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Protein Overview: mrp-1

General Information:
Name(s) found: mrp-1 / CE34565 [WormBase]
Description(s) found:
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  • WBGene00003407 locus:mrp-1 status:Confirmed UniProt:Q7YZW1 protein_id:CCD69452.1 [WormBase]
  • gi|71992080|ref|NP_001024719.1| Multidrug Resistance Protein family member (mrp-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|32453000|gb|AAP82650.1| Multidrug resistance protein family protein 1, isoform d, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • [wormpep111.fasta]
  • Multidrug resistance protein family protein 1, isoform d [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE34565 WBGene00003407 locus:mrp-1 status:Confirmed TR:Q7YZW1 protein_id:AAP82650.1 [wormpep150.fasta]
  • 34565 WBGene00003407 locus:mrp-1 status:Confirmed TR:Q7YZW1 protein_id:AAP82650.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • locus:mrp-1 status:Confirmed TR:Q7YZW1 protein_id:AAP82650.1 [wormpep115.fasta.reversed]
  • CE34565 WBGene00003407 locus:mrp-1 status:Confirmed UniProt:Q7YZW1_CAEEL protein_id:AAP82650.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE34565 WBGene00003407 locus:mrp-1 status:Confirmed UniProt:Q7YZW1_CAEEL protein_id:AAP82650.1| [wormORF-contam.fasta]
  • Multidrug Resistance Protein family member (mrp-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE34565 WBGene00003407 locus:mrp-1 status:Confirmed UniProt:Q7YZW1 protein_id:AAP82650.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE34565 WBGene00003407 locus:mrp-1 status:Confirmed UniProt:Q7YZW1 protein_id:CCD69452.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
    • Organism: Caenorhabditis elegans
    Length: 328 amino acids

    Gene Ontology:
    Cellular Component: Gram-negative-bacterium-type cell wall [IEALink to PubMed article]
    membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    outer membrane-bounded periplasmic space [IEALink to PubMed article]
    Biological Process: protein transport [IEALink to PubMed article]
    transport [IEALink to PubMed article]
    amino acid transport [IEALink to PubMed article]
    nodulation [IEALink to PubMed article]
    cell division [IEALink to PubMed article]
    cobalt ion transport [IEALink to PubMed article]
    lipid transport [IEALink to PubMed article]
    D-methionine transport [IEALink to PubMed article]
    ion transport [IEALink to PubMed article]
    phosphate transport [IEALink to PubMed article]
    nitrate transport [IEALink to PubMed article]
    phosphonate transport [IEALink to PubMed article]
    polyamine transport [IEALink to PubMed article]
    cytochrome complex assembly [IEALink to PubMed article]
    peptide transport [IEALink to PubMed article]
    molybdate ion transport [IEALink to PubMed article]
    Molecular Function: ATPase activity [IEALink to PubMed article]
    phosphate transmembrane transporter activity [IEALink to PubMed article]
    ATPase activity, coupled to transmembrane movement of substances [IEALink to PubMed article]
    nitrate transmembrane transporter activity [IEALink to PubMed article]
    peptide transporter activity [IEALink to PubMed article]
    molybdate ion transmembrane transporter activity [IEALink to PubMed article]
    protein transporter activity [IEALink to PubMed article]
    amino acid transmembrane transporter activity [IEALink to PubMed article]
    cysteine-type peptidase activity [IEALink to PubMed article]
    chloride channel activity [IEALink to PubMed article]
    transporter activity [IEALink to PubMed article]
    nucleotide binding [IEALink to PubMed article]
    D-methionine transmembrane transporter activity [IEALink to PubMed article]
    ATP binding [IEALink to PubMed article]
    inorganic phosphate transmembrane transporter activity [IEALink to PubMed article]
    nucleoside-triphosphatase activity [IEALink to PubMed article]
    polyamine-transporting ATPase activity [IEALink to PubMed article]
    phosphonate transmembrane-transporting ATPase activity [IEALink to PubMed article]
    toxin transporter activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVGNLIVLSS AGAAVYFRDS PGLSAGLVGL SVSYALNITQ TLNWAVRMTS ELETNIVAVE  60
   61 RINEYTITPT EGNNSQSLAP KSWPENGEIS IKNFSVRYRP GLDLVLHGVT AHISPCEKIG 120
  121 IVGRTGAGKS SLTLALFRII EADGGCIEID GTNIADLLLE QLRSRLTIVP QDPVLFSGTM 180
  181 RMNLDPFFAF SDDQIWEALR NAHLDSFVKS LQEGLHHHIS EGGENLSVGQ RQLICLARAL 240
  241 LRKTKVLVLD EAAAAVDVET DSLLQKTIRE QFKDCTVLTI AHRLNTVMDS DRLLVLDKGC 300
  301 VAEFDTPKKL LSNPDGIFYS MAKDANVV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..328] PSI-BLAST 95.69897 No description for 2hydA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • substrate-specific transmembrane transporter activity
    		•  3.4837867129694 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  3.35436118751376 bayes_pls_golite062009
  • transporter activity
    		•  3.10463051760206 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  3.08390071341252 bayes_pls_golite062009
  • drug transmembrane transporter activity
    		•  2.97119034312001 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.95886887664984 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.89122312915795 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.81593838944939 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.79724985811732 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.79347973548337 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  2.67957846350199 bayes_pls_golite062009
  • carboxylic acid transmembrane transporter activity
    		•  2.67815672695824 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  2.61775212528604 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  2.61467977505707 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  2.57552435627908 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  2.57107347424517 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  2.57054427875021 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  2.50494515048649 bayes_pls_golite062009
  • ATPase activity
    		•  2.44176688200537 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  2.43862163407966 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  2.40292717311506 bayes_pls_golite062009
  • amine transmembrane transporter activity
    		•  2.29486577878686 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  2.26365379756656 bayes_pls_golite062009
  • binding
    		•  2.21604035604783 bayes_pls_golite062009
    		• 2.20174656498665 bayes_pls_golite062009
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  2.1115517127743 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.91091452720653 bayes_pls_golite062009
  • transition metal ion transmembrane transporter activity
    		•  1.82177108193332 bayes_pls_golite062009
  • amino acid transmembrane transporter activity
    		•  1.59627719545436 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  1.58971273330352 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  1.4343912580786 bayes_pls_golite062009
  • hydrolase activity
    		•  1.40217504818333 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions
    		•  1.23799860254751 bayes_pls_golite062009
  • protein binding
    		•  1.22129154759482 bayes_pls_golite062009
  • cation channel activity
    		•  0.997064416395892 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.929901285538132 bayes_pls_golite062009
  • nucleotide binding
    		•  0.922442819194247 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.920987930180051 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.920926158369519 bayes_pls_golite062009
  • copper ion transmembrane transporter activity
    		•  0.798934081014025 bayes_pls_golite062009
  • di-, tri-valent inorganic cation transmembrane transporter activity
    		•  0.767424210804186 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  0.69784475011795 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  0.688632087597536 bayes_pls_golite062009
  • anion transmembrane-transporting ATPase activity
    		•  0.563503770238611 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  0.562664200036023 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  0.559798751382976 bayes_pls_golite062009
  • branched-chain aliphatic amino acid transmembrane transporter activity
    		•  0.442220326523999 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  0.43332053110728 bayes_pls_golite062009
  • ATP binding
    		•  0.41092997612902 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.385813421701492 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.377870145186619 bayes_pls_golite062009
  • potassium channel activity
    		•  0.329290830676079 bayes_pls_golite062009
  • gated channel activity
    		•  0.299411774392227 bayes_pls_golite062009
  • GTPase activity
    		•  0.20164416416912 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.194779852865789 bayes_pls_golite062009
  • iron ion transmembrane transporter activity
    		•  0.160869143323446 bayes_pls_golite062009
  • ion channel activity
    		•  0.154779598791225 bayes_pls_golite062009
  • amino acid-transporting ATPase activity
    		•  0.147644650870465 bayes_pls_golite062009
  • amine-transporting ATPase activity
    		•  0.135455889967401 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.134817721656507 bayes_pls_golite062009
  • channel activity
    		•  0.134817721656507 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  0.126911677161968 bayes_pls_golite062009
  • protein transporter activity
    		•  0.104820191623932 bayes_pls_golite062009
  • cation-transporting ATPase activity
    		•  0.0536898657672154 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle