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Protein Overview: WSC2

General Information:
Name(s) found: WSC2 / YNL283C [SGD]
Description(s) found:
Found 23 descriptions.
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  • Partially redundant sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway involved in maintenance of cell wall integrity and recovery from heat shock; secretory pathway Wsc2p is required for the arrest of secretion response [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 503 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [ISSLink to PubMed article]
    cellular bud [IDALink to PubMed article]
    site of polarized growth [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: response to heat [IGILink to PubMed article][ISSLink to PubMed article]
    cellular cell wall organization [IGILink to PubMed article][IMPLink to PubMed article]
    Rho protein signal transduction [IGILink to PubMed article][ISSLink to PubMed article]
    actin cytoskeleton organization [TASLink to PubMed article]
    Molecular Function: transmembrane receptor activity [IGILink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHLDLIHKSF ILVWLIYIRA ALADQFTYKA CYSASDIRKL GLTYKGVYEY QSVSYCQNEC  60
   61 PGQAVVALFN GTGCYCGGSV AQLQSLTQVD SSKCDVSCAG WPYQNCGGSS AMNVYINNAA 120
  121 STADSTSSTA TSTSTTSSSS TSVSSKTSTK LDTKTSTSSS ATHSSSSSST TSTTTSSSET 180
  181 TTSSSSSSSS SSTSTTSTTS TTSSTTSTSS SPSTTSSSTS ASSSSETSST QATSSSTTST 240
  241 SSSTSTATVT STPSSTSIGT STHYTTRVVT QSVVSQANQQ ASTIFTTRTS VYATVSSTSS 300
  301 STSSLLNGKS SSSKSKGLSG GAIAGVVVGV VCGTVALLAL ALFFFVWKKR RQSSQHVDLE 360
  361 ETKQYQPYSL GDADANPVIP PSASSTNWHI PSRNNTALSK NTASTFATYD LPTRAPGGRD 420
  421 SIITGDAHNI SKRSHFPSVV YEEPPSIYNG NQRFSATSLP DMMEERQLHI VNPDNVSSNI 480
  481 GSNVSDGDDD YDDAKDSNNS SLR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) CDC42 MSB2 SHO1 SLG1 WSC2 WSC3 WSC4

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RLF2 phosphorylation data - cascade search Green EM, et al (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data WSC2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..108] Pfam 38.119186 WSC domain No confident structure predictions are available.
    2 View Details [109..188] deduced N/A No confident structure predictions are available.
    3 View Details [189..503] ab initio 12.62 No description for 1ei3A was found.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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