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Bait Protein: VAM3
Organism: Saccharomyces cerevisiae
Publication: Hao Xu , Youngsoo Jun, James Thompson, John Yates and William Wickner (2010) HOPS Prevents the Disassembly of Trans-SNARE Complexes by Sec17p/Sec18p during Membrane Fusion [In Press]
Comments: Sample: HX12 - trans-SNARE complex formation and fusion are inhibited (control).

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  Hit Protein Protein Desc Sequence Count Spectrum Count Sequence Coverage NSAF Mol. Wt.
[View Peptides]   GDI1 GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by regulating the dissoc... 42 173 68.1% 0.0504 51206
[View Peptides]   VAM3 Syntaxin-related protein required for vacuolar assembly; functions with Vam7p in vacuolar protein tr... 21 179 43.1% 0.0832 32498
[View Peptides]   RPP2A Ribosomal protein P2 alpha, a component of the ribosomal stalk, which is involved in the interaction... 3 8 36.8% 0.00992 10746
[View Peptides]   RPP2B Ribosomal protein P2 beta, a component of the ribosomal stalk, which is involved in the interaction ... 3 9 36.4% 0.0108 11050
[View Peptides]   PDA1 E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex, catalyzes the direct oxidative decarbo... 18 47 35.5% 0.0147 46343
[View Peptides]   SEC17 Peripheral membrane protein required for vesicular transport between ER and Golgi, the 'priming' ste... 9 27 35.3% 0.0122 32803
[View Peptides]   VTI1 Protein involved in cis-Golgi membrane traffic; v-SNARE that interacts with two t-SNARES, Sed5p and ... 5 21 32.3% 0.0127 24668
[View Peptides]   SNA3 Integral membrane protein localized to vacuolar intralumenal vesicles, computational analysis of lar... 2 6 31.6% 0.00593 15199
[View Peptides]   LAT1 Dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex, which catalyzes... 12 27 27.8% 0.00736 51818
[View Peptides]   CDC19 Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvat... 9 24 27.0% 0.00631 54545
[View Peptides]   SHM2 Cytosolic serine hydroxymethyltransferase, converts serine to glycine plus 5,10 methylenetetrahydrof... 11 19 26.7% 0.00533 52219
[View Peptides]   PDB1 E1 beta subunit of the pyruvate dehydrogenase (PDH) complex, which is an evolutionarily-conserved mu... 7 28 26.2% 0.0101 40054
[View Peptides]   PHO8 Repressible alkaline phosphatase, a glycoprotein localized to the vacuole; regulated by levels of in... 13 43 24.4% 0.00999 63004
[View Peptides]   KAR2 ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding i... 15 42 23.8% 0.0081 74468
[View Peptides]   PPN1 Vacuolar endopolyphosphatase with a role in phosphate metabolism; functions as a homodimer 12 28 23.7% 0.00546 78344
[View Peptides]   PDX1 Dihydrolipoamide dehydrogenase (E3)-binding protein (E3BP) of the mitochondrial pyruvate dehydrogena... 7 13 23.7% 0.00417 45362
[View Peptides]   SEC18 ATPase required for vesicular transport between ER and Golgi, the 'priming' step in homotypic vacuol... 13 23 23.6% 0.00399 84056
[View Peptides]   GOS1 v-SNARE protein involved in Golgi transport, homolog of the mammalian protein GOS-28/GS28 3 4 22.9% 0.00236 25395
[View Peptides]   PIL1 Primary component of eisosomes, which are large immobile cell cortex structures associated with endo... 5 7 22.4% 0.00271 38349
[View Peptides]   IES5 Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions 2 2 21.6% 0.0021 14312
[View Peptides]   CCC1 Putative vacuolar Fe2+/Mn2+ transporter; suppresses respiratory deficit of yfh1 mutants, which lack ... 5 8 19.9% 0.00327 34250
[View Peptides]   YNR061C Putative protein of unknown function 3 7 19.6% 0.0042 24317
[View Peptides]   VTC3 Subunit of the vacuolar transporter chaperone (VTC) complex involved in membrane trafficking, vacuol... 12 23 19.0% 0.00362 96553
[View Peptides]   VAM7 Component of the vacuole SNARE complex involved in vacuolar morphogenesis; SNAP-25 homolog; function... 5 16 18.7% 0.00666 36711
[View Peptides]   GYP1 Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in vivo) and for Ypt1p, ... 14 38 18.4% 0.00784 73289
[View Peptides]   PEP12 Target membrane receptor (t-SNARE) for vesicular intermediates traveling between the Golgi apparatus... 4 5 18.1% 0.00228 33006
[View Peptides]   PSA1 GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesizes GDP-mannose from ... 4 9 18.0% 0.00328 39566
[View Peptides]   YNL058C Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th... 3 8 18.0% 0.00333 35046
[View Peptides]   URA2 Bifunctional carbamoylphosphate synthetase (CPSase)-aspartate transcarbamylase (ATCase), catalyzes t... 29 46 17.7% 0.00273 245123
[View Peptides]   FAA4 Long chain fatty acyl-CoA synthetase, activates imported fatty acids with a preference for C12:0-C16... 9 21 17.3% 0.00398 77267
[View Peptides]   CPS1 Vacuolar carboxypeptidase yscS; expression is induced under low-nitrogen conditions 10 15 16.8% 0.00342 64597
[View Peptides]   FRA1 Protein involved in negative regulation of transcription of iron regulon; forms an iron independent ... 10 23 16.4% 0.00404 84924
[View Peptides]   KTR6 Probable mannosylphosphate transferase involved in the synthesis of core oligosaccharides in protein... 4 5 15.5% 0.00147 52128
[View Peptides]   LPD1 Dihydrolipoamide dehydrogenase, the lipoamide dehydrogenase component (E3) of the pyruvate dehydroge... 6 7 15.4% 0.00184 54010
[View Peptides]   NVJ1 Nuclear envelope protein, anchored to the nuclear inner membrane, that interacts with the vacuolar m... 3 5 15.3% 0.00205 36421
[View Peptides]   YPK9 Vacuolar protein with a possible role in sequestering heavy metals; has similarity to the type V P-t... 17 42 15.1% 0.00375 166749
[View Peptides]   RHR2 Constitutively expressed isoform of DL-glycerol-3-phosphatase; involved in glycerol biosynthesis, in... 3 5 15.1% 0.00243 30439
[View Peptides]   TSA1 Thioredoxin peroxidase, acts as both a ribosome-associated and free cytoplasmic antioxidant; self-as... 2 2 14.8% 0.00134 21590
[View Peptides]   SAC1 Phosphatidylinositol phosphate (PtdInsP) phosphatase involved in hydrolysis of PtdIns[4]P; transmemb... 6 8 14.6% 0.00169 71125
[View Peptides]   RNA1 GTPase activating protein (GAP) for Gsp1p, involved in nuclear transport 4 4 14.5% 0.00129 45816
[View Peptides]   TUF1 Mitochondrial translation elongation factor Tu; comprises both GTPase and guanine nucleotide exchang... 4 6 14.4% 0.0018 47972
[View Peptides]   NYV1 v-SNARE component of the vacuolar SNARE complex involved in vesicle fusion; inhibits ATP-dependent C... 3 6 14.2% 0.00312 28964
[View Peptides]   YNL217W Hypothetical protein 5 9 14.1% 0.00363 37151
[View Peptides]   VAC8 Phosphorylated and palmitoylated vacuolar membrane protein that interacts with Atg13p, required for ... 6 15 14.0% 0.00341 63208
[View Peptides]   DAP2 Dipeptidyl aminopeptidase, synthesized as a glycosylated precursor; localizes to the vacuolar membra... 10 23 13.9% 0.0037 93404
[View Peptides]   YDR089W Protein of unknown function; deletion confers resistance to Nickel 9 21 13.8% 0.00318 98712
[View Peptides]   DID4 Class E Vps protein of the ESCRT-III complex, required for sorting of integral membrane proteins int... 3 3 13.8% 0.0017 26291
[View Peptides]   FKS1 Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alternate catalytic sub... 19 44 13.6% 0.00308 214849
[View Peptides]   TUB2 Beta-tubulin; associates with alpha-tubulin (Tub1p and Tub3p) to form tubulin dimer, which polymeriz... 5 8 13.6% 0.0023 50923
[View Peptides]   VTC2 Subunit of the vacuolar transporter chaperone (VTC) complex involved in membrane trafficking, vacuol... 9 13 13.5% 0.00206 95441
[View Peptides]   VTC4 Vacuolar membrane polyphosphate polymerase; subunit of the vacuolar transporter chaperone (VTC) comp... 11 20 13.5% 0.00365 83155
[View Peptides]   SKG6 Integral membrane protein that localizes primarily to growing sites such as the bud tip or the cell ... 6 11 13.5% 0.00197 81849
[View Peptides]   YPT7 Rab family GTPase; GTP-binding protein of the rab family; required for homotypic fusion event in vac... 2 3 13.5% 0.0019 23043
[View Peptides]   NOP56 Essential evolutionarily-conserved nucleolar protein component of the box C/D snoRNP complexes that ... 4 9 13.3% 0.00235 56864
[View Peptides]   TCP1 Alpha subunit of chaperonin-containing T-complex, which mediates protein folding in the cytosol; inv... 6 9 13.2% 0.00212 60481
[View Peptides]   VPH1 Subunit a of vacuolar-ATPase V0 domain, one of two isoforms (Vph1p and Stv1p); Vph1p is located in V... 7 18 13.0% 0.00282 95529
[View Peptides]   TLG1 Essential t-SNARE that forms a complex with Tlg2p and Vti1p and mediates fusion of endosome-derived ... 2 4 12.9% 0.00235 25817
[View Peptides]   YCF1 Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detox... 16 30 12.7% 0.0026 171120
[View Peptides]   KRE6 Protein required for beta-1,6 glucan biosynthesis; putative beta-glucan synthase; appears functional... 6 8 12.5% 0.00146 80123
[View Peptides]   SMF3 Putative divalent metal ion transporter involved in iron homeostasis; transcriptionally regulated by... 5 7 12.5% 0.00195 51775
[View Peptides]   RPP0 Conserved ribosomal protein P0 similar to rat P0, human P0, and E. coli L10e; shown to be phosphoryl... 3 6 12.5% 0.00253 33717
[View Peptides]   HSP60 Tetradecameric mitochondrial chaperonin required for ATP-dependent folding of precursor polypeptides... 5 8 12.4% 0.00184 60752
[View Peptides]   ROT1 Molecular chaperone involved in protein folding in the ER; mutation causes defects in cell wall synt... 2 3 12.1% 0.00154 28908
[View Peptides]   VMA6 Subunit d of the five-subunit V0 integral membrane domain of vacuolar H+-ATPase (V-ATPase), an elect... 3 8 11.9% 0.00305 39791
[View Peptides]   NPL3 RNA-binding protein that promotes elongation, regulates termination, and carries poly(A) mRNA from n... 3 6 11.8% 0.00191 45407
[View Peptides]   SNF7 One of four subunits of the endosomal sorting complex required for transport III (ESCRT-III); involv... 2 3 11.7% 0.00164 26987
[View Peptides]   HMG1 One of two isozymes of HMG-CoA reductase that catalyzes the conversion of HMG-CoA to mevalonate, whi... 10 16 11.6% 0.002 115625
[View Peptides]   PHO90 Low-affinity phosphate transporter; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthet... 7 10 11.6% 0.00149 97689
[View Peptides]   MNN11 Subunit of a Golgi mannosyltransferase complex that also contains Anp1p, Mnn9p, Mnn10p, and Hoc1p, a... 4 4 11.4% 0.00125 47801
[View Peptides]   VAM6 Vacuolar protein that plays a critical role in the tethering steps of vacuolar membrane fusion by fa... 9 16 11.3% 0.00201 122881
[View Peptides]   DBP2 Essential ATP-dependent RNA helicase of the DEAD-box protein family, involved in nonsense-mediated m... 5 10 11.0% 0.00241 60999
[View Peptides]   HMX1 ER localized, heme-binding peroxidase involved in the degradation of heme; does not exhibit heme oxy... 2 5 11.0% 0.00207 37179
[View Peptides]   MNN1 Alpha-1,3-mannosyltransferase, integral membrane glycoprotein of the Golgi complex, required for add... 7 14 10.9% 0.00242 88529
[View Peptides]   YME1 Catalytic subunit of the mitochondrial inner membrane i-AAA protease complex, which is responsible f... 7 13 10.8% 0.00229 81772
[View Peptides]   MNR2 Vacuolar membrane protein required for magnesium homeostasis; putative magnesium transporter; has si... 8 17 10.7% 0.00231 109736
[View Peptides]   PRM5 Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrit... 3 4 10.7% 0.00165 34651
[View Peptides]   IVY1 Phospholipid-binding protein that interacts with both Ypt7p and Vps33p, may partially counteract the... 3 9 10.6% 0.00261 49976
[View Peptides]   VAN1 Component of the mannan polymerase I, which contains Van1p and Mnn9p and is involved in the first st... 3 5 10.3% 0.00123 61092
[View Peptides]   PHO84 High-affinity inorganic phosphate (Pi) transporter and low-affinity manganese transporter; regulated... 6 13 10.2% 0.00291 64382
[View Peptides]   HXT3 Low affinity glucose transporter of the major facilitator superfamily, expression is induced in low ... 4 6 10.1% 0.00139 62558
[View Peptides]   TUB1 Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form... 3 7 10.1% 0.00206 49800
[View Peptides]   NOP1 Nucleolar protein, component of the small subunit processome complex, which is required for processi... 3 5 10.1% 0.00201 34465
[View Peptides]   ADE5,7 Bifunctional enzyme of the 'de novo' purine nucleotide biosynthetic pathway, contains aminoimidazole... 6 16 10.0% 0.00262 86068
[View Peptides]   CCT8 Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of... 4 7 9.7% 0.00162 61662
[View Peptides]   YBT1 Transporter of the ATP-binding cassette (ABC) family involved in bile acid transport; similar to mam... 13 17 9.5% 0.00135 189161
[View Peptides]   VMA2 Subunit B of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), a... 4 5 9.5% 0.00127 57749
[View Peptides]   PDC1 Major of three pyruvate decarboxylase isozymes, key enzyme in alcoholic fermentation, decarboxylates... 3 4 9.4% 9.34E-4 61495
[View Peptides]   YBR287W Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the ER; YBR... 3 4 9.4% 0.00123 47506
[View Peptides]   GSF2 ER localized integral membrane protein that may promote secretion of certain hexose transporters, in... 2 2 9.4% 6.52E-4 45870
[View Peptides]   LCB4 Sphingoid long-chain base kinase, responsible for synthesis of long-chain base phosphates, which fun... 4 5 9.3% 0.00105 69639
[View Peptides]   ENA2 P-type ATPase sodium pump, involved in Na+ efflux to allow salt tolerance; likely not involved in Li... 7 10 9.2% 0.0012 120317
[View Peptides]   ENA1 P-type ATPase sodium pump, involved in Na+ and Li+ efflux to allow salt tolerance 7 10 9.2% 0.0012 120357
[View Peptides]   ENA5 Protein with similarity to P-type ATPase sodium pumps, member of the Na+ efflux ATPase family 7 10 9.2% 0.0012 120296
[View Peptides]   MAM3 Protein required for normal mitochondrial morphology, has similarity to hemolysins 4 5 9.2% 9.31E-4 77712
[View Peptides]   NOP58 Protein involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis; component of the ... 3 4 9.2% 0.00103 56956
[View Peptides]   YJL132W Putative protein of unknown function; localizes to the membrane fraction; possible Zap1p-regulated t... 5 6 9.1% 0.00105 84466
[View Peptides]   GPA1 GTP-binding alpha subunit of the heterotrimeric G protein that couples to pheromone receptors; negat... 3 6 9.1% 0.00167 54076
[View Peptides]   PDI1 Protein disulfide isomerase, multifunctional protein resident in the endoplasmic reticulum lumen, es... 3 8 9.0% 0.00201 58227
[View Peptides]   PMA1 Plasma membrane H+-ATPase, pumps protons out of the cell; major regulator of cytoplasmic pH and plas... 6 12 8.9% 0.00172 99619
[View Peptides]   PEP3 Component of CORVET tethering complex; vacuolar peripheral membrane protein that promotes vesicular ... 7 12 8.6% 0.00172 107398
[View Peptides]   CCT7 Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of... 3 3 8.4% 7.17E-4 59736
[View Peptides]   BPT1 ABC type transmembrane transporter of MRP/CFTR family, found in vacuolar membrane, involved in the t... 11 13 8.3% 0.0011 176873
[View Peptides]   EFT2, EFT1 Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein s... 5 5 8.3% 7.81E-4 93289
[View Peptides]   TFP1 Subunit A of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase; protein prec... 6 8 8.2% 9.82E-4 118637
[View Peptides]   YOL019W Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell pe... 3 3 8.2% 7.16E-4 60901
[View Peptides]   SEC63 Essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/Bi... 5 6 8.0% 0.00119 75345
[View Peptides]   SCJ1 One of several homologs of bacterial chaperone DnaJ, located in the ER lumen where it cooperates wit... 2 3 8.0% 0.00105 41543
[View Peptides]   YCK3 Palmitoylated, vacuolar membrane-localized casein kinase I isoform; negatively regulates vacuole fus... 3 6 7.8% 0.00151 60261
[View Peptides]   PGK1 3-phosphoglycerate kinase, catalyzes transfer of high-energy phosphoryl groups from the acyl phospha... 2 2 7.7% 6.32E-4 44738
[View Peptides]   SYG1 Plasma membrane protein of unknown function; truncation and overexpression suppresses lethality of G... 4 5 7.5% 7.29E-4 104217
[View Peptides]   VNX1 Low affinity vacuolar membrane localized monovalent cation/H+ antiporter; member of the calcium exch... 5 9 7.5% 0.0013 102499
[View Peptides]   VBA4 Protein of unknown function with proposed role as a basic amino acid permease based on phylogeny; GF... 4 9 7.3% 0.00154 85683
[View Peptides]   VPS41 Vacuolar membrane protein that is a subunit of the homotypic vacuole fusion and vacuole protein sort... 5 11 7.2% 0.00146 113412
[View Peptides]   FET5 Multicopper oxidase, integral membrane protein with similarity to Fet3p; may have a role in iron tra... 4 8 7.1% 0.00169 70880
[View Peptides]   YDL180W Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th... 3 4 7.1% 9.61E-4 62288
[View Peptides]   GSC2 Catalytic subunit of 1,3-beta-glucan synthase, involved in formation of the inner layer of the spore... 10 20 7.0% 0.00139 216988
[View Peptides]   EPS1 ER protein with chaperone and co-chaperone activity, involved in retention of resident ER proteins; ... 3 4 7.0% 7.5E-4 81219
[View Peptides]   KTR1 Alpha-1,2-mannosyltransferase involved in O- and N-linked protein glycosylation; type II membrane pr... 2 4 6.9% 0.00134 46022
[View Peptides]   TEF1, TEF2 Translational elongation factor EF-1 alpha; also encoded by TEF2; functions in the binding reaction ... 3 8 6.8% 0.0023 50033
[View Peptides]   SAM1 S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom ... 2 3 6.8% 0.00103 41818
[View Peptides]   PHO91 Low-affinity phosphate transporter of the vacuolar membrane; deletion of pho84, pho87, pho89, pho90,... 9 14 6.7% 0.00206 99490
[View Peptides]   ECM14 Putative metalloprotease with similarity to the zinc carboxypeptidase family, required for normal ce... 2 2 6.7% 6.11E-4 49829
[View Peptides]   RMD8 Cytosolic protein required for sporulation 3 7 6.6% 0.00139 75914
[View Peptides]   PGC1 Phosphatidyl Glycerol phospholipase C; regulates the phosphatidylglycerol (PG) content via a phospho... 2 2 6.5% 8.19E-4 37070
[View Peptides]   VAC7 Integral vacuolar membrane protein involved in vacuole inheritance and morphology; activates Fab1p k... 7 13 6.4% 0.00147 128140
[View Peptides]   PTR2 Integral membrane peptide transporter, mediates transport of di- and tri-peptides; conserved protein... 2 2 6.3% 4.37E-4 68044
[View Peptides]   ZRC1 Vacuolar membrane zinc transporter, transports zinc from the cytosol into the vacuole for storage; a... 2 8 6.3% 0.00238 48345
[View Peptides]   YER138C Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... 8 15 6.1% 0.00112 198561
[View Peptides]   CHS2 Chitin synthase II; catalyzes transfer of N-acetylglucosamine (GlcNAc) to chitin upon activation of ... 4 7 6.1% 9.56E-4 109882
[View Peptides]   RMD1 Cytoplasmic protein required for sporulation 2 2 6.0% 6.11E-4 49932
[View Peptides]   ERV46 Protein localized to COPII-coated vesicles, forms a complex with Erv41p; involved in the membrane fu... 2 4 6.0% 0.00127 46235
[View Peptides]   CCT4 Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of... 2 3 5.9% 7.47E-4 57604
[View Peptides]   OLE1 Delta(9) fatty acid desaturase, required for monounsaturated fatty acid synthesis and for normal dis... 2 3 5.7% 7.73E-4 58403
[View Peptides]   KRE2 Alpha1,2-mannosyltransferase of the Golgi involved in protein mannosylation 2 4 5.7% 0.00119 51387
[View Peptides]   PMC1 Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions; prevents growth inhibition by activ... 5 9 5.6% 0.00101 130861
[View Peptides]   YDL199C Putative transporter, member of the sugar porter family 2 2 5.5% 3.83E-4 77501
[View Peptides]   RSP5 E3 ubiquitin ligase of the NEDD4 family; involved in regulating many cellular processes, including M... 4 4 5.4% 6.5E-4 91816
[View Peptides]   VTC1 Subunit of the vacuolar transporter chaperone (VTC) complex involved in membrane trafficking, vacuol... 2 2 5.4% 0.00204 14371
[View Peptides]   VPS16 Subunit of the vacuole fusion and protein sorting HOPS complex and the CORVET tethering complex; par... 3 3 5.3% 4.94E-4 92741
[View Peptides]   EAR1 Specificity factor required for Rsp5p-dependent ubiquitination and sorting of specific cargo protein... 2 2 5.3% 4.78E-4 62532
[View Peptides]   YGR125W Putative protein of unknown function; deletion mutant has decreased rapamycin resistance but normal ... 4 6 5.2% 7.61E-4 116971
[View Peptides]   VPS33 ATP-binding protein that is a subunit of the HOPS complex and of the CORVET tethering complex; essen... 3 4 5.2% 7.61E-4 79271
[View Peptides]   FPS1 Plasma membrane channel, member of major intrinsic protein (MIP) family; involved in efflux of glyce... 2 4 5.2% 7.86E-4 73877
[View Peptides]   ERG1 Squalene epoxidase, catalyzes the epoxidation of squalene to 2,3-oxidosqualene; plays an essential r... 2 2 5.2% 5.3E-4 55126
[View Peptides]   CHS1 Chitin synthase I, requires activation from zymogenic form in order to catalyze the transfer of N-ac... 4 5 5.0% 5.81E-4 129919
[View Peptides]   DBP3 Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis 2 2 5.0% 5.03E-4 58827
[View Peptides]   SKT5 Activator of Chs3p (chitin synthase III), recruits Chs3p to the bud neck via interaction with Bni4p;... 2 2 4.9% 3.78E-4 77066
[View Peptides]   ERG11 Lanosterol 14-alpha-demethylase, catalyzes the C-14 demethylation of lanosterol to form 4,4''-dimeth... 2 2 4.9% 4.96E-4 60720
[View Peptides]   PFK1 Alpha subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaer... 3 3 4.7% 4.0E-4 107970
[View Peptides]   SSH4 Specificity factor required for Rsp5p-dependent ubiquitination and sorting of cargo proteins at the ... 2 2 4.7% 4.54E-4 65061
[View Peptides]   TGL4 Multifunctional triacylglycerol lipase, steryl ester hydrolase, and Ca2+-independent phospholipase A... 3 3 4.6% 4.33E-4 102716
[View Peptides]   NOG1 Putative GTPase that associates with free 60S ribosomal subunits in the nucleolus and is required fo... 2 2 4.6% 4.06E-4 74410
[View Peptides]   DED1 ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase, required for translation initiation of all ye... 2 4 4.5% 8.71E-4 65553
[View Peptides]   MNT2 Mannosyltransferase involved in adding the 4th and 5th mannose residues of O-linked glycans 2 2 4.5% 4.71E-4 64853
[View Peptides]   LYP1 Lysine permease; one of three amino acid permeases (Alp1p, Can1p, Lyp1p) responsible for uptake of c... 2 3 4.4% 6.45E-4 68090
[View Peptides]   SWH1 Protein similar to mammalian oxysterol-binding protein; contains ankyrin repeats; localizes to the G... 3 3 4.3% 3.32E-4 135070
[View Peptides]   PEP5 Component of CORVET tethering complex; peripheral vacuolar membrane protein required for protein tra... 4 8 4.2% 0.00102 117477
[View Peptides]   GRS1 Cytoplasmic and mitochondrial glycyl-tRNA synthase that ligates glycine to the cognate anticodon bea... 2 2 4.2% 3.94E-4 75411
[View Peptides]   KOG1 Subunit of TORC1, a rapamycin-sensitive complex involved in growth control that contains Tor1p or To... 4 6 4.1% 5.07E-4 177608
[View Peptides]   YLR241W Putative protein of unknown function, may be involved in detoxification 3 4 4.1% 6.72E-4 89344
[View Peptides]   PDR5 Plasma membrane ATP-binding cassette (ABC) transporter, multidrug transporter actively regulated by ... 4 6 3.8% 5.22E-4 170437
[View Peptides]   YVC1 Vacuolar cation channel, mediates release of Ca(2+) from the vacuole in response to hyperosmotic sho... 2 3 3.7% 5.84E-4 77953
[View Peptides]   MHP1 Microtubule-associated protein involved in assembly and stabilization of microtubules; overproductio... 3 3 3.6% 2.82E-4 155207
[View Peptides]   SEY1 GTPase with a role in ER morphology; interacts physically and genetically with Yop1p and Rtn1p; poss... 2 3 3.6% 5.08E-4 89433
[View Peptides]   FRE1 Ferric reductase and cupric reductase, reduces siderophore-bound iron and oxidized copper prior to u... 2 2 3.5% 3.83E-4 78854
[View Peptides]   CHS3 Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for ... 2 2 3.4% 2.26E-4 131601
[View Peptides]   IRC8 Bud tip localized protein of unknown function; mRNA is targeted to the bud by a She2p dependent tran... 2 2 3.4% 3.2E-4 91256
[View Peptides]   KRE33 Essential protein, required for biogenesis of the small ribosomal subunit; heterozygous mutant shows... 2 2 3.1% 2.49E-4 119347
[View Peptides]   TRE2 Protein that functions with Tre1p to regulate ubiquitylation and vacuolar degradation of the metal t... 2 4 3.0% 6.5E-4 91995
[View Peptides]   DIP5 Dicarboxylic amino acid permease, mediates high-affinity and high-capacity transport of L-glutamate ... 3 4 3.0% 8.65E-4 68098
[View Peptides]   YDR338C Putative protein of unknown function 2 4 2.9% 7.57E-4 77846
[View Peptides]   YBR235W Putative ion transporter, similar to mammalian electroneutral Na(+)-(K+)-C1- cotransporter family; Y... 2 2 2.8% 2.35E-4 123998
[View Peptides]   HMG2 One of two isozymes of HMG-CoA reductase that convert HMG-CoA to mevalonate, a rate-limiting step in... 2 3 2.8% 3.77E-4 115692
[View Peptides]   RPN1 Non-ATPase base subunit of the 19S regulatory particle of the 26S proteasome; may participate in the... 2 2 2.8% 2.65E-4 109492
[View Peptides]   PEP1 Type I transmembrane sorting receptor for multiple vacuolar hydrolases; cycles between the late-Golg... 3 4 2.5% 3.33E-4 177777
[View Peptides]   YBL104C Putative protein of unknown function, promoter contains multiple GCN4 binding sites 2 2 2.5% 2.53E-4 117636
[View Peptides]   VTH2 Putative membrane glycoprotein with strong similarity to Vth1p and Pep1p/Vps10p, may be involved in ... 2 2 1.9% 1.7E-4 174401
[View Peptides]   VTH1 Putative membrane glycoprotein with strong similarity to Vth2p and Pep1p/Vps10p, may be involved in ... 2 2 1.9% 1.7E-4 174427

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle