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Protein Overview: SO4002

General Information:
Name(s) found: SO4002 [shew_pnnl_plus_contams_psm.fasta]
Description(s) found:
  • sensory transduction histidine kinase [shew_pnnl_plus_contams_psm.fasta]
    • Organism: Shewanella oneidensis
    Length: 1689 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGYGLISLA ILMILSAFKL VNMRTRYLAQ LPLQSNVLWR LFPILFAFLF SSLSVLASPG  60
   61 GQIPLTTAVI DRVSAPTPVL RVSMILSVDT PFNRQIGARA QAAAVDLNIQ LQVLYADGTH 120
  121 DGLMTLGREV MNQGIDGLIF SPVDDFGEAL IREAQKLKIP VVTLRAKLDM LSSAALAELP 180
  181 NFIANVNIND QKSGQLLMHY LLSVDQLNRD VPAVLLIAGP QGYPNVERGV EDVQRFMNSL 240
  241 STRGTLKIAY TDWSVEQALA QFDSAIAAQP ALTTVVTMNA SAAVAVAAKA HQQLGANAPA 300
  301 IGSMIWSESL VQDIKQGKIQ AAITGSEFSG AIALSILFDH LSARGGPSRK GSFVAPLVVI 360
  361 TPNNYQDYES ILDFDPLRLN FRQISQHFNP DLSINELRLA DLLTSEARVN FLKTLTEPEL 420
  421 NFLRQHPSIR VGIEPDGAPI DYVDQAGKHT GLIASYLSEI AKLIPVRFEV QPTQSWGQTL 480
  481 KDFAADKLDM ISLISASEDR KQRILFTDAI GHFPAVIVMR KDAELVDGIE GLFGKTVAVT 540
  541 RGDITEELLR KKYPEINIIA FDRLEDVLST TLASQVDAAV MLLPKAGQSL LSPANKELTI 600
  601 VAPLDDEFEH SIGVRRDWPE LQSILNKALA QIPSSTRAEL DSRWFTVKYD FGMDPQQIKR 660
  661 WAISSAMVIL GLFACFILWN YGLKRELLRR SRMAAQLESS MNKFHALFDS VMDACVIIDK 720
  721 RGVIKECNAA LQTLLGVEDK TALVGTSLTQ FHLADTFMGS AVQIAQSVED VLKQGLLKFE 780
  781 ADITDSQGQS IPAEVTLKSI ELNTERFVLA TYHNLAERRL VDRLIRHERN LLKNVLGMSP 840
  841 IGVWVCVNGT CRYVNAQMTL MTGLEVEHAV ADIFLQPKDY WHYIRELAPE QECITFESKL 900
  901 KGYHGQILDV LFTAYPTFYD GQHANLCWAL DITQEKAIQA ELASAKLQAD AANRAKSDFL 960
  961 ANMSHEIRTP MNAIIGMSYL ALQTDLAEKR KDYIAKVHQA AGSLLNIIND ILDFSKIEAN1020
 1021 KLTVEHIEFD LDEVLTQLNN VIGFKVEENS MRLIYDIATD CPRYFIGDPQ RLGQILLNYC1080
 1081 NNAVKFSPKG SDILLSCQAE LDKQGATLTF CVADDGIGIP LDKQARLFHS FEQGDTSTSR1140
 1141 KYGGTGLGLA ICKRLSELMQ GEVWCESELG QGSRFYLRLH LPLVKPYDLS TQFAALQGES1200
 1201 LSIVGFMPDL SAIYSRFAAR VGMQARTLEM HMALAELSAC TSQHLIMCET NAFEPELLSV1260
 1261 VLANDKLGLL LIGNGSEPVA IQSLVDKHPQ IIAKQHPILL RTLGESLLLL LNRDRAPFGQ1320
 1321 HLEHQSITTL KNQLAGVELL LVEDNYLNQE LAVELLRQAG ARVTVAQHGQ EALTLLAQQS1380
 1381 FDCVLMDGQM PVMDGYEATR LIRAQPQFAD LPIIAMTANA MDSDRERALA AGMNAQINKP1440
 1441 FQVQQLYSTI AQHVSVHSVQ SLPESPEAHD LDKAQLKQGL PLVEELDIDA GLALCNYNAD1500
 1501 LYRHLLTLFV QTGAKLLQNQ QNEFSQDNLS ALRLSLHTLK GVAGNIGAVS LKEDSGRLEA1560
 1561 SLTDISSLQQ LDANIQETVS QEIHLLHAKL QQLLTLLAEW QTVNQPDEAS QSISMTELMR1620
 1621 LFAQLTQNLK EYNTDALSLV ERLSQLTVLQ PQRQLIAELK QATGQFDFSQ GLELAIQLQE1680
 1681 WAQQQLAKE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..408] FFAS03 4.43 Lac repressor (LacR), N-terminal domain; Lac-repressor (lacR) core (C-terminal domain)
    2 View Details [409..648] PSI-BLAST 29.0 Glutamine-binding protein
    3 View Details [649..813] PSI-BLAST 6.39794 Histidine kinase FixL heme domain
    4 View Details [814..934] PSI-BLAST 4.522879 Crystal Structure of the heme PAS sensor domain of Ec DOS (ferric form)
    5 View Details [935..1189] PSI-BLAST 48.522879 Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
    6 View Details [1190..1563] PSI-BLAST 28.30103 Response regulator PleD in complex with c-diGMP
    7 View Details [1564..1689] PSI-BLAST 57.0 Crystal structure of sigm54 activator (AAA+ ATPase) in the inactive state

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  1.78165889081782 bayes_pls_golite062009
  • binding
    		•  1.48949372339203 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.32274201928316 bayes_pls_golite062009
  • transcription factor activity
    		•  1.13498203900589 bayes_pls_golite062009
  • DNA binding
    		•  1.12854649645915 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.03560994231664 bayes_pls_golite062009
  • signal transducer activity
    		•  0.810070503533362 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.810070503533362 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.617592178828761 bayes_pls_golite062009
  • transporter activity
    		•  0.34326281633424 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.197683590925448 bayes_pls_golite062009
  • receptor activity
    		•  0.1130872982653 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.0834296454830339 bayes_pls_golite062009
    2
    Term Confidence Notes
  • anion transmembrane transporter activity
    		•  3.60119288506724 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  3.53292741410046 bayes_pls_golite062009
  • anion transmembrane-transporting ATPase activity
    		•  3.51205087813611 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.80786841862036 bayes_pls_golite062009
  • transporter activity
    		•  2.37767937786605 bayes_pls_golite062009
  • phosphate transmembrane transporter activity
    		•  2.35121899350011 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.19564149972908 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.14027396604232 bayes_pls_golite062009
  • molybdate ion transmembrane transporter activity
    		•  2.02302864315938 bayes_pls_golite062009
  • molybdate transmembrane-transporting ATPase activity
    		•  2.02302864315938 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.98824826924235 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  1.92247368464925 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  1.91778402126342 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  1.91458600392598 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  1.91458600392598 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  1.91424996753266 bayes_pls_golite062009
  • phosphate transmembrane-transporting ATPase activity
    		•  1.66644014680767 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  1.59154512845516 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.51716707550629 bayes_pls_golite062009
  • ATPase activity
    		•  1.44327228942016 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  1.36989838880058 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.33033652028872 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.31993399326424 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.31926578892427 bayes_pls_golite062009
  • binding
    		•  1.29220115989941 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions
    		•  1.06410714245 bayes_pls_golite062009
  • catalytic activity
    		•  1.04475291968158 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.03226687100951 bayes_pls_golite062009
  • sulfate transmembrane transporter activity
    		•  0.9729713541995 bayes_pls_golite062009
  • transcription factor activity
    		•  0.81271953199554 bayes_pls_golite062009
  • DNA binding
    		•  0.7051372893863 bayes_pls_golite062009
  • sulfate transmembrane-transporting ATPase activity
    		•  0.605937181552931 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.579254737490365 bayes_pls_golite062009
  • hydrolase activity
    		•  0.52200036125335 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.361480611994095 bayes_pls_golite062009
    3
    Term Confidence Notes
  • ion transmembrane transporter activity
    		•  1.94020112661684 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.88422125389203 bayes_pls_golite062009
  • binding
    		•  1.79230776794479 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.70629448457771 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.55042643398568 bayes_pls_golite062009
  • DNA binding
    		•  1.54206275665781 bayes_pls_golite062009
  • two-component response regulator activity
    		•  1.45691562840107 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.41817054839611 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  1.31850321187865 bayes_pls_golite062009
  • transcription factor activity
    		•  1.12946889905444 bayes_pls_golite062009
  • protein binding
    		•  1.0133195984081 bayes_pls_golite062009
  • potassium channel activity
    		•  0.93265112299626 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  0.92661046549451 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  0.926512767264521 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  0.92204538811959 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  0.91469735366704 bayes_pls_golite062009
  • ion channel activity
    		•  0.75430461252947 bayes_pls_golite062009
  • cation channel activity
    		•  0.73262554730695 bayes_pls_golite062009
  • gated channel activity
    		•  0.67217953143815 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  0.650205954115699 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.64202076714636 bayes_pls_golite062009
  • channel activity
    		•  0.64202076714636 bayes_pls_golite062009
  • two-component sensor activity
    		•  0.58151911764083 bayes_pls_golite062009
  • protein histidine kinase activity
    		•  0.56538125817883 bayes_pls_golite062009
  • phosphotransferase activity, nitrogenous group as acceptor
    		•  0.518111391350209 bayes_pls_golite062009
  • signal transducer activity
    		•  0.441034662376355 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.441034662376355 bayes_pls_golite062009
  • transporter activity
    		•  0.360938622392148 bayes_pls_golite062009
  • catalytic activity
    		•  0.285447488878019 bayes_pls_golite062009
  • transcription factor binding
    		•  0.24293756478811 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.217804199010847 bayes_pls_golite062009
    4
    Term Confidence Notes
  • ion transmembrane transporter activity
    		•  1.94020112661684 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.88422125389203 bayes_pls_golite062009
  • binding
    		•  1.79230776794479 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.70629448457771 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.55042643398568 bayes_pls_golite062009
  • DNA binding
    		•  1.54206275665781 bayes_pls_golite062009
  • two-component response regulator activity
    		•  1.45691562840107 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.41817054839611 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  1.31850321187865 bayes_pls_golite062009
  • transcription factor activity
    		•  1.12946889905444 bayes_pls_golite062009
  • protein binding
    		•  1.0133195984081 bayes_pls_golite062009
  • potassium channel activity
    		•  0.93265112299626 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  0.92661046549451 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  0.926512767264521 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  0.92204538811959 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  0.91469735366704 bayes_pls_golite062009
  • ion channel activity
    		•  0.75430461252947 bayes_pls_golite062009
  • cation channel activity
    		•  0.73262554730695 bayes_pls_golite062009
  • gated channel activity
    		•  0.67217953143815 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  0.650205954115699 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.64202076714636 bayes_pls_golite062009
  • channel activity
    		•  0.64202076714636 bayes_pls_golite062009
  • two-component sensor activity
    		•  0.58151911764083 bayes_pls_golite062009
  • protein histidine kinase activity
    		•  0.56538125817883 bayes_pls_golite062009
  • phosphotransferase activity, nitrogenous group as acceptor
    		•  0.518111391350209 bayes_pls_golite062009
  • signal transducer activity
    		•  0.441034662376355 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.441034662376355 bayes_pls_golite062009
  • transporter activity
    		•  0.360938622392148 bayes_pls_golite062009
  • catalytic activity
    		•  0.285447488878019 bayes_pls_golite062009
  • transcription factor binding
    		•  0.24293756478811 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.217804199010847 bayes_pls_golite062009
    5 No functions predicted.
    6
    Term Confidence Notes
  • two-component response regulator activity
    		•  7.02872640261738 bayes_pls_golite062009
  • signal transducer activity
    		•  4.51666042720644 bayes_pls_golite062009
  • molecular transducer activity
    		•  4.51666042720644 bayes_pls_golite062009
  • transcription regulator activity
    		•  4.19396540145756 bayes_pls_golite062009
  • protein histidine kinase activity
    		•  2.35011582062573 bayes_pls_golite062009
  • two-component sensor activity
    		•  2.32303301074957 bayes_pls_golite062009
  • phosphotransferase activity, nitrogenous group as acceptor
    		•  2.28838869071567 bayes_pls_golite062009
  • DNA binding
    		•  1.9200042031022 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.7951051076633 bayes_pls_golite062009
  • transcription factor activity
    		•  1.39074763877806 bayes_pls_golite062009
  • binding
    		•  1.22427537074115 bayes_pls_golite062009
  • protein kinase activity
    		•  1.00737355751913 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.811771244977462 bayes_pls_golite062009
  • kinase activity
    		•  0.725824770559857 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.476057209677045 bayes_pls_golite062009
    7 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle