Protein Overview: TAF11

General Information:
Name(s) found:	TAF11 / YML015C [SGD]
Description(s) found: Found 28 descriptions. SHOW ALL	TFIID subunit (40 kDa), involved in RNA polymerase II transcription initiation, similar to histone H3 with atypical histone fold motif of Spt3-like transcription factors [SGD]
Organism:	Saccharomyces cerevisiae
Length:	346 amino acids
Gene Ontology:
Cellular Component:	transcription factor TFIID complex [IDA][TAS]
Biological Process:	regulation of transcription involved in G1 phase of mitotic cell cycle [IPI ] transcription initiation from RNA polymerase II promoter [TAS ]
Molecular Function:	general RNA polymerase II transcription factor activity [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTEPQGPLDT IPKVNYPPIL TIANYFSTKQ MIDQVISEDQ DYVTWKLQNL RTGGTSINNQ  60
   61 LNKYPKYKYQ KTRINQQDPD SINKVPENLI FPQDILQQQT QNSNYEDTNT NEDENEKLAQ 120
  121 DEQFKLLVTN LDKDQTNRFE VFHRTSLNKT QVKKLASTVA NQTISENIRV FLQAVGKIYA 180
  181 GEIIELAMIV KNKWLTSQMC IEFDKRTKIG YKLKKYLKKL TFSIIENQQY KQDYQSDSVP 240
  241 EDEPDFYFDD EEVDKRETTL GNSLLQSKSL QQSDHNSQDL KLQLIEQYNK LVLQFNKLDV 300
  301 SIEKYNNSPL LPEHIREAWR LYRLQSDTLP NAYWRTQGEG QGSMFR

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		ADA2 GCN5 HFI1 NGG1 SGF73 SPT15 SPT3 SPT7 SPT8 TAF1 TAF10 TAF11 TAF12 TAF3 TAF4 TAF5 TAF6 TAF7 TAF9
View Details	(MIPS) Mewes HW, et al. (2004)		TAF1 TAF10 TAF11 TAF12 TAF13 TAF14 TAF2 TAF3 TAF5 TAF6 TAF7 TAF9
View Details	Krogan NJ, et al. (2006)		ADA2 AHC1 AHC2 FMP40 GCN5 HFI1 MSS4 NGG1 PDR15 RAD59 REV3 SGF11 SGF29 SGF73 SNL1 SPT20 SPT3 SPT7 SPT8 TAF1 TAF10 TAF11 TAF12 TAF13 TAF3 TAF4 TAF5 TAF6 TAF7 TAF9 UBP8 YMR007W
View Details	Gavin AC, et al. (2006)		SPT15 TAF1 TAF11 TAF12 TAF3 TAF4 TAF5 TAF9
View Details	Gavin AC, et al. (2002)		ADA2 ADH1 CLU1 FUN19 GCN5 HEM13 HFI1 KAP114 KAP123 MED4 MES1 MNN4 MOT1 MYO1 MYO4 NGG1 NOP1 PFK2 PSK1 PTC1 PUF6 RPB2 RPN9 RPO21 RPT5 RVB2 SGF29 SGF73 SIN3 SIN4 SPT15 SPT20 SPT7 SPT8 TAF1 TAF10 TAF11 TAF12 TAF13 TAF14 TAF2 TAF3 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TBF1 TEF4 UBP8 VAS1 VPS1
View Details	Qiu et al. (2008)		ADA2 GAL11 GCN5 HFI1 MED4 NGG1 PGD1 SGF73 SPT15 SPT20 SPT3 SPT7 TAF1 TAF10 TAF11 TAF12 TAF13 TAF14 TAF2 TAF3 TAF5 TAF6 TAF7 TAF8 TAF9 TFA1 TFB4 TFB5 TRA1

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	CTF13	TAF11	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..113]	deduced	N/A	No confident structure predictions are available.
2	View Details	[114..238]	PSI-BLAST	100.0	TAF(II)28
3	View Details	[239..346]	deduced	N/A	Confident ab initio structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2