3 21 2896 17 6292
    RNA modification 1.5194E-3 21 70 3 6292
    cellular metabolic process 2.1572E-3 21 3033 17 6292
    metabolic process 3.7241E-3 21 3157 17 6292
    ncRNA 5'-end processing 9.9809E-3 21 3 1 6292
    endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 9.9809E-3 21 3 1 6292
    endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 9.9809E-3 21 3 1 6292
    rRNA 5'-end processing 9.9809E-3 21 3 1 6292
    RNA 5'-end processing 9.9809E-3 21 3 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    snoRNA binding 1.0693E-26 21 31 13 6292
    RNA binding 9.7778E-12 21 367 13 6292
    nucleic acid binding 1.7036E-8 21 666 13 6292
    binding 6.1025E-6 21 1294 14 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle