Protein Overview: C79B2_ARATH

General Information:
Name(s) found:	C79B2_ARATH [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|T06101 probable cytochrome P450 T5J17.120 - Arabidopsis thaliana [NCBI NR] gi\|7271050\|emb\|CAB80658.1\| cytochrome P450-like protein [Arabidopsis thaliana] [NCBI NR] gi\|4490746\|emb\|CAB38908.1\| cytochrome P450-like protein [Arabidopsis thaliana] [NCBI NR] gi\|20259281\|gb\|AAM14376.1\| putative cytochrome P450 protein [Arabidopsis thaliana] [NCBI NR] gi\|15236088\|ref\|NP_195705.1\| CYP79B2; electron carrier/ heme binding / iron ion binding / monooxygenase/ oxygen binding [Arabidopsis thaliana] [NCBI NR] gi\|15028135\|gb\|AAK76691.1\| putative cytochrome P450 protein [Arabidopsis thaliana] [NCBI NR] gi\|12644083\|sp\|O81346.2\|C79B2_ARATH RecName: Full=Tryptophan N-hydroxylase 1; AltName: Full=Cytochrome P450 79B2 [NCBI NR] (O81346) Cytochrome P450 79B2 (EC 1.14.-.-) [Swiss-Prot] Tryptophan N-monooxygenase 1 OS=Arabidopsis thaliana GN=CYP79B2 PE=1 SV=2 [Swiss-Prot] putative cytochrome P450 protein [Arabidopsis thaliana]gi\|15028135\|gb\|AAK76691.1\| putative cytochrome P450 protein [Arabidopsis thaliana]gi\|12644083\|sp\|O81346\|C79B_ARATH Cytochrome P450 79B2gi\|7271050\|emb\|CAB80658.1\| cytochrome P450-like protein [Arabi [nrdb_11152004_Chlamydomonas] Tax_Id=3702 Cytochrome P450 79B2 [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta] \| Symbols: CYP79B2 \| CYP79B2 (cytochrome P450, family 79, subfamily B, polypeptide 2); oxygen binding \| chr4:18525305-18527278 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta] cytochrome P450-like protein [Arabidopsis thaliana] [nr-271106-contam.fasta] putative cytochrome P450 protein [Arabidopsis thaliana] [nr-271106-contam.fasta] CYP79B2; heme binding / iron ion binding / monooxygenase/ oxygen binding [Arabidopsis thaliana] [nr-271106-contam.fasta] Cytochrome P450 79B2 [nr-271106-contam.fasta] \| Symbols: CYP79B2 \| cytochrome P450, family 79, subfamily B, polypeptide 2 \| chr4:18525311-18527284 FORWARD LENGTH=541 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
Organism:	Arabidopsis thaliana
Length:	541 amino acids
Gene Ontology:
Cellular Component:	chloroplast [NAS]
Biological Process:	callose deposition in cell wall during defense response [IMP] tryptophan catabolic process [IDA] response to bacterium [IEP] camalexin biosynthetic process [TAS] indoleacetic acid biosynthetic process [IGI][IMP] defense response to oomycetes [IGI] defense response [IMP] defense response to bacterium [IMP]
Molecular Function:	oxygen binding [ISS] iron ion binding [IEA] electron carrier activity [IEA] monooxygenase activity [IEA] heme binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTFTSNSSD LTTTATETSS FSTLYLLSTL QAFVAITLVM LLKKLMTDPN KKKPYLPPGP  60
   61 TGWPIIGMIP TMLKSRPVFR WLHSIMKQLN TEIACVKLGN THVITVTCPK IAREILKQQD 120
  121 ALFASRPLTY AQKILSNGYK TCVITPFGDQ FKKMRKVVMT ELVCPARHRW LHQKRSEEND 180
  181 HLTAWVYNMV KNSGSVDFRF MTRHYCGNAI KKLMFGTRTF SKNTAPDGGP TVEDVEHMEA 240
  241 MFEALGFTFA FCISDYLPML TGLDLNGHEK IMRESSAIMD KYHDPIIDER IKMWREGKRT 300
  301 QIEDFLDIFI SIKDEQGNPL LTADEIKPTI KELVMAAPDN PSNAVEWAMA EMVNKPEILR 360
  361 KAMEEIDRVV GKERLVQESD IPKLNYVKAI LREAFRLHPV AAFNLPHVAL SDTTVAGYHI 420
  421 PKGSQVLLSR YGLGRNPKVW ADPLCFKPER HLNECSEVTL TENDLRFISF STGKRGCAAP 480
  481 ALGTALTTMM LARLLQGFTW KLPENETRVE LMESSHDMFL AKPLVMVGDL RLPEHLYPTV 540
  541 K

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
arachidonic acid monooxygenase activity	6.76823710927794	bayes_pls_golite062009
monooxygenase activity	5.57229509004705	bayes_pls_golite062009
steroid hydroxylase activity	5.04794778387361	bayes_pls_golite062009
arachidonic acid epoxygenase activity	4.80764258881036	bayes_pls_golite062009
electron carrier activity	4.64931978461551	bayes_pls_golite062009
steroid 17-alpha-monooxygenase activity	3.99744233006162	bayes_pls_golite062009
oxygen binding	3.7203678182299	bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	3.68151610133025	bayes_pls_golite062009
demethylase activity	3.40807632433846	bayes_pls_golite062009
sterol 14-demethylase activity	2.94610675710811	bayes_pls_golite062009
retinoic acid 4-hydroxylase activity	2.60901411823382	bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	2.56821164444595	bayes_pls_golite062009
oxysterol 7-alpha-hydroxylase activity	2.36480328243514	bayes_pls_golite062009
oxidoreductase activity	2.35847923992364	bayes_pls_golite062009
1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity	2.30416050662077	bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen	2.15105968497418	bayes_pls_golite062009
ecdysteroid 25-hydroxylase activity	2.0071742914584	bayes_pls_golite062009
retinoid binding	1.91237853759594	bayes_pls_golite062009
vitamin D 24-hydroxylase activity	1.81919676974797	bayes_pls_golite062009
isoprenoid binding	1.78853880472253	bayes_pls_golite062009
flavonoid 3'-monooxygenase activity	1.71233606135238	bayes_pls_golite062009
retinoic acid binding	1.69236715381231	bayes_pls_golite062009
vitamin D3 25-hydroxylase activity	1.65825585934141	bayes_pls_golite062009
vitamin D 25-hydroxylase activity	1.65825585934141	bayes_pls_golite062009
fatty acid (omega-1)-hydroxylase activity	1.65569090470706	bayes_pls_golite062009
corticosterone 18-monooxygenase activity	1.64204907906991	bayes_pls_golite062009
steroid 11-beta-monooxygenase activity	1.64204907906991	bayes_pls_golite062009
ecdysteroid 22-hydroxylase activity	1.58167166311061	bayes_pls_golite062009
testosterone 6-beta-hydroxylase activity	1.4661447981611	bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1.46109575978397	bayes_pls_golite062009
binding	1.2866152532988	bayes_pls_golite062009
25-hydroxycholecalciferol-24-hydroxylase activity	1.06487564122685	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	0.614118857213859	bayes_pls_golite062009
catalytic activity	0.608111453189583	bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors	0.377799149936808	bayes_pls_golite062009
cholesterol monooxygenase (side-chain-cleaving) activity	0.276594551871869	bayes_pls_golite062009
arachidonic acid 11,12-epoxygenase activity	0.0888154993183798	bayes_pls_golite062009

Source: Reynolds et al. 2008. Manuscript submitted

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..541]	PSI-BLAST	102.0	Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8

Protein Overview: C79B2_ARATH

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: