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Protein Overview: FDH1

General Information:
Name(s) found: FDH1 / YOR388C [SGD]
Description(s) found:
Found 30 descriptions.
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  • NAD(+)-dependent formate dehydrogenase, may protect cells from exogenous formate [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 376 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDALink to PubMed article]
    Biological Process: NADH regeneration [TASLink to PubMed article]
    formate catabolic process [IGILink to PubMed article][TASLink to PubMed article]
    Molecular Function: formate dehydrogenase activity [IGILink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKGKVLLVL YEGGKHAEEQ EKLLGCIENE LGIRNFIEEQ GYELVTTIDK DPEPTSTVDR  60
   61 ELKDAEIVIT TPFFPAYISR NRIAEAPNLK LCVTAGVGSD HVDLEAANER KITVTEVTGS 120
  121 NVVSVAEHVM ATILVLIRNY NGGHQQAING EWDIAGVAKN EYDLEDKIIS TVGAGRIGYR 180
  181 VLERLVAFNP KKLLYYDYQE LPAEAINRLN EASKLFNGRG DIVQRVEKLE DMVAQSDVVT 240
  241 INCPLHKDSR GLFNKKLISH MKDGAYLVNT ARGAICVAED VAEAVKSGKL AGYGGDVWDK 300
  301 QPAPKDHPWR TMDNKDHVGN AMTVHISGTS LDAQKRYAQG VKNILNSYFS KKFDYRPQDI 360
  361 IVQNGSYATR AYGQKK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Gavin AC, et al. (2002) ACC1 CCT8 CLU1 CPA2 FDH1 GCN20 GFA1 GUS1 ILV1 KAP123 LYS12 MRPL3 PSA1 RPA135 RPB2 RPN10 RPN11 RPN12 RPN8 RPT3 RPT5 RPT6 SAM1 SEC27 SMC3 TCB1 TIF1, TIF2 TSA1 TUB3 URA7 VAS1 YOL098C

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen ATG12 FDH1 1 Unpublished Fields Lab Data
    View Screen CTR86 FDH1 1 Unpublished Fields Lab Data
    View Screen UBC7 FDH1 1 Unpublished Fields Lab Data
    View Screen RRB1 FDH1 1 Unpublished Fields Lab Data
    View Screen KAP104 FDH1 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..123]
    [327..376]    		 PSI-BLAST 953.218487 Formate dehydrogenase
    2 View Details [124..326] PSI-BLAST 953.218487 Formate dehydrogenase


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle