YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: AEP3

General Information:
Name(s) found: AEP3 / YPL005W [SGD]
Description(s) found:
Found 28 descriptions.
SHOW ALL
  • Peripheral mitochondrial inner membrane protein, located on the matrix face of the membrane; stabilizes the bicistronic AAP1-ATP6 mRNA encoding subunits 6 and 8 of the ATP synthase complex [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 606 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    extrinsic to membrane [IDALink to PubMed article]
    mitochondrial inner membrane [IDALink to PubMed article]
    Biological Process: mRNA metabolic process [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTLRCLTQA LSKSGREAPK LYQKVIFPGL FREGIPIANV KKVDEKIIDS PTSTSVNGEA  60
   61 KKIVRHGVKY EREQVKEYLS SLPTLTLSRK QIRDDYDEER AKRMYMFSKQ TNSSNKFQKL 120
  121 LTAKSQEFTR ELLTLLIDCT SNEKNSGPER FTRKFLKFSN DEIPPLPDFS KNPQLFENYI 180
  181 GILSHTKFNF RSSSKLNGIV RKMLRHLLHP TNKTTLPLRS AQVYNDSIYF FSEHFDFASC 240
  241 REIFAQMKAE GTKPNTITFN LLLRNVVKNS HIRKTKHPDD EVLFYLRSMR NHGVFADVIT 300
  301 WTTCYNFLRD EVSRQLYIVQ MGEHLGNFNV NFVYTVLRNG DYRAEDCLKV LAANSLPISR 360
  361 KTFYLCIERL LNEEQLETAS KLLDYGFQHL KSNFKLDSEA MNHFMRVFAN KGRSDLAFLC 420
  421 YNTCRKIYKI KPDSQTFEML FKALVRNGNT KNFGAVLQYI KDLKVSEGFG LRTSYWRTKA 480
  481 DSIFKFGSPN TLSEKSIEKA RKLLGNLIAS EGEFSWKIWK ESDSSQKKIL RFLGCIPTTL 540
  541 RCTNTAQDHQ KPTNLPSNIS QKKREYRNRV KAIATKAALE KRMAYIKDND VAFKKELVKR 600
  601 RIVGEV

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) AEP3 CDC20 FAB1 FOL2 GZF3 LSP1 NOP13 PIL1 PKH1 PRP16 PSK2 RGC1 RPL9B YLR179C YMR086W YTA6

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data AEP3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..138] MSA 2.700995 View MSA. No confident structure predictions are available.
    2 View Details [139..345] MSA 8.802996 View MSA. No confident structure predictions are available.
    3 View Details [346..463] PSI-BLAST 3.522879 Designed protein cTPR3
    4 View Details [464..606] MSA 2.748986 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  1.69757163267229 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.967526235944614 bayes_pls_golite062009
  • protein binding
    		•  0.931467806305272 bayes_pls_golite062009
  • RNA binding
    		•  0.675746721046834 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.663212626739423 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.54028771192401 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  0.465749123849318 bayes_pls_golite062009
  • hydrolase activity
    		•  0.443144569020145 bayes_pls_golite062009
  • DNA binding
    		•  0.36234393273743 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle