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Catalysis of the reaction: dibenzothiophene-5,5-dioxide + O2 + 2 NADH + H+ = 2 NAD+ + H2O + 2'-hydroxybiphenyl-2-sulfinate. Catalysis of the reaction: nitrilotriacetate + NADH + H+ + O2 = NAD+ + H2O + glyoxylate + iminodiacetate. Catalysis of the reaction: 4-methoxybenzoate + donor-H2 + O2 = 4-hydroxybenzoate + formaldehyde + acceptor + H2O. Catalysis of the addition of a hydroxyl group to thalianol ((13R,14R,17E)-podioda-8,17,21-trien-3beta-ol) to create thalian-diol ((13R,14R,17E)-podioda-8,17,21-trien-3beta, ?-diol). Several thalian-diol isomers may be created by the same enzyme because the hydroxyl group may be attached at one of several different available carbons in ring B or C of thalianol (as indicated by the ''?''). Catalysis of an NADPH- and oxygen-dependent reaction that converts linoleic acid to a cis-epoxyoctadecenoic acid. Catalysis of the reaction: coumarin + O2 + NADPH + H+ = hydroxycoumarin + H2O + NADP+. Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. Catalysis of the reaction: L-ornithine + O2 + donor-H2 = N5-hydroxy-L-ornithine + acceptor + H2O. Catalysis of the reaction: 2-hydroxyisobutyrate + 1/2 O2 = 2,3-dihydroxy-2-methyl propionate. Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water. Catalysis of the reaction: 3,7-dimethylocta-1,6-dien-3-ol + donor-H2 + O2 = (E)-3,7-dimethylocta-1,6-dien-3,8-diol + acceptor + H2O. Catalysis of the reaction: alpha-pinene + O2 + 2 H+ + 2 e- = H2O + pinocarveol. Catalysis of the reaction: 3-hydroxybenzoate + donor-H2 + O2 = 2,3-dihydroxybenzoate + acceptor + H2O. Catalysis of the oxidation of alkanes (up to C8) to alcohols and alkenes (up to C5) to epoxides and alcohols in the presence of ammonium ions. Catalysis of the reaction: pregna-4,9(11)-diene-3,20-dione + donor-H2 + O2 = 9,11-alpha-epoxypregn-4-ene-3,20-dione + acceptor + H2O. Catalysis of the reaction: methyl tert-butyl ether + 1/2 O2 = tert-butyl alcohol + formaldehyde. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor. Catalysis of the reaction: 4-nitrocatechol + O2 + 4 e- + 3 H+ = H2O + NO2(-) (nitrite) + 1,2,4-benzenetriol. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced iron-sulfur protein and one other donor, and one atom of oxygen is incorporated into one donor. Catalysis of the reaction: 4-chlorophenoxyacetate + 1/2 O2 = glyoxylate + 4-chlorophenol. Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced pteridine and one other donor, and one atom of oxygen is incorporated into one donor. Catalysis of the reaction: tert-butyl alcohol + 1/2 O2 = 2-methyl-2-hydroxy-1-propanol. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced ascorbate and one other donor, and one atom of oxygen is incorporated into one donor. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and one atom of oxygen is incorporated into one donor. null Catalysis of the reaction: O2 + donor-H2 + androst-4-ene-3,17-dione = H2O + acceptor + 3-oxo-13,17-secoandrost-4-eno-17,13-alpha-lactone. null Catalysis of the reaction: O2 + donor-H2 + vitamin K1 = H2O + acceptor + 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone. Catalysis of the formation of a hydroxyl group on a steroid by incorporation of oxygen from O2. Catalysis of the reaction: estradiol-17-beta + donor-H2 + O2 = 6-beta-hydroxyestradiol-17-beta + acceptor + H2O. Catalysis of the reaction: ferulic acid + NADPH + H+ + O2 = 5-hydroxyferulic acid + H2O + NADP+. Catalysis of the formation of a 2,3-epoxide in squalene. Catalysis of the reaction: 2-hydroxypyridine + donor-H2 + O2 = 2,5-dihydroxypyridine + acceptor + H2O. null Catalysis of the reaction: thiophene-2-carbonyl-CoA + AH2 + O2 = 5-hydroxythiophene-2-carbonyl-CoA + A + H2O. Catalysis of the reaction: progesterone + donor-H2 + O2 = 11-alpha-hydroxyprogesterone + acceptor + H2O. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor. Catalysis of C3-hydroxylation of the beta-ring of various carotenes. null Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. Catalysis of the reaction: progesterone + donor-H2 + O2 = testosterone acetate + acceptor + H2O. Catalysis of the 3-hydroxylation reaction: shikimate or quinate ester of p-coumaric acid + NADPH + H+ + O2 = caffeic acid conjugate (caffeoyl shikimic acid or chlorogenic acid) + H20 + NADP+. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and one oxygen atom is incorporated into a donor. Catalysis of the oxidation of luciferin. The reaction results in light emission as luciferin returns to the ground state after enzymatic oxidation. Catalysis of the hydroxylation of C-24 of 25-hydroxycholecalciferol (25-hydroxyvitamin D3) to form 24(R),25-dihydroxycholecalciferol.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: monooxygenase activity
Acc: GO:0004497
Aspect: Molecular Function
Desc: Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
Synonyms:
  • hydroxylase activity
Proteins in PDR annotated with:
   This term: 773 [Search]
   Term or descendants: 993 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004497 - monooxygenase activity (interactive image map)
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