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Protein Overview: SKG3

General Information:
Name(s) found: SKG3 / YLR187W [SGD]
Description(s) found:
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  • gi|74644958|sp|Q06315.1|SKG3_YEAST RecName: Full=Protein SKG3; AltName: Full=Suppressor of lethality of KEX2-GAS1 double null mutant protein 3 [NCBI NR]
  • gi|6323216|ref|NP_013288.1| Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; potential Cdc28p substrate; similar to Caf120p and Skg4p; Skg3p [Saccharomyces cerevisia [NCBI NR]
  • gi|577196|gb|AAB67456.1| Ylr187wp [Saccharomyces cerevisiae] [NCBI NR]
  • pir||S51432 hypothetical protein YLR187w - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • Protein SKG3 OS=Saccharomyces cerevisiae GN=SKG3 PE=1 SV=1 [Swiss-Prot]
  • SKG3 Protein of unknown function, protein localizes to the cell periphery, cytoplasm, bud, and bud neck [mips]
  • Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; potential Cdc28p substrate; similar to Caf120p and Skg4p [SGD]
  • YLR187W, Chr XII from 524867-527947 [yeast_orfs2]
  • Chr XII from 524867-527947 [yeastorf3.fasta]
  • >Q06315 (Q06315) Chromosome XII COSMID 9470 [4932.FASTACCERV.txt]
  • SKG3 SGDID:S0004177, Chr XII from 524867-527947, Uncharacterized ORF [yeastflysequest.fasta]
  • Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; potential Cdc28p substrate [Saccharomyces cerevisiae]gi|1077412|pir||S51432 hypothetical protein YLR187w - yeast (S [nrdb_11152004_Chlamydomonas]
  • (Q06315) Ylr187wp [cerv4932.FASTAC]
  • SKG3 SGDID:S000004177, Chr XII from 524867-527947, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; potential Cdc28p substrate; similar to Caf1 [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • Ylr187wp [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; potential Cdc28p substrate; similar to Caf120p and Skg4p; Skg3p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • SKG3 SGDID:S000004177, Chr XII from 524867-527947, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; potential Cdc28p substrate; similar to Caf120p and Skg4p" [yeast-bovrabprots.fasta]
  • [chemostatdb.fasta]
  • Protein SKG3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SKG3 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • SKG3 SGDID:S000004177, Chr XII from 524865-527945, Genome Release 64-1-1, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; potential Cdc28p substrate; similar to Caf120p and Skg4p" [yeast-030211-contam.fasta]
  • SKG3 SGDID:S000004177, Chr XII from 524865-527945, Genome Release 64-2-1, Verified ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; potential Cdc28p substrate; similar to Skg4p; relocalizes from bud neck to cytoplasm upon DNA replication stress; SKG3 has a paralog, CAF120, that arose from the whole genome duplication" [20141208_orf_trans.fasta]
  • YLR187W SGDID:S000004177, Chr XII from 524865-527945, Genome Release 64-1-1, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; potential Cdc28p substrate; similar to Caf120p and Skg4p" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 1026 amino acids

    Gene Ontology:
    Cellular Component: cellular bud [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    cellular bud neck [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRIFSGVKS PKLSAPPKVF KNDESPSTPS SPKFDQGLRS LSASASRLFS NSISTPGSPT  60
   61 LDLPQEHSIN GDISPELVPI VTLLSAQAHR RYHYGIFLIL HDLKTDGTPA ARQWEECYGV 120
  121 LLGTQLALWD AKELSDSKNN KNTSTMKKAA SRPSFINFTD ASVRSLDAND QVIIASENEK 180
  181 TKKDLDNVLV VSTTLKNRYF LKFKNSKSFK TWNAAIRLSL FEFTALQEAY TGSFLSSRGV 240
  241 KLGDIKVVMA DTKFTYEDWV SVRFGTGMPW KRCYAVISPQ SGKKKKNSKG SICFYENNKK 300
  301 TKKSNIMTTV VDARALYAVY PSSPILIDTS TIIKLEGFVS FDKSEEPQET NLFIMPEKHQ 360
  361 GVPGYDTIIR FLIPAMNAFY LYGRPKGLIA NRTDPDSLLF ALPTLPHIYY LQVDDVLSLT 420
  421 KDKNYIHWSA ADWRNNIVQV LQKKLSKGYK GCGNKTVSVS SGMMKSPAIS SAELFEGYDS 480
  481 LPERQMESPQ KSKMKSPTLA STDDINSASA SVNSHATSVK QTELFVTDNS SKINDSVSAQ 540
  541 SSVTTNFKDT FTTPMTSGML NHENSERSFG SGLKLKITDS NLENMEDVEA KSANEFSTTP 600
  601 EDKHIHLANA AELSALYDKY STSPFGKSEA NSSPKPQKLE VKDRSKNENR SPYERYVGTS 660
  661 AESKTFEIGN VRESKSTINT SLSSPLRVED SRRSKNEDLG SLKEFEELSQ KISNMGMANI 720
  721 SSEALSDTAE NSSFVTDLNL NINNSSSVNL NEEQRVPDFG EENVFDPDYM EQNQMLETES 780
  781 RYTTDEFDFS DNQDAASSNY SNGQTNRTVT ETLSASDRND KIPHSSLFTN LNQLTSNGGN 840
  841 YQDREDFSGD QINKPQQSQP LHVKGPQTSS FGYRNSSANS SQPQAPYPVG RPLGKIRTGP 900
  901 LTVQPMQQGG NSSMYSFQSS QHRFHSSQQR QNQSLSFRNN TYGSGNNQNT FHPSPQLQQQ 960
  961 PQNMRYLNNK LPINDRSPIP QTQHHVPDGR PSLHINTTNR TNPLTAQSGF SQFMPPNSTS1020
 1021 TNPYSS

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ATE1 CDC28 CKS1 CLB2 CLB3 CLB4 CLB5 SIC1 SKG3
    View Details Ho Y, et al. (2002) AHA1 ARP2 BCK1 CPR6 EGD2 FOL2 GAL7 GND1 IDH1 ILV5 IPP1 KIC1 KIN2 LHS1 LYS12 MKK2 MKT1 OYE2 PDC6 PIL1 PMA1 QCR2 RCN2 RPN6 RPT3 SIS1 SKG3 SLT2 SMK1 TIF1, TIF2

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #02 Alpha Factor Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data SKG3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..72] deduced N/A No confident structure predictions are available.
    2 View Details [73..278] Pfam 8.356547 PH domain No confident structure predictions are available.
    3 View Details [279..350] deduced N/A No confident structure predictions are available.
    4 View Details [351..451] MSA 1.006981 View MSA. Confident ab initio structure predictions are available.
    5 View Details [452..1026] MSA 48.361998 View MSA. No confident structure predictions are available.
    6 View Details [741..856] deduced N/A No confident structure predictions are available.
    7 View Details [857..1026] MSA 6.308997 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.37468867147476 bayes_pls_golite062009
  • protein binding
    		•  1.98056222560389 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle