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Protein Overview: CE33848

General Information:
Name(s) found: CE33848 [WormBase]
Description(s) found:
Found 15 descriptions.
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  • WBGene00013811 status:Partially_confirmed UniProt:Q9U2T8 protein_id:CAB55139.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 528 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: signal transduction [IEALink to PubMed article]
    protein amino acid phosphorylation [IEALink to PubMed article]
    Molecular Function: ATP binding [IEALink to PubMed article]
    protein tyrosine kinase activity [IEALink to PubMed article]
    non-membrane spanning protein tyrosine kinase activity [IEALink to PubMed article]
    protein kinase activity [IEALink to PubMed article]
    protein serine/threonine kinase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKPSKCQSP GDSSISAKEN DAQSNRSRDS KVAPKSEGLA TGLDETEWKS RLTTPEIVLK  60
   61 EIRTLEGVSY YHGMVARDLV ESKLTRCGDY LIRATDNRIM EFEFILSFFN KKRIHSHLTI 120
  121 KCDVEAGKWA LGLLSVNQFS SVVDLTNFYK TNPIGAGFFL KRAISKGKYM IAHDRIKYSP 180
  181 KDDLLGTGNF SDVFRGKIEL ENQMVNVALK TTKLLDDTMD PTKNVKANKI KKEMIQEAEV 240
  241 MSQLRHANVT SFFGIAVDRL PILLIIEFCN GGNLQGHLIK FGDRIGTNER FLYLHDASAG 300
  301 LNYIHAMSIT HRDIAARNCL ISVNGFVKLS DFGMGLKVRR NESAEKVAED DDGKENKEPK 360
  361 LPVRWMSPEL VDTPDAFSKM SDMWSLGILA YEIFTNATKP FFNLDDTDVM QTVKSGKHPP 420
  421 LPLSMGPDLI RLLKDVLVAA PTQRTTADKF YNELHVLCTQ KGALSLNGLT INQIRGISRK 480
  481 RVEHVTYRKL SYAIRMVTRE IGVMHHRRCW LMLFGGERSE VSSRTGSF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..473] PSI-BLAST 110.0 No description for 2h8hA was found.
    2 View Details [474..528] PSI-BLAST 5.39794 EphA4 receptor tyrosine kinases

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphotransferase activity, alcohol group as acceptor
    		•  5.49988294224815 bayes_pls_golite062009
  • protein kinase activity
    		•  5.4586557943719 bayes_pls_golite062009
  • kinase activity
    		•  5.3287080791198 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.96052051118534 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  4.46381887831481 bayes_pls_golite062009
  • transferase activity
    		•  3.97138602499442 bayes_pls_golite062009
  • phosphoinositide 3-kinase binding
    		•  3.43994026029707 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase activity
    		•  3.41480681854114 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  3.40140621607334 bayes_pls_golite062009
  • CD8 receptor binding
    		•  3.34636716492159 bayes_pls_golite062009
  • epidermal growth factor receptor binding
    		•  2.9751846707539 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  2.8153155526437 bayes_pls_golite062009
  • binding
    		•  2.74863538127007 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  2.59526003830791 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.52531786618214 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.46424348876434 bayes_pls_golite062009
  • molecular transducer activity
    		•  2.40586892801446 bayes_pls_golite062009
  • signal transducer activity
    		•  2.40586892801446 bayes_pls_golite062009
  • receptor activity
    		•  2.39311927684508 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.37122853419919 bayes_pls_golite062009
  • protein binding
    		•  2.276111749106 bayes_pls_golite062009
  • tubulin binding
    		•  2.18641675163967 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.12615078788254 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  2.10379226653669 bayes_pls_golite062009
  • SH2 domain binding
    		•  2.08937039830657 bayes_pls_golite062009
  • ATP binding
    		•  1.97600611746091 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.93596671856664 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.90928021591891 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  1.9016235206634 bayes_pls_golite062009
  • microtubule binding
    		•  1.88110801192607 bayes_pls_golite062009
  • actin binding
    		•  1.87817875565699 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
    		•  1.81249386965144 bayes_pls_golite062009
  • molecular adaptor activity
    		•  1.81145713371725 bayes_pls_golite062009
  • non-membrane spanning protein tyrosine kinase activity
    		•  1.66669268613198 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.65732943334212 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.65726906484847 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.63763394711025 bayes_pls_golite062009
  • vinculin binding
    		•  1.63216315345235 bayes_pls_golite062009
  • nucleotide binding
    		•  1.63195828048121 bayes_pls_golite062009
  • SH3/SH2 adaptor activity
    		•  1.59474164216385 bayes_pls_golite062009
  • PTB domain binding
    		•  1.56656184134104 bayes_pls_golite062009
  • growth factor binding
    		•  1.53863828216563 bayes_pls_golite062009
  • MAP kinase kinase activity
    		•  1.42275431028856 bayes_pls_golite062009
  • gamma-tubulin binding
    		•  1.28511591054866 bayes_pls_golite062009
  • kinase binding
    		•  1.26086833316556 bayes_pls_golite062009
  • catalytic activity
    		•  1.21655087018101 bayes_pls_golite062009
  • transporter activity
    		•  1.11833481501707 bayes_pls_golite062009
  • transforming growth factor beta receptor activity
    		•  1.10045286406485 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase activity
    		•  1.10045286406485 bayes_pls_golite062009
  • protein kinase binding
    		•  1.06030596516506 bayes_pls_golite062009
  • cation channel activity
    		•  1.04999722123563 bayes_pls_golite062009
  • insulin receptor substrate binding
    		•  0.98689034826741 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.97575992765505 bayes_pls_golite062009
  • protein binding, bridging
    		•  0.83823250804321 bayes_pls_golite062009
  • MAP kinase activity
    		•  0.81943579965027 bayes_pls_golite062009
  • actin filament binding
    		•  0.794152600084 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.794058505655489 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.775404673285876 bayes_pls_golite062009
  • fibroblast growth factor receptor activity
    		•  0.75189004129952 bayes_pls_golite062009
  • DNA binding
    		•  0.714163549867672 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.705905455086486 bayes_pls_golite062009
  • insulin binding
    		•  0.665093877251839 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.612883428421652 bayes_pls_golite062009
  • transcription factor activity
    		•  0.563262875317016 bayes_pls_golite062009
  • JUN kinase kinase kinase kinase activity
    		•  0.546647574638943 bayes_pls_golite062009
  • activin binding
    		•  0.510364757301021 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
    		•  0.499492353295369 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.487555922788887 bayes_pls_golite062009
  • protein serine/threonine/tyrosine kinase activity
    		•  0.48345772948903 bayes_pls_golite062009
  • transcription activator activity
    		•  0.481994471237116 bayes_pls_golite062009
  • enzyme binding
    		•  0.46284745266176 bayes_pls_golite062009
  • magnesium ion binding
    		•  0.393328812780268 bayes_pls_golite062009
  • 3-phosphoinositide-dependent protein kinase binding
    		•  0.372842462336059 bayes_pls_golite062009
  • MAP kinase kinase kinase activity
    		•  0.37115026509016 bayes_pls_golite062009
  • phosphotyrosine binding
    		•  0.311079584914389 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.287189255116606 bayes_pls_golite062009
  • channel activity
    		•  0.287189255116606 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  0.261869836686301 bayes_pls_golite062009
  • ion channel activity
    		•  0.241519346930618 bayes_pls_golite062009
  • protein complex binding
    		•  0.239339759110451 bayes_pls_golite062009
  • insulin receptor activity
    		•  0.188254408239569 bayes_pls_golite062009
  • cell adhesion molecule binding
    		•  0.150740450460731 bayes_pls_golite062009
  • JUN kinase kinase kinase activity
    		•  0.0613131034808199 bayes_pls_golite062009
  • transforming growth factor beta receptor activity, type I
    		•  0.0506751594607393 bayes_pls_golite062009
  • metal ion binding
    		•  0.046173055856133 bayes_pls_golite062009
  • cation binding
    		•  0.046173055856133 bayes_pls_golite062009
  • ion binding
    		•  0.0389662058697694 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
    		•  3.32682088990761 bayes_pls_golite062009
  • protein binding
    		•  3.17959185034169 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.51450869851362 bayes_pls_golite062009
  • DNA binding
    		•  2.06580952974787 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.00979605019137 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.71028970433077 bayes_pls_golite062009
  • transcription factor activity
    		•  1.68824580477027 bayes_pls_golite062009
  • transferase activity
    		•  1.32851434738219 bayes_pls_golite062009
  • sphingomyelin synthase activity
    		•  1.30282127595043 bayes_pls_golite062009
  • ceramide cholinephosphotransferase activity
    		•  1.30282127595043 bayes_pls_golite062009
  • signal transducer activity
    		•  1.1654493104048 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.1654493104048 bayes_pls_golite062009
  • chromatin binding
    		•  0.588390918115119 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.378140581508185 bayes_pls_golite062009
  • catalytic activity
    		•  0.0451617952658021 bayes_pls_golite062009
  • kinase binding
    		•  0.00390249209859306 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle