YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: LDB19

General Information:
Name(s) found: LDB19 / YOR322C [SGD]
Description(s) found:
Found 30 descriptions.
SHOW ALL
  • Protein involved in regulating the endocytosis of plasma membrane proteins by recruiting the ubiquitin ligase Rsp5p to its target; localization changes in response to nutrient levels; null mutant has reduced affinity for alcian blue dye [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 818 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    clathrin-coated vesicle [IDALink to PubMed article]
    Biological Process: telomere maintenance [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFSRLTSTH QSNHNGYSNS NKKGQSLPLT LSIDVESPPC VLYGSAMESS GAVLSGLFTV  60
   61 TVVDPYSSAE DKSLKNTESN VSTTSKSLKR KSTFGSALSS RLSSLSASTS NISPSTSSTS 120
  121 ISHSPTPANL RIMAGYTKIT ITSVTLSLVQ KIHFHKPFVP NISSMQTCMN CKTKITNMKS 180
  181 WEIQSNTQDL SVGSHSYPFS YLIPGSVPCS SSLGATAETQ VKYELIAVVT YIDPHRNSFS 240
  241 SGHSTPRKEG SSSKKRLLQL AMPIAVTRSI PRGPDKNSLR VFPPTELTAA AVLPNVVYPK 300
  301 STFPLEMKLD GVSSGDRRWR MRKLSWRIEE TTRVKAHACP VHKHELRQLE EQVKIKESEK 360
  361 SKKPRSHIKR YGELGPQIRV AVNSLENMPS QRLPGEPGRE QAPNSSGPAS TGNVGLDDEN 420
  421 PVNEDEEDQP GSEFIHPSDD ALRQELLMQQ QRARQQQLQQ ELKNNSSLFT EEVRIISKGE 480
  481 MKSGWKTDFD NNGKIELVTE IDCMGLNSGV SNPVMHASTL QTPSTGNKKP SINVACDIQD 540
  541 PNLGLYVSHI LAVEIVVAEE TLQYANGQPI RKPNSKNKKE TNNNTMNVHN PDQRLAELSP 600
  601 IFANRNTPKV RRMGPEDITP VNSNKSNHST NKEKASNGAS NSNIVSVPTG AARVLRMQFR 660
  661 LTVTERSGLG ISWDEEVPPI YQDVELLSPP CYELSINNGI KNKLYSTMST PVRSEDDFVG 720
  721 GSDEDIGNYE SQGLEPGPNV QEVTITQNKL TIPPTAHHYQ PASSSQRSLT TVQSPPLESV 780
  781 VSVQGSVPFR GHVLTPHSTR DIRIQNFSDF LDSNRITQ

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ADE6 BUL1 LDB19 RSP5 RUP1 UBP2 YHR131C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data LDB19 and CHC1 Huh WK, et al. (2003)
    View Data LDB19 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..79] deduced N/A No confident structure predictions are available.
    2 View Details [80..387] MSA 3.004923 View MSA. No confident structure predictions are available.
    3 View Details [388..818] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • clathrin binding
    		•  2.57748868504781 bayes_pls_golite062009
  • binding
    		•  2.01341910518392 bayes_pls_golite062009
  • protein binding
    		•  1.608080422834 bayes_pls_golite062009
  • transporter activity
    		•  1.10239137184953 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.949536954960448 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.781060752903079 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.660409340901077 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.56446678342098 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.486294295028555 bayes_pls_golite062009
  • channel activity
    		•  0.465630241372545 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.465630241372545 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  0.455589501590218 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  0.44519612509266 bayes_pls_golite062009
  • potassium channel activity
    		•  0.423464159542763 bayes_pls_golite062009
  • cation channel activity
    		•  0.406614358442595 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  0.402494949667906 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  0.39571309893169 bayes_pls_golite062009
  • ion channel activity
    		•  0.395022246697853 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  0.387394052239826 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  0.326855275194847 bayes_pls_golite062009
  • gated channel activity
    		•  0.266124158878986 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.0852462445742306 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle