YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: WSC4

General Information:
Name(s) found: WSC4 / YHL028W [SGD]
Description(s) found:
Found 23 descriptions.
SHOW ALL
  • ER membrane protein involved in the translocation of soluble secretory proteins and insertion of membrane proteins into the ER membrane; may also have a role in the stress response but has only partial functional overlap with WSC1-3 [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 605 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [ISSLink to PubMed article]
    endoplasmic reticulum membrane [IDALink to PubMed article]
    Biological Process: SRP-dependent cotranslational protein targeting to membrane, translocation [ISSLink to PubMed article]
    response to heat [IGILink to PubMed article][ISSLink to PubMed articleLink to PubMed article]
    protein targeting to ER [IMPLink to PubMed article]
    response to stress [IGILink to PubMed article]
    Molecular Function: transmembrane receptor activity [IGILink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQTSMVSAKV SIWLVCSVIC SSLVRATQSV CSSQNTATTD GVRNQFQSNG WCSNNCAGHQ  60
   61 FAIVQGFMCW CSDSEPSTQT SVGDCSGTCP GYGYEDCGNA DKDLFGYIYL GQTPLSSVQS 120
  121 VETSTESSVY VSSSSITSSS STSIVDTTTI SPTLTSTSTT PLTTASTSTT PSTDITSALP 180
  181 TTTSTKLSTS IPTSTTSSTS TTTSTSSSTS TTVSVTSSTS TTTSTTSSTL ISTSTSSSSS 240
  241 STPTTTSSAP ISTSTTSSTS TSTSTTSPTS SSAPTSSSNT TPTSTTFTTT SPSTAPSSTT 300
  301 VTYTSTTASP ITSTITSVNL QTSLKYSVIT VTSVHTMDTN ISEITSRYLT MKKVITQIYS 360
  361 STLGATPTSA VATTSASVGG RITNNNNSNT TNSNTPTNKS TEKKGYWDSP GKIAATFVVV 420
  421 GVVCLVIICI LIYLIHHYRT RPARKAQDFE NEYQSKFYQS KYPNEVTTTT LHTPSPSSNS 480
  481 TFSTPRLIYT DEKGQIMSES PSPRQSTYSL TAGSPPNDPS TLASPFHDPI LPRRTSTFLH 540
  541 SPIQKQHEKM ESNVTLGEDT VLVDQRLDPS KMLNTLANDD ATNHSTISLS DNVDYSRRVL 600
  601 RLMNE

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) SLG1 WSC2 WSC4

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RLF2 phosphorylation data - cascade search Green EM, et al (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data WSC4 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..114] Pfam 25.031517 WSC domain No confident structure predictions are available.
    2 View Details [115..281] MSA 3.203994 View MSA. No confident structure predictions are available.
    3 View Details [282..605] ORFEUS 12.29 Fibrinogen
    4 View Details [413..605] FFAS03 1.15 No description for 2j63A was found.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle