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Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water. Catalysis of the formation of a hydroxyl group on a steroid by incorporation of oxygen from O2. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced iron-sulfur protein and one other donor, and one atom of oxygen is incorporated into one donor. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor. Catalysis of the reaction: a steroid + reduced adrenal ferredoxin + O2 = an 11-beta-hydroxysteroid + oxidized adrenal ferredoxin + H2O.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: steroid 11-beta-monooxygenase activity
Acc: GO:0004507
Aspect: Molecular Function
Desc: Catalysis of the reaction: a steroid + reduced adrenal ferredoxin + O2 = an 11-beta-hydroxysteroid + oxidized adrenal ferredoxin + H2O.
Synonyms:
  • cytochrome P450 CYP11B2
  • steroid 11beta-hydroxylase activity
  • cytochrome P450 CYP11B1
  • steroid,reduced-adrenal-ferredoxin:oxygen oxidoreductase (11beta-hydroxylating)
  • cytochrome p450 XIB1 activity
  • steroid 11-beta/18-hydroxylase activity
  • oxygenase, steroid 11beta -mono-
  • steroid 11beta/18-hydroxylase activity
  • steroid 11-beta-hydroxylase activity
  • steroid 11beta-monooxygenase activity
Proteins in PDR annotated with:
   This term: 8 [Search]
   Term or descendants: 8 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004507 - steroid 11-beta-monooxygenase activity (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle