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Protein Overview: SLG1

General Information:
Name(s) found: SLG1 / YOR008C [SGD]
Description(s) found:
Found 28 descriptions.
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  • Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway involved in maintenance of cell wall integrity; involved in organization of the actin cytoskeleton; secretory pathway Wsc1p is required for the arrest of secretion response [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 378 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [IDALink to PubMed article]
    plasma membrane [IDALink to PubMed article]
    actin cap [IDALink to PubMed article]
    Biological Process: response to heat [IMPLink to PubMed articleLink to PubMed article]
    response to osmotic stress [IGILink to PubMed article][IMPLink to PubMed article]
    cellular cell wall organization [IMPLink to PubMed article]
    Rho protein signal transduction [IGILink to PubMed article][IMPLink to PubMed articleLink to PubMed article]
    endocytosis [IMPLink to PubMed article]
    actin cytoskeleton organization [IMPLink to PubMed article]
    Molecular Function: transmembrane receptor activity [IGILink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRPNKTSLLL ALLSILSQAN AYEYVNCFSS LPSDFSKADS YNWQSSSHCN SECSAKGASY  60
   61 FALYNHSECY CGDTNPSGSE STSSSCNTYC FGYSSEMCGG EDAYSVYQLD SDTNSNSISS 120
  121 SDSSTESTSA SSSTTSSTTS STTSTTSSTT SSTTSSMASS STVQNSPEST QAAASISTSQ 180
  181 SSSTVTSESS LTSDTLATSS TSSQSQDATS IIYSTTFHTE GGSTIFVTNT ITASAQNSGS 240
  241 ATGTAGSDST SGSKTHKKKA NVGAIVGGVV GGVVGAVAIA LCILLIVRHI NMKREQDRME 300
  301 KEYQEAIKPV EYPDKLYASS FSSNHGPSSG SFEEEHTKGQ TDINPFDDSR RISNGTFING 360
  361 GPGGKNNVLT VVNPDEAD

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) BUD6 CLA4 GIC1 MID2 MSB2 PEA2 PFY1 SHO1 SLG1 WSC2 WSC3 WSC4

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run RLF2 phosphorylation data - cascade search Green EM, et al (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen PRP40 SLG1 2 Unpublished Fields Lab Data
    View Screen YJU2 SLG1 1 Unpublished Fields Lab Data
    View Screen SUI1 SLG1 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data SLG1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..64] ORFEUS 11.43 Fibrinogen
    2 View Details [65..378] ORFEUS 12.95 Sec24


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle