General Information: |
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Name(s) found: |
TNFA_RAT
[Swiss-Prot]
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Description(s) found:
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Organism: | Rattus norvegicus |
Length: | 235 amino acids |
Gene Ontology: |
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Cellular Component: |
integral to plasma membrane
[UNKNOWN][IEA]
extracellular space [UNKNOWN][IDA][TAS] membrane raft [UNKNOWN][IEA] integral to membrane [IDA] extracellular region [IEA] plasma membrane [UNKNOWN][IEA] cell surface [UNKNOWN] |
Biological Process: |
JNK cascade
[UNKNOWN]
positive regulation of mitosis [IMP] glucose metabolic process [UNKNOWN][IEA] induction of apoptosis via death domain receptors [UNKNOWN][IEA] positive regulation of transcription factor activity [UNKNOWN] induction of apoptosis by extracellular signals [UNKNOWN] positive regulation of NF-kappaB transcription factor activity [UNKNOWN][IEA] negative regulation of L-glutamate transport [IDA] activation of MAPK activity [UNKNOWN][IEA] regulation of insulin secretion [UNKNOWN][IEA] inflammatory response [UNKNOWN][TAS] positive regulation of chronic inflammatory response to antigenic stimulus [UNKNOWN] positive regulation of gene-specific transcription [UNKNOWN][IEA] anti-apoptosis [UNKNOWN][IEA] positive regulation of membrane protein ectodomain proteolysis [UNKNOWN][IEA] induction of apoptosis [UNKNOWN][IDA] chronic inflammatory response to antigenic stimulus [UNKNOWN][IEA] protein import into nucleus, translocation [UNKNOWN][IEA] apoptosis [IDA] humoral immune response [UNKNOWN][IEA] positive regulation of interferon-gamma production [UNKNOWN] positive regulation of cytokine secretion [UNKNOWN][IEA] activation of caspase activity [UNKNOWN][IEA] calcium-mediated signaling [IDA] positive regulation of chemokine production [UNKNOWN][IEA] receptor biosynthetic process [UNKNOWN][IEA] defense response to Gram-positive bacterium [UNKNOWN] negative regulation of lipid catabolic process [UNKNOWN][IEA] negative regulation of branching involved in lung morphogenesis [UNKNOWN] positive regulation of inflammatory response [IMP] positive regulation of synaptic transmission [IMP] positive regulation of calcidiol 1-monooxygenase activity [UNKNOWN][IEA] positive regulation of NF-kappaB import into nucleus [UNKNOWN][IEA] defense response to bacterium [UNKNOWN][IEA] induction of necroptosis by extracellular signals [UNKNOWN][IEA] organ morphogenesis [UNKNOWN][IEA] positive regulation of vitamin D biosynthetic process [UNKNOWN][IEA] negative regulation of interleukin-6 production [UNKNOWN][IEA] tumor necrosis factor-mediated signaling pathway [UNKNOWN][IEA] transformed cell apoptosis [UNKNOWN][IEA] negative regulation of growth of symbiont in host [UNKNOWN] negative regulation of transcription [UNKNOWN][IEA] positive regulation of humoral immune response mediated by circulating immunoglobulin [UNKNOWN] sequestering of triglyceride [UNKNOWN][IEA] positive regulation of interleukin-6 production [UNKNOWN][IEA] positive regulation of nitric oxide biosynthetic process [UNKNOWN][IEA] multicellular organismal development [UNKNOWN][IEA] negative regulation of cell proliferation [IDA] positive regulation of I-kappaB kinase/NF-kappaB cascade [UNKNOWN][IGI] regulation of I-kappaB kinase/NF-kappaB cascade [UNKNOWN] positive regulation of transcription [UNKNOWN][IEA] response to virus [UNKNOWN][IEA] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][IEA] epithelial cell proliferation involved in salivary gland morphogenesis [UNKNOWN][IEA] positive regulation of neuron apoptosis [IMP] negative regulation of cytokine secretion during immune response [UNKNOWN][IEA] response to mechanical stimulus [IEP] negative regulation of transcription from RNA polymerase II promoter [UNKNOWN][IEA] positive regulation of smooth muscle cell proliferation [UNKNOWN][IEA] positive regulation of protein transport [IDA] necrotic cell death [UNKNOWN] regulation of immunoglobulin secretion [UNKNOWN][IEA] regulation of osteoclast differentiation [UNKNOWN][IEA] response to glucocorticoid stimulus [UNKNOWN][IEA] positive regulation of interleukin-18 production [IMP] negative regulation of viral genome replication [UNKNOWN][IEA] regulation of branching involved in salivary gland morphogenesis [UNKNOWN][IEA] negative regulation of gene-specific transcription [UNKNOWN] signal transduction [IDA] negative regulation of glucose import [UNKNOWN][IDA] positive regulation of translational initiation by iron [UNKNOWN][IEA] defense response [UNKNOWN] regulation of cell proliferation [UNKNOWN] osteoclast differentiation [UNKNOWN] cell activation [IDA] regulation of protein amino acid phosphorylation [UNKNOWN] cellular extravasation [UNKNOWN] response to drug [IEP] negative regulation of apoptosis [UNKNOWN] positive regulation of JNK cascade [UNKNOWN][IEA] positive regulation of protein amino acid phosphorylation [UNKNOWN][IEA] positive regulation of apoptosis [IMP] extracellular matrix organization [UNKNOWN][IEA] positive regulation of heterotypic cell-cell adhesion [UNKNOWN][IEA] leukocyte migration [UNKNOWN] leukocyte tethering or rolling [UNKNOWN][IEA] positive regulation of cytokine production [UNKNOWN] positive regulation of chemokine biosynthetic process [UNKNOWN][IEA] |
Molecular Function: |
identical protein binding
[UNKNOWN][IEA]
protein binding [UNKNOWN] tumor necrosis factor receptor binding [UNKNOWN][IDA][TAS] promoter binding [UNKNOWN] transcription activator activity [UNKNOWN] cytokine activity [UNKNOWN][TAS] transcription repressor activity [UNKNOWN] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MSTESMIRDV ELAEEALPKK MGGLQNSRRC LCLSLFSFLL VAGATTLFCL LNFGVIGPNK 60 61 EEKFPNGLPL ISSMAQTLTL RSSSQNSSDK PVAHVVANHQ AEEQLEWLSQ RANALLANGM 120 121 DLKDNQLVVP ADGLYLIYSQ VLFKGQGCPD YVLLTHTVSR FAISYQEKVS LLSAIKSPCP 180 181 KDTPEGAELK PWYEPMYLGG VFQLEKGDLL SAEVNLPKYL DITESGQVYF GVIAL |
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