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Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. Catalysis of the removal of a methyl group from a substrate. Catalysis of the removal of a methyl group from a histone. Catalysis of the removal of a methyl group from N-nitrosodimethylamine. Catalysis of the reaction: vanillate + O2 + NADH + H+ = 3,4-dihydroxybenzoate + NAD+ + H2O + formaldehyde. Catalysis of the reaction: obtusifoliol + 3 O2 + 3 NADPH + 3 H+ = 4-alpha-methyl-5-alpha-ergosta-8,14,24(28)-trien-3-beta-ol + formate + 3 NADP+ + 3 H2O. Catalysis of the removal of a methyl group from one or more nucleosides within a RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms. Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. Catalysis of the removal of a methyl group from one or more nucleosides within a DNA molecule. Catalysis of the reaction: vanillate + Co+ = Co3+-CH3 + 3,4-dihydroxybenzoate.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: demethylase activity
Acc: GO:0032451
Aspect: Molecular Function
Desc: Catalysis of the removal of a methyl group from a substrate.
Proteins in PDR annotated with:
   This term: 8 [Search]
   Term or descendants: 51 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0032451 - demethylase activity (interactive image map)

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